546 research outputs found
Comments on alternative calculations of the broadening of spectral lines of neutral sodium by H-atom collisions
With the exception of the sodium D-lines recent calculations of line
broadening cross-sections for several multiplets of sodium by Leininger et al
(2000) are in substantial disagreement with cross-sections interpolated from
the tables of Anstee and O'Mara (1995) and Barklem and O'Mara (1997). The
discrepancy is as large as a factor of three for the 3p-4d multiplet. The two
theories are tested by using the results of each to synthesize lines in the
solar spectrum. It is found that generally the data from the theory of Anstee,
Barklem and O'Mara produce the best match to the observed solar spectrum. It is
found, using a simple model for reflection of the optical electron by the
potential barrier between the two atoms, that the reflection coefficient is too
large for avoided crossings with the upper states of subordinate lines to
contribute to line broadening, supporting the neglect of avoided ionic
crossings by Anstee, Barklem and O'Mara for these lines. The large
discrepancies between the two sets of calculations is a result of an
approximate treatment of avoided ionic crossings for these lines by Leininger
et al (2000).Comment: 18 pages, 5 ps figures included, to appear in J Phys B: At. Mol. Opt.
Phy
Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice
Cell death by apoptosis has a critical role during embryonic development and in maintaining tissue homeostasis. In mammals,
there are two converging apoptosis pathways: the ‘extrinsic’ pathway, which is triggered by engagement of cell surface ‘death
receptors’ such as Fas/APO-1; and the ‘intrinsic’ pathway, which is triggered by diverse cellular stresses, and is regulated by prosurvival
and pro-apoptotic members of the Bcl-2 family of proteins. Pro-survival Mcl-1, which can block activation of the proapoptotic
proteins, Bax and Bak, appears critical for the survival and maintenance of multiple haemopoietic cell types. To
investigate the impact on haemopoiesis of simultaneously inhibiting both apoptosis pathways, we introduced the vavP-Mcl-1
transgene, which causes overexpression of Mcl-1 protein in all haemopoietic lineages, into Faslpr/lpr mice, which lack functional
Fas and are prone to autoimmunity. The combined mutations had a modest impact on myelopoiesis, primarily an increase in the
macrophage/monocyte population in Mcl-1tg/lpr mice compared with lpr or Mcl-1tg mice. The impact on lymphopoiesis was
striking, with a marked elevation in all major lymphoid subsets, including the non-conventional double-negative (DN) T cells
(TCRβ+
CD4–
CD8–
B220+
) characteristic of Faslpr/lpr mice. Of note, the onset of autoimmunity was markedly accelerated in Mcl-1tg/lpr
mice compared with lpr mice, and this was preceded by an increase in immunoglobulin (Ig)-producing cells and circulating
autoantibodies. This degree of impact was surprising, given the relatively mild phenotype conferred by the vavP-Mcl-1 transgene
by itself: a two- to threefold elevation of peripheral B and T cells, no significant increase in the non-conventional DN T-cell
population and no autoimmune disease. Comparison of the phenotype with that of other susceptible mice suggests that the
development of autoimmune disease in Mcl-1tg/lpr mice may be influenced not only by Ig-producing cells but also other
haemopoietic cell types
A method for the direct demonstration of the lectin-binding components of the human erythrocyte membrane
The membrane change in En(a-) human erythrocytes. Absence of the major erythrocyte sialoglycoprotein
The Wrb antigen, a receptor for Plasmodium falciparum malaria, is located on a helical region of the major membrane sialoglycoprotein of human red blood cells
Isolation and characterization of the major oligosaccharide of human platelet membrane glycoprotein GPIb
Improved Laboratory Transition Probabilities for Neutral Chromium and Re-determination of the Chromium Abundance for the Sun and Three Stars
Branching fraction measurements from Fourier transform spectra in conjunction
with published radiative lifetimes are used to determine transition
probabilities for 263 lines of neutral chromium. These laboratory values are
employed to derive a new photospheric abundance for the Sun: log (Cr
I) = 5.640.01 (). These Cr I solar abundances do
not exhibit any trends with line strength nor with excitation energy and there
were no obvious indications of departures from LTE. In addition, oscillator
strengths for singly-ionized chromium recently reported by the FERRUM Project
are used to determine: log (Cr II) = 5.770.03 (). Transition probability data are also applied to the spectra of three
stars: HD 75732 (metal-rich dwarf), HD 140283 (metal-poor subgiant), and CS
22892-052 (metal-poor giant). In all of the selected stars, Cr I is found to be
underabundant with respect to Cr II. The possible causes for this abundance
discrepancy and apparent ionization imbalance are discussed.Comment: 44 pages, 6 figure
A carbohydrate-deficient membrane glycoprotein in human erythrocytes of phenotype S-s-
cDNA cloning of a 30 kDa erythrocyte membrane protein associated with Rh (Rhesus)-blood-group-antigen expression
Stellar Iron Abundances: non-LTE Effects
We report new statistical equilibrium calculations for Fe I and Fe II in the
atmosphere of Late-Type stars. We used atomic models for Fe I and Fe II having
respectively 256 and 190 levels, as well as 2117 and 3443 radiative
transitions. Photoionization cross-sections are from the Iron Project. These
atomic models were used to investigate non-LTE effects in iron abundances of
Late-Type stars with different atmospheric parameters.
We found that most Fe I lines in metal-poor stars are formed in conditions
far from LTE. We derived metallicity corrections of about 0.3 dex with respect
to LTE values, for the case of stars with [Fe/H] ~ -3.0. Fe II is found not to
be affected by significant non-LTE effects. The main non-LTE effect invoked in
the case of Fe I is overionization by ultraviolet radiation, thus classical
ionization equilibrium is far to be satisfied. An important consequence is that
surface gravities derived by LTE analysis are in error and should be corrected
before final abundances corrections.
This apparently solves the observed discrepancy between spectroscopic surface
gravities derived by LTE analyses and those derived from Hipparcos parallaxes.
A table of non-LTE [Fe/H] and log g values for a sample of metal-poor late-type
stars is given.Comment: 22 pages, 9 figures, 1 table, ApJ style, accepte
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