19 research outputs found
THERMAL REARRANGEMENT OF A PHOSPHORUS YLIDE: METHANOLYSIS AND HYDROLYSIS OF THE OBTAINED PHOSPHORANES
No full textTriple Helix Formation and Homologous Strand Exchange in Pyrene-Labeled Oligonucleotides
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YLURES SANS SEL, ÉVOLUTION EN PHOSPHORANES ET ÉQUILIBRE YLURE ⇄ PHOSPHORANE; INFLUENCE DES RÉACTIFS DE PIÉGEAGE: III PIÉGEAGE PROTIQUE
No full textInferring biologically relevant molecular tissue substructures by agglomerative clustering of digitized spatial transcriptomes with multilayer
No full textInternational audienceSodium phenylacetate (NaPa) and some bisphosphonates demonstrated antiproliferative and proapoptotic properties against cancer. We have previously shown that NaPa inhibited cell proliferation of MCF7-ras tumor breast cells both in vitro and in vivo. On the other hand, bisphosphonate activities have only been demonstrated in vitro. Here we evaluated the antitumor effects of a new bisphosphonate, the phenylacetate-bisphosphonate (PaBp), on human breast cancer MCF7 and MCF7-ras cell lines, both in vitro and in vivo. To our knowledge, this is the first report indicating the use of a bisphosphonate derivative as a powerful cytostatic and cytotoxic agent, with proapoptotic and antiangiogenic properties on human breast cancer cells lines, with no animal toxicity
ETUDE STRUCTURALE DU TÉTRAESTER MÉTHYLIQUE DE L'ACIDE ETHANE HYDROXY-1 DIPHOSPHONIQUE-1,1′ ET DU TETRAESTER MÉTHYLIQUE DE L'ACIDE MÉTHANE HYDROXY-1 PHÉNYL-1 DIPHOSPHONIQUE-1,1′
No full textETUDE STRUCTURALE DU COMPLEXE DE l′ACIDE ETHANE HYDROXY-1 DIPHOSPHONIQUE-1,1′ AVEC LE CUIVRE II
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