Ethnobotanical study of Penchalakona forest area of Nellore District, Andhra Pradesh, India.

An ethno botanical survey was undertaken to collect information from yanadi tribe of penchalakona forest area, Rapur mandal, Nellore district, Andhra Pradesh, India.  The indigenous knowledge of traditional healers of this ethnic group has been disappearing due to lack of ancestors as well as followers. Only few people are practicing with little knowledge which was transmitted orally from their elders. The native plants used for medicinal purposes by few people were collected through questionnaire and personally interviewed during field trips. An aboriginal tribe called “Yanadi”, of this area has authentic information on medicinal values of different plant species.  Yanadi tribal community being drifted from their natural way of life due to agro rural development activities, a few aged persons are still able to furnish very little traditional ethno botanical data and continue to depend on medicinal plants atleast for the treatment of primary healthcare.  Because the area is located near the forest and 70 Kms from Nellore town.The study revealed that, the Yanadi tribe used 20 plants species belonging to 20 families to treat various diseases like worm infestations, scorpion stinge, headache, body pains, fevers, swelling of foots, skin diseases, heart diseases, stomach ulcers, diuretic, dysentery, snake bites, nerve disorders, rheumatic pains, antiseptic, helmentic disease, diabetes, cold and dental problems.These plants represents the major source for the pharmaceutical industries in view of their raw material. The information requires validation for further clinical usage

Performance Analysis of Block PSO for Image De-noising using Wavelet Transform

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Influence of plant growth regulators on growth, seed yield, quality and economics of coriander (Coriandrum sativum L.) cv. Sudha

A field experiment was conducted to study the effect of plant growth regulators (PGRs) on growth, seed yield, quality and economics of coriander (Coriandrum sativum L.) cv. Sudha. The seven treatments included in the experiment are two concentrations each of GA3 (50 and 75 ppm), NAA (10 and 25 ppm), Cycocel (100 and 250 ppm) and control (water spray), as presoaking, foliar spray at 30 and 60 DAS. Among different PGRs applied, spray of 75 ppm GA3 resulted in significant maximum plant height. However, maximum number of primary branches and secondary branches plant-1, number of umbels plant-1, number of umbellets umbel-1, number of seeds umbel-1, seed yield and B:C ratio was maximum with 250 ppm Cycocel. Minimum number of days to 50% flowering and maturity and maximum carbohydrate content and protein content were noticed with 75 ppm GA3. Similarly, lowest moisture content in seeds was also observed with 75 ppm GA3, while, the essential oil content in seeds was maximum with 50 ppm GA3. &nbsp

Selection of accessions from minicore to improve disease resistance in groundnut

A mini core subset of world germplasm comprising 188 accessions was evaluated for late leaf spot, rust and seed colonization by A. flavus. Accessions highly resistant to late leaf spot (ICG 2857, ICG 8760, ICG 12625, ICG 13787, ICG 12672, ICG 14475 and ICG 11426), rust (ICG 4746, ICG 6706, ICG 11088 and ICG 11426) and A. flavus (ICG 14985, ICG 6025, ICG 3673, ICG 12625, ICG 13787 and ICG 8760) were identified. Some accessions (ICG 12625, ICG 13787, ICG 11426 and ICG 8760) combined resistance to at least two diseases. The identified accessions along with three popular cultivars (GPBD 4, TAG 24 and JL 24) were subjected to RAPD assay using twenty primers to assess molecular diversity. The genetic similarity (Sij) ranged from 0.64 to 0.92. Accessions ICG 6706, 14475 and 8760 were more diverse with the popular varieties. The information generated in this study will be of great value to plant breeders in their effort to develop varieties resistant to fungal diseases through hybridization

Reliable identification of protein-protein interactions by crosslinking mass spectrometry

Protein-protein interactions govern most cellular pathways and processes, and multiple technologies have emerged to systematically map them. Assessing the error of interaction networks has been a challenge. Crosslinking mass spectrometry is currently widening its scope from structural analyses of purified multi-protein complexes towards systems-wide analyses of protein-protein interactions (PPIs). Using a carefully controlled large-scale analysis of Escherichia coli cell lysate, we demonstrate that false-discovery rates (FDR) for PPIs identified by crosslinking mass spectrometry can be reliably estimated. We present an interaction network comprising 590 PPIs at 1% decoy-based PPI-FDR. The structural information included in this network localises the binding site of the hitherto uncharacterised protein YacL to near the DNA exit tunnel on the RNA polymerase.TU Berlin, Open-Access-Mittel – 2021DFG, 390540038, EXC 2008: Unifying Systems in Catalysis "UniSysCat"DFG, 392923329, GRK 2473: Bioaktive Peptide - Innovative Aspekte zur Synthese und BiosyntheseDFG, 426290502, Erfassung der strukturellen Organisation des Mycoplasma pneumoniae Proteoms mittels in-Zell Crosslinking-Massenspektrometri

Efficient Construction of Azaspiro[4.5]trienone Libraries via Tandem Ugi 4CC/Electrophilic <i>ipso</i>-Iodocyclization in One-Pot

A solution-phase parallel synthesis of pharmaceutically important azaspiro[4.5]­trienones has been developed by performing tandem Ugi four-component condensation (U4CC), involving substituted <i>p</i>-anisidines, aldehydes, 3-alkyl/aryl-propiolic acids, and isocyanides, and iodine-mediated <i>ipso</i>-iodocyclization in one-pot. This highly atom economical process produced functionalized azaspiro[4.5]­trienones in good to excellent overall yields and products were easily isolated by precipitation followed by crystallization. These vinyl-iodide bearing azaspiro[4.5]­trienones were utilized for further modifications through Suzuki coupling and deiodination reaction to demonstrate the suitability of these products for various palladium catalyzed modifications. The present method provides an easy access to highly functionalized azaspiro[4.5]­trienones that can be useful in drug discovery research

Introgressions from Oryza rufipogon Increase Photosynthetic Efficiency of KMR3 Rice Lines

To understand the wild Oryza genome effect on photosynthesis and its relation to total dry matter accumulation in an elite rice variety, a set of 40 stable introgression lines (ILs) BC3F8 derived from a cross of Oryza sativa (KMR3) × Oryza rufipogon (WR120) were grown under well watered conditions. Leaf gas exchange measurements and leaf chlorophyll estimates were conducted at the flowering stage. The results revealed significant variations in net photosynthetic rate (Pn), transpiration rate (E), transpiration efficiency (Pn/E) and carboxylation efficiency (Pn/Ci). Pn showed significant positive correlation with E, stomatal conductance (gs), Pn/Ci and total canopy dry matter. Specific leaf area and leaf thickness were not significantly correlated with Pn. Thirty-seven out of 40 ILs showed higher Pn than KMR3 [11.28 μmol/(m2·s)], and 20 ILs showed higher Pn than WR120 [15.08 μmol/(m2·s)]. The line IL194 showed the highest Pn [21.62 μmol/(m2·s)] with increased total canopy dry matter followed by lines IL381, IL106, IL363-12, IL198, IL86-18 and IL50, which exhibited Pn above 18.0 μmol/(m2·s). The ILs with enhanced Pn are a potential source for developing rice varieties and hybrids with higher biomass and yield