Synthesis of Regular Polyhexene in Perfluoromethylcyclohexane

This work was supported by the Russian Science Foundation (Ref. № 18-13-00365)

Synthesis of 5-Methyl-1,2,4-Triazolo[1,5-а]Pyrimidin-7(4H)-One-a Semi-Product of the Synthesis of Antiviral Drug Triazide® in the Conditions of Microwave Excitation

This work was supported by the Russian Science Foundation (Ref. № 18-13-00365)

QUANTITATIVE DETERMINATION OF VITAMINS A, D3 AND E IN PREMIXES «MAUERVIT» AND «GRANDVITAM» BY ULTRA HPLC

A convenient method for analyzing the content of vitamins A, D3 and E in premixes has been developed (the tests were carried out using the example of the premixes «Mauervit» and «randvitam») using ultra HPLC. The necessary changes of the procedure have been made in comparison with the ones presented previously in GOST R 50928-96 due to the presence in the premix components hampering analysis (in particular, Tween 80). The developed procedure has been tested in terms of specificity, accuracy and precision. In addition, the possibility of using a simpler procedure for the analysis of vitamins extract, used as raw material for premix production, has been demonstrated

METHOD OF DETERMINATION OF 5-METHYL-6-NITRO-7-OXO-1,2,4-TRIAZOLO[1,5-<i>a</i>]PIRIMIDINIDE <i>l-</i>ARGININY - THE ACTIVE COMPONENT OF DRUG «TRIAZID» BY HPLC METHOD

A procedure for quantitative determination of 5-methyl-6-nitro-7-oxo-1,2,4-triazolo[1,5-a]pirimidinide l -argininy was developed using the HPLC method with UV detection. To achieve the best chromatographic characteristics, it is proposed to use a column with a grafted octadecylsilyl phase 5-100-c18 (EKA, Sweden). The possibility of applying the developed procedure for the technological control of the third stage of the drug «Triazid» preparation was proved by the validation