56 research outputs found

    A convenient one-pot access to <i>N</i>-substituted pyrroles from nitro benzenes under neat aqueous conditions

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    1112-1116A practical and straightforward one-step procedure for the synthesis of N-functionalized pyrroles via reductive cyclization is described. The simple one-pot reaction is carried out by treating various substituted nitro benzenes with readily available building blocks 2,5-dimethoxytetrahydrofuran or γ-diketone in the presence of SnCl2 under aqueous conditions at 55°C
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