Discovery of the lensed quasar eRASS1 J050129.5-073309 with SRG/\textit{SRG}/eROSITA and Gaia{\it Gaia}

We report the discovery and spectroscopic identification of the bright doubly lensed quasar eRASS1 J050129.5-073309 at redshift $z=2.47$, selected from the first all-sky survey of the ${\it Spectrum\; Roentgen\; Gamma\; (SRG)}$ eROSITA telescope and the ${\it Gaia}$ EDR3 catalog. We systematically search for extragalactic sources with eROSITA X-ray positions having multiple ${\it Gaia}$ counterparts and have started spectroscopic follow-up of the most promising candidates using long-slit spectroscopy with NTT/EFOSC2 to confirm the lens nature. The two images are separated by $2.7''$ and their average ${\it Gaia}$ ${\it g}$-band magnitudes are 16.95 and 17.33. Legacy Survey DR10 imaging and image modeling reveal both the lensing galaxy and tentatively the lensed image of the quasar host galaxy. Archival optical light curves show evidence of a variability time delay with the fainter component lagging the brighter by about 100 days. The fainter image has also decreased its brightness by about 1 magnitude since 2019. This dimming was still obvious at the time of the spectroscopic observations and is probably caused by microlensing. The optical spectroscopic follow-up obtained from NTT/EFOSC2 and the evidence provided by the imaging and timing analysis allow us to confirm the lensed nature of eRASS1 J050129.5-073309.Comment: Accepted for publication in A&

The Subaru Coronagraphic Extreme Adaptive Optics system: enabling high-contrast imaging on solar-system scales

The Subaru Coronagraphic Extreme Adaptive Optics (SCExAO) instrument is a multipurpose high-contrast imaging platform designed for the discovery and detailed characterization of exoplanetary systems and serves as a testbed for high-contrast imaging technologies for ELTs. It is a multi-band instrument which makes use of light from 600 to 2500nm allowing for coronagraphic direct exoplanet imaging of the inner 3 lambda/D from the stellar host. Wavefront sensing and control are key to the operation of SCExAO. A partial correction of low-order modes is provided by Subaru's facility adaptive optics system with the final correction, including high-order modes, implemented downstream by a combination of a visible pyramid wavefront sensor and a 2000-element deformable mirror. The well corrected NIR (y-K bands) wavefronts can then be injected into any of the available coronagraphs, including but not limited to the phase induced amplitude apodization and the vector vortex coronagraphs, both of which offer an inner working angle as low as 1 lambda/D. Non-common path, low-order aberrations are sensed with a coronagraphic low-order wavefront sensor in the infrared (IR). Low noise, high frame rate, NIR detectors allow for active speckle nulling and coherent differential imaging, while the HAWAII 2RG detector in the HiCIAO imager and/or the CHARIS integral field spectrograph (from mid 2016) can take deeper exposures and/or perform angular, spectral and polarimetric differential imaging. Science in the visible is provided by two interferometric modules: VAMPIRES and FIRST, which enable sub-diffraction limited imaging in the visible region with polarimetric and spectroscopic capabilities respectively. We describe the instrument in detail and present preliminary results both on-sky and in the laboratory.Comment: Accepted for publication, 20 pages, 10 figure

Low-lying quadrupole collective states of the light and medium Xenon isotopes

Collective low lying levels of light and medium Xenon isotopes are deduced from the Generalized Bohr Hamiltonian (GBH). The microscopic seven functions entering into the GBH are built from a deformed mean field of the Woods-Saxon type. Theoretical spectra are found to be close to the ones of the experimental data taking into account that the calculations are completely microscopic, that is to say, without any fitting of parameters.Comment: 8 pages, 4 figures, 1 tabl

Central radio galaxies in galaxy clusters: Joint surveys by eROSITA and ASKAP

The extended ROentgen Survey with an Imaging Telescope Array (eROSITA) telescope onboard the Spectrum-Roentgen-Gamma (SRG) mission has finished the first eROSITA All-Sky Survey (eRASS:1), and detected 10$^4$ galaxy clusters in the western Galactic hemisphere. In the radio band, the Australian Square Kilometre Array Pathfinder (ASKAP) telescope finished its pilot 1 phase of the project 'Evolutionary Map of the Universe' (EMU) with 220.000 sources in a 270 deg$^2$ field overlapping with eRASS:1. These two surveys are used to study radio-mode Active Galactic Nuclei (AGN) in clusters. In order to understand the efficiency of radio-mode feedback at the centers of galaxy clusters, we relate the radio properties of brightest cluster galaxies (BCG) to the X-ray properties of the host clusters. We identify the central radio sources in eRASS:1 clusters or calculate corresponding upper limits on the radio luminosity. Then, we derive relations between the X-ray properties of the clusters and the radio properties of the corresponding central radio source. We also apply a mid-infrared color criterion using WISE colors to identify AGN. In total we investigate a sample of 75 clusters. We find a statistically significant correlation between the X-ray luminosity of the cluster and the 944 MHz radio luminosity of the corresponding central radio galaxy. There is also a positive trend between the radio power and the largest linear size (LLS) of the radio source. The density and the LLS do not show any correlation. We find that in high luminosity clusters with L_X > $10^{43}$ erg s$^{-1}$ the kinetic luminosity of the radio jets is not longer correlated with the X-ray luminosity and discuss various reasons. We find an anti-correlation between the central cooling time t_cool and the radio luminosity L_R indicating a need for more powerful AGN in clusters with short central cooling times.Comment: 16 pages, 12 figures, accepted for publication in A&

Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with type 2 diabetes with and without fatty liver

To investigate the potential of therapies which reduce glucocorticoid action in patients with Type 2 diabetes we performed a randomized, double-blinded, placebo-controlled crossover study of acute glucocorticoid blockade, using the glucocorticoid receptor antagonist RU38486 (mifepristone) and cortisol biosynthesis inhibitor (metyrapone), in 14 men with Type 2 diabetes. Stable isotope dilution methodologies were used to measure the rates of appearance of glucose, glycerol, and free fatty acids (FFAs), including during a low-dose (10 mU·m −2·min−1) hyperinsulinemic clamp, and subgroup analysis was conducted in patients with high or low liver fat content measured by magnetic resonance spectroscopy (n = 7/group). Glucocorticoid blockade lowered fasting glucose and insulin levels and improved insulin sensitivity of FFA and glycerol turnover and hepatic glucose production. Among this population with Type 2 diabetes high liver fat was associated with hyperinsulinemia, higher fasting glucose levels, peripheral and hepatic insulin resistance, and impaired suppression of FFA oxidation and FFA and glycerol turnover during hyperinsulinemia. Glucocorticoid blockade had similar effects in those with and without high liver fat. Longer term treatments targeting glucocorticoid action may be useful in Type 2 diabetes with and without fatty liver

Glutamine supplementation

Intravenous glutamine supplementation is standard care when parenteral nutrition is given for critical illness. There are data of a reduced mortality when glutamine supplementation is given. In addition, standard commercial products for parenteral nutrition do not contain any glutamine due to glutamine instability in aqueous solutions. For the majority of critical ill patients who are fed enterally, the available evidence is insufficient to recommend glutamine supplementation. Standard formulation of enteral nutrition contains some glutamine: 2-4 g/L. However, this dose is insufficient to normalize glutamine plasma concentration