25 research outputs found
Etude in vido de l'affinité pour les récepteurs à mannose des macrophages, de polymères de dextranes substitués par des sucres par compétition avec la flucose oxydase. Abstract 6èmes Journées Scientifiques du G.T.R.V. - Montpellier (France) dec. 1991, p. 74.
No full textGLUCOSE-OXIDASE AS A TOOL TO STUDY IN-VIVO THE INTERACTION OF GLYCOSYLATED POLYMERS WITH THE MANNOSE RECEPTOR OF MACROPHAGES.
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Synthesis of polyglutamine and dextran conjugates of streptomycin with an acid-sensitive drug-carrier linkage.
No full textIdentifiability and estimation of pharmacokinetic parameters for the ligands of the macrophage mannose receptor
No full textThe aim of this paper is numerical estimation of pharmacokinetic parameters of the ligands of the macrophage mannose receptor, without knowing a priori the values of these parameters. However, it first requires a model identifiability analysis, which is done by applying an algorithm implemented in a symbolic computation language. It is shown that this step can lead to a direct numerical estimation algorithm. In this way, a first estimate is computed from noisy simulated observations without a priori parameter values. Then the resulting parameter estimate is improved by using the classical least-squares method
Radiation grafting of N-vinylpyrrolidone into silicone tubes. Synthesis of polymers with improved hemocompatibility and implantation tests in lambs
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Macromolecular prodrugs and molecular microencapsulation of antibiotics: Activity against INH-insensitive Mycobacterium bovis BCG present in the physiologically hypoxic mouse
No full textIn vivo efficiency of targeted norfloxacin against persistent, isoniazid-insensitive, Mycobacterium bovis BCG present in the physiologically hypoxic mouse liver
No full textPotential of glycosylated polymers for drug targeting. Abstract, Synthetic Polymers as drug carriers. Interactions with blood, 21-24 april 1991, Pallanza, (Italy), 165-168.
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