15,620 research outputs found

    Differential processing of plasma-ANF in cardiovascular disease

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    Curved Graphene Nanoribbons: Structure and Dynamics of Carbon Nanobelts

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    Carbon nanoribbons (CNRs) are graphene (planar) structures with large aspect ratio. Carbon nanobelts (CNBs) are small graphene nanoribbons rolled up into spiral-like structures, i. e., carbon nanoscrolls (CNSs) with large aspect ratio. In this work we investigated the energetics and dynamical aspects of CNBs formed from rolling up CNRs. We have carried out molecular dynamics simulations using reactive empirical bond-order potentials. Our results show that similarly to CNSs, CNBs formation is dominated by two major energy contribution, the increase in the elastic energy due to the bending of the initial planar configuration (decreasing structural stability) and the energetic gain due to van der Waals interactions of the overlapping surface of the rolled layers (increasing structural stability). Beyond a critical diameter value these scrolled structures can be even more stable (in terms of energy) than their equivalent planar configurations. In contrast to CNSs that require energy assisted processes (sonication, chemical reactions, etc.) to be formed, CNBs can be spontaneously formed from low temperature driven processes. Long CNBs (length of āˆ¼\sim 30.0 nm) tend to exhibit self-folded racket-like conformations with formation dynamics very similar to the one observed for long carbon nanotubes. Shorter CNBs will be more likely to form perfect scrolled structures. Possible synthetic routes to fabricate CNBs from graphene membranes are also addressed

    Biases in Illumina transcriptome sequencing caused by random hexamer priming

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    Generation of cDNA using random hexamer priming induces biases in the nucleotide composition at the beginning of transcriptome sequencing reads from the Illumina Genome Analyzer. The bias is independent of organism and laboratory and impacts the uniformity of the reads along the transcriptome. We provide a read count reweighting scheme, based on the nucleotide frequencies of the reads, that mitigates the impact of the bias

    Recursive deconvolution of combinatorial chemical libraries.

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    Chemotactic Collapse and Mesenchymal Morphogenesis

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    We study the effect of chemotactic signaling among mesenchymal cells. We show that the particular physiology of the mesenchymal cells allows one-dimensional collapse in contrast to the case of bacteria, and that the mesenchymal morphogenesis represents thus a more complex type of pattern formation than those found in bacterial colonies. We finally compare our theoretical predictions with recent in vitro experiments

    Shock waves in ultracold Fermi (Tonks) gases

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    It is shown that a broad density perturbation in a Fermi (Tonks) cloud takes a shock wave form in the course of time evolution. A very accurate analytical description of shock formation is provided. A simple experimental setup for the observation of shocks is discussed.Comment: approx. 4 pages&figures, minor corrections^2, to be published as a Letter in Journal of Physics

    Using participatory design and visual narrative inquiry to investigate researchersā€™ data challenges and recommendations for library research data services

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    Purpose ā€“ The purpose of this paper is to report on an information gathering study on usersā€™ research data-related challenges and proposals for library research data services (RDS). This study probes how early career researchers visually conceptualize the research process in their disciplines, their self-reported research data challenges, and their recommendations for library RDS. Design/methodology/approach ā€“ Two focus group sessions were undertaken with a total of eight early career researchers. Adopting the visual narrative inquiry method, the participants were asked to sketch the general research process in their domain. The individualsā€™ illustrations of the research process were then used as the basis for reflecting on their data-related needs and potential RDS that would assist them during the research process. Findings ā€“ Participants presented a research process that was more personal and, in most cases, more imperfect than the research lifecycle models that academic libraries are increasingly using for RDS development and communication. The authors present their data-related challenges, which included data access barriers, low knowledge of best practices for research data management, the need for a deeper understanding of post-publication impact, and inconsistent awareness of existing library and institution RDS. The authors outline RDS recommendations that participants proposed, which included a web-based tools, customized training sessions, and ā€œdistilledā€ guides to research data best practices. Practical implications ā€“ The study flagged usersā€™ gaps in understandings of existing library and institutional RDS, suggesting that there may be an opportunity to engage users in the design of communications plans for services. The findings from this user study will inform the development of RDS at the institution. Originality/value ā€“ This paper puts forth a methodological approach that academic libraries can adapt for understanding usersā€™ needs and user-generated design solutions

    The Two Fluid Drop Snap-off Problem: Experiments and Theory

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    We address the dynamics of a drop with viscosity Ī»Ī·\lambda \eta breaking up inside another fluid of viscosity Ī·\eta. For Ī»=1\lambda=1, a scaling theory predicts the time evolution of the drop shape near the point of snap-off which is in excellent agreement with experiment and previous simulations of Lister and Stone. We also investigate the Ī»\lambda dependence of the shape and breaking rate.Comment: 4 pages, 3 figure

    Consequences of wall stiffness for a beta-soft potential

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    Modifications of the infinite square well E(5) and X(5) descriptions of transitional nuclear structure are considered. The eigenproblem for a potential with linear sloped walls is solved. The consequences of the introduction of sloped walls and of a quadratic transition operator are investigated.Comment: RevTeX 4, 8 pages, as published in Phys. Rev.

    Arrested phase separation in reproducing bacteria: a generic route to pattern formation?

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    We present a generic mechanism by which reproducing microorganisms, with a diffusivity that depends on the local population density, can form stable patterns. It is known that a decrease of swimming speed with density can promote separation into bulk phases of two coexisting densities; this is opposed by the logistic law for birth and death which allows only a single uniform density to be stable. The result of this contest is an arrested nonequilibrium phase separation in which dense droplets or rings become separated by less dense regions, with a characteristic steady-state length scale. Cell division mainly occurs in the dilute regions and cell death in the dense ones, with a continuous flux between these sustained by the diffusivity gradient. We formulate a mathematical model of this in a case involving run-and-tumble bacteria, and make connections with a wider class of mechanisms for density-dependent motility. No chemotaxis is assumed in the model, yet it predicts the formation of patterns strikingly similar to those believed to result from chemotactic behavior
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