Feed preference in pigs: Relationship between cereal preference and nutrient composition and digestibility

The present work aimed to identify the nutritional characteristics that best explain cereal feed preference in pigs. A total of 25 cereals of known preference (at 60% of inclusion in complete feed) from a previous study were evaluated. The cereals were analyzed for DM, OM, crude fiber, ether extract, CP, GE, digestible starch, and glycemic index. Additionally, for 12 of the cereals, complete feeds (the same composition as those previously used to measure preference) were prepared, analyzed for DM, OM, CP, and starch, and fed to pigs (33 ± 5.1 kg BW) fitted with ileal T-cannulae to assess the apparent ileal (AID) and total tract digestibility (ATTD) of these nutrients using titanium dioxide as an indigestible marker. The relationships among the different energy and nutrient contents were studied by principal component (PC) analysis, and the correlations between the generated PC scores and cereal preference were analyzed. A correlation between preference and the second PC obtained with data of the 25 cereals was observed (P < 0.01), which indicated that crude fiber (negatively) and digestible starch, OM, and glycemic index (positively) were correlated with feed preference. Statistically significant linear relationships with preference were confirmed for crude fiber, digestible starch, and glycemic index (R = 0.38, 0.36, and 0.23, respectively; P < 0.02). Similarly, the first PC obtained with data of the 12 feeds also correlated with preference (P < 0.01), indicating that the digestible nutrients (positively) and the nondigestible nutrients (negatively) were correlated with preference. Statistically significant relationships with preference were observed for the contents of starch (total, digestible AID, and digestible ATTD: R = 0.62, 0.66, and 0.63, respectively; P < 0.01), AID DM (digestible and nondigestible: R = 0.41 and 0.44, respectively; P < 0.05), ATTD DM (digestible and nondigestible: R = 0.67 and 0.70, respectively; P < 0.01), AID OM (digestible and nondigestible: R = 0.45 and 0.43, respectively; P < 0.05), and ATTD OM (digestible and nondigestible: R = 0.64 and 0.66, respectively;

Fish oil rich in eicosapentaenoic acid and docosahexaenoic acid in sow diets modifies oxylipins and immune indicators in colostrum and milk

Colostrum and milk are the first nutrient sources for newborn piglets. In addition, n-3 fatty acids (FAs) and their oxygenated derivatives (oxylipins) have the capacity to modulate immune components. The aim of the current study was to include a fish oil rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in sow diets to promote an increase of anti-inflammatory molecules in colostrum and milk to benefit piglets. Thirty-six sows were randomly assigned from insemination to the end of lactation to either a control diet with animal fat (15 g/kg in gestation and 30 g/kg in lactation) or an n-3 diet in which animal fat was totally (gestation) or half (lactation) replaced by an equivalent amount of solid fish oil. Performance of sows and piglets was monitored during the study. Colostrum and milk samples were obtained after the birth of the first piglet and at weaning, respectively. From all samples (n = 18 per treatment), FAs were quantified by gas chromatography and immunoglobulins and cytokines by ELISA. Three samples per treatment were randomly selected to analyse oxylipin composition by liquid chromatography-tandem mass spectrometry. In colostrum and in milk, the n-3 FA (P = 0.020 and P < 0.001), particularly EPA (P < 0.001 and P < 0.001) and DHA (P < 0.001 and P < 0.001), and also their oxygenated derivatives were increased in samples from sows fed n-3 diet. Fish oil had no effect on immunoglobulin concentrations, but reduced tumour necrosis factor α (TNFα) (P = 0.011) and a tendency to reduce interleukin 10 (IL10) (P = 0.059) were observed in milk. In conclusion, fish oil in sow diets increased n-3 FA, particularly EPA and DHA, and their oxygenated derivatives in colostrum and milk, reducing TNFα and IL10 in milk.info:eu-repo/semantics/publishedVersio

The potential for immunoglobulins and host defense peptides (HDPs) to reduce the use of antibiotics in animal production

Abstract Innate defense mechanisms are aimed at quickly containing and removing infectious microorganisms and involve local stromal and immune cell activation, neutrophil recruitment and activation and the induction of host defense peptides (defensins and cathelicidins), acute phase proteins and complement activation. As an alternative to antibiotics, innate immune mechanisms are highly relevant as they offer rapid general ways to, at least partially, protect against infections and enable the build-up of a sufficient adaptive immune response. This review describes two classes of promising alternatives to antibiotics based on components of the innate host defense. First we describe immunoglobulins applied to mimic the way in which they work in the newborn as locally acting broadly active defense molecules enforcing innate immunity barriers. Secondly, the potential of host defense peptides with different modes of action, used directly, induced in situ or used as vaccine adjuvants is described

The contribution of the gastrointestinal microflora to the amino acid requirements of non ruminants

SIGLEAvailable from British Library Document Supply Centre- DSC:DX181714 / BLDSC - British Library Document Supply CentreGBUnited Kingdo