75 research outputs found
Tick-borne lymphadenopathy (TIBOLA) acquired in Southwestern Germany
<p>Abstract</p> <p>Background</p> <p>Tick-borne lymphadenopathy (TIBOLA) was first described in 1997 in a patient in France. The causative agent, <it>Rickettsia slovaca</it>, is transmitted by <it>Dermacentor </it>ticks.</p> <p>Case presentation</p> <p>In southwestern Germany we encountered a patient with a tick bite at the dorsal scalp that resulted in an eschar and nuchal lymphadenopathy. Additionally, fever, malaise as well as elevated inflammatory markers and transaminases occurred. The characteristic clinical picture along with positive antibody testing for rickettsiae of the tick-borne spotted fever group strongly suggest the diagnosis TIBOLA.</p> <p>Conclusion</p> <p>Human rickettsioses are emerging infections. Clinicians should be aware of TIBOLA as a newly described rickettsial disease. As in our case, TIBOLA may be encountered in regions/countries where <it>R. slovaca </it>and <it>Dermacentor </it>ticks are prevalent but autochthonous acquisition was not described before.</p
Galaxy and Cluster Biasing from Local Group Dynamics
Comparing the gravitational acceleration induced on the Local Group of
galaxies by different tracers of the underline density field we estimate,
within the linear gravitational instability theory and the linear biasing
ansatz, their relative bias factors. Using optical SSRS2 galaxies, IRAS (PSCz)
galaxies and Abell/ACO clusters, we find b_{O,I} ~ 1.21 +- 0.06 and b_{C,I} ~
4.3 +- 0.8, in agreement with other recent studies. Finally, there is an
excellent one-to-one correspondence of the PSCz and Abell/ACO cluster dipole
profiles, once the latter is rescaled by b_{C,I}, out to at least ~150 h^{-1}
Mpc.Comment: 7 pages, 5 figures, accepted for publication in MNRA
Molecular Detection of Multiple Emerging Pathogens in Sputa from Cystic Fibrosis Patients
Background: There is strong evidence that culture-based methods detect only a small proportion of bacteria present in the respiratory tracts of cystic fibrosis (CF) patients. Methodology/Principal Findings: Standard microbiological culture and phenotypic identification of bacteria in sputa from CF patients have been compared to molecular methods by the use of 16S rDNA amplification, cloning and sequencing. Twenty-five sputa from CF patients were cultured that yield 33 isolates (13 species) known to be pathogens during CF. For molecular cloning, 760 clones were sequenced (7.263.9 species/sputum), and 53 different bacterial species were identified including 16 species of anaerobes (30%). Discrepancies between culture and molecular data were numerous and demonstrate that accurate identification remains challenging. New or emerging bacteria not or rarely reported in CF patients were detected including Dolosigranulum pigrum, Dialister pneumosintes, and Inquilinus limosus. Conclusions/Significance: Our results demonstrate the complex microbial community in sputa from CF patients, especially anaerobic bacteria that are probably an underestimated cause of CF lung pathology. Metagenomic analysis is urgentl
Canada and Aichi Biodiversity Target 11: understanding âother effective area-based conservation measuresâ in the context of the broader target
Irradiation of PMMA with high energy light ions the depth distribution for volatile reaction product emission
Implantation of polymers at medium ion fluences a spatial heterogeneity of radiation damage due to dominant electronic stopping
Forest management with multiple criteria and multiple stakeholders: An application to two public forests in Spain
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