28 research outputs found
Staphyliniden-Larven beeinflussen chemisch das Orientierungsverhalten ihrer Konkurrenten
Geruchsorientierung einer parasitischen K�ferlarve (Aleochara curtula Goeze) am Puparium des Wirtes (Calliphora)
Immunofluorescence studies for myosin, a- actinin and tropomyosin in developing hearts of normal and cardiac lethal mutant Mexican axolotls, Ambystoma mexicanum
Laboratory method for testing side-effects of pesticides on the rove beetleAleochara bilineata — Adults
Experimental analysis of the morphogenetic functions of the ectoderm during development of the external form of the chick embryo
Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment.
Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment.
Nerve growth factor-induced differentiation of adrenal chromaffin PC-12 cells to a neuronal phenotype involves alterations in gene expression and represents a model system to study neuronal differentiation. We have used the expressed-sequence-tag approach to identify approximately 600 differentially expressed mRNAs in untreated and nerve growth factor-treated PC-12 cells that encode proteins with diverse structural and biochemical functions. Many of these mRNAs encode proteins belonging to cellular pathways not previously known to be regulated by nerve growth factor. Comparative expressed-sequence-tag analysis provides a basis for surveying global changes in gene-expression patterns in response to biological signals at an unprecedented scale, is a powerful tool for identifying potential interactions between different cellular pathways, and allows the gene-expression profiles of individual genes belonging to a particular pathway to be followed