2,164 research outputs found
Current-Induced Spin Polarization in Gallium Nitride
Electrically generated spin polarization is probed directly in bulk GaN using
Kerr rotation spectroscopy. A series of n-type GaN epilayers are grown in the
wurtzite phase both by molecular beam epitaxy (MBE) and metalorganic chemical
vapor deposition (MOCVD) with a variety of doping densities chosen to broadly
modulate the transverse spin lifetime, T2*. The spin polarization is
characterized as a function of electrical excitation energy over a range of
temperatures. Despite weak spin-orbit interactions in GaN, a current-induced
spin polarization (CISP) is observed in the material at temperatures of up to
200 K.Comment: 16 pages, 3 figure
Alkylation of deoxyribonucleic acid by carcinogens dimethyl sulphate, ethyl methanesulphonate, N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea. Relative reactivity of the phosphodiester site thymidylyl(3′-5′)thymidine
Epidemiological patterns of hepatitis B virus (HBV) in highly endemic areas
This paper uses meta-analysis of published data and a deterministic mathematical model of hepatitis B virus (HBV) transmission to describe the patterns of HBV infection in high endemicity areas. We describe the association between the prevalence of carriers and a simple measure of the rate of infection, the age at which half the population have been infected (A50), and assess the contribution of horizontal and perinatal transmission to this association. We found that the two main hyper-endemic areas of sub-Saharan Africa and east Asia have similar prevalences of carriers and values of A50, and that there is a negative nonlinear relationship between A50 and the prevalence of carriers in high endemicity areas (Spearman's Rank, P = 0·0086). We quantified the risk of perinatal transmission and the age-dependent rate of infection to allow a comparison between the main hyper-endemic areas. East Asia was found to have higher prevalences of HBeAg positive mothers and a greater risk of perinatal transmission from HBeAg positive mothers than sub-Saharan Africa, though the differences were not statistically significant. However, the two areas have similar magnitudes and age-dependent rates of horizontal transmission. Results of a simple compartmental model suggest that similar rates of horizontal transmission are sufficient to generate the similar patterns between A50 and the prevalences of carriers. Interrupting horizontal transmission by mass immunization is expected to have a significant, nonlinear impact on the rate of acquisition of new carriers
Kirchhoff's Loop Law and the maximum entropy production principle
In contrast to the standard derivation of Kirchhoff's loop law, which invokes
electric potential, we show, for the linear planar electric network in a
stationary state at the fixed temperature,that loop law can be derived from the
maximum entropy production principle. This means that the currents in network
branches are distributed in such a way as to achieve the state of maximum
entropy production.Comment: revtex4, 5 pages, 2 figure
Activation of p34cdc2 kinase by cyclin A
Functional clam cyclin A and B proteins have been produced using a baculovirus expression system. Both cyclin A and B can induce meiosis I and meiosis II in Xenopus in the absence of protein synthesis. Half-maximal induction occurs at 50 nM for cyclin A and 250 nM for cyclin B. Addition of 25 nM cyclin A to activated Xenopus egg extracts arrested in the cell cycle by treatment with RNase or emetine activates cdc2 kinase to the normal metaphase level and stimulates one oscillatory cell cycle. High levels of cyclin A cause marked hyperactivation of cdc2 kinase and a stable arrest at the metaphase point in the cell cycle. Kinetic studies demonstrate the concentration of cyclin A added does not affect the 10 min lag period required for kinase activation or the timing of maximal activity, but does control the rate of deactivation of cdc2 kinase during exit from mitosis. In addition, exogenous clam cyclin A inhibits the degradation of both A- and B-type endogenous Xenopus cyclins. These results define a system for investigating the biochemistry and regulation of cdc2 kinase activation by cyclin A
Arago (1810): the first experimental result against the ether
95 years before Special Relativity was born, Arago attempted to detect the
absolute motion of the Earth by measuring the deflection of starlight passing
through a prism fixed to the Earth. The null result of this experiment gave
rise to the Fresnel's hypothesis of an ether partly dragged by a moving
substance. In the context of Einstein's Relativity, the sole frame which is
privileged in Arago's experiment is the proper frame of the prism, and the null
result only says that Snell's law is valid in that frame. We revisit the
history of this premature first evidence against the ether theory and calculate
the Fresnel's dragging coefficient by applying the Huygens' construction in the
frame of the prism. We expose the dissimilar treatment received by the ray and
the wave front as an unavoidable consequence of the classical notions of space
and time.Comment: 16 pages. To appear in European Journal of Physic
Influence of amount and percentage of CXCR4-using virus in predicting week 48 responses to maraviroc in treatment-naïve patients
Elastic Constants of Quantum Solids by Path Integral Simulations
Two methods are proposed to evaluate the second-order elastic constants of
quantum mechanically treated solids. One method is based on path-integral
simulations in the (NVT) ensemble using an estimator for elastic constants. The
other method is based on simulations in the (NpT) ensemble exploiting the
relationship between strain fluctuations and elastic constants. The strengths
and weaknesses of the methods are discussed thoroughly. We show how one can
reduce statistical and systematic errors associated with so-called primitive
estimators. The methods are then applied to solid argon at atmospheric
pressures and solid helium 3 (hcp, fcc, and bcc) under varying pressures. Good
agreement with available experimental data on elastic constants is found for
helium 3. Predictions are made for the thermal expectation value of the kinetic
energy of solid helium 3.Comment: 9 pages doublecolumn, 6 figures, submitted to PR
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