Advanced Membrane Devices. Interim Report for the Period October 1996--September 1997

Under this Cooperative Agreement, Air Products and Chemicals, Inc. has continued to investigate and develop improved membrane technology for removal of carbon dioxide from natural gas. The task schedule for this reporting period included a detailed assessment of the market opportunity (Chapter 2), continued development and evaluation of membranes and membrane polymers (Chapter 3) and a detailed economic analysis comparing the potential of Air Products membranes to that of established acid gas removal processes (Chapter 4)

Identification of potential chemoresistance genes in osteosarcoma

BACKGROUND: Osteosarcoma (OS) is an aggressive bone malignancy that primarily affects children and adolescents. Patients with metastatic disease at diagnosis have only a 20% survival rate. The poor survival rate of these patients is largely due to their lack of responsiveness to chemotherapy. However, the mechanisms underlying osteosarcoma chemoresistance remain unknown. MATERIALS AND METHODS: The effect of cisplatin, doxorubicin and etoposide was examined on OS cell lines. Affymetric Genechip analysis was used to examine differential gene expression. RESULTS: A correlation between increasing metastatic potential and increasing chemoresistance was observed in the MG-63 cell line and sub-line model. Microarray analysis of these cell lines revealed the differential expression of several genes potentially involved in chemoresistance including ABCG2, ADD3, NMT2, WNTSa and PTN. CONCLUSION: The identification of genes contributing to chemoresistance and determining the role these genes play is critical in characterizing patient responsiveness and overcoming chemoresistance in osteosarcoma patients

Attitudes toward Psychological Telehealth: Current and Future Clinical Psychologists’ Opinions of Internet‐Based Interventions

Objectives: The current study explored differences in acceptance of telehealth interventions amongst currently licensed and future clinicians with a focus on web camera-based intervention. The influence of theoretical orientation was also assessed. Method: An online survey assessed 717 participants comprising 409 licensed psychologists (40.8% female, mean age = 56.57, standard deviation [SD] = 11.01) and 308 doctoral-level students (78.9% female, mean age = 27.66, SD = 5.9) across domains of endorsement and rejection. Results: Binary logistic regression indicated no significant difference between currently licensed and future psychologists in their endorsement oftelehealth modalities. Cognitive-behavioral, cognitive, behavioral, and systems psychologists were significantly more accepting of telehealthinterventions than were dynamic/analytic or existential therapists. Conclusions: Increasing exposure to telehealth through education as well as continued research on efficacy for specific diagnoses may help psychologists to more effectively determine whether telehealth is the best fit for both clinician and client