Local Spatio-Temporal Representation Using the 3D Shearlet Transform (STSIP)

In this work we address the problem of analyzing video sequences and of representing meaningful space-time points of interest by using the 3D shearlet transform. We introduce a local representation based on shearlet coe cients of the video, regarded as 2D+T signal. This representation turns out to be informative to understand the local spatio-temporal characteristics, which can be easily detected by an unsupervised clustering algorithm

Emergency Department Overcrowding. A Retrospective Spatial Analysis and the Geocoding of Accesses. A Pilot Study in Rome

The overcrowding of first aid facilities creates considerable hardship and problems which have repercussions on patients’ wellbeing, the time needed for a diagnosis, and on the quality of the assistance. The basic objective of this contribution, based on the data collected by the Hospital Policlinico Umberto I in Rome (Lazio region, Italy), is to carry out a territorial screening of the municipality using GIS applications and spatial analyses aimed at reducing—in terms of triage—code white (inappropriate) attendances, after having identified the areas of greatest provenance of improperly used emergency room access. Working in a GIS environment and using functions for geocoding, we have tested an experimental model aimed at giving a close-up geographical-sanitary look at the situation: recognizing the territorial sectors in Rome which contribute to amplifying the Policlinico Umberto I emergency room overcrowding; leading up to an improvement of the situation; promoting greater awareness and knowledge of the services available on the territory, a closer relationship between patient and regular doctor (general practitioner, GP) or Local Healthcare Unit and a more efficient functioning of the emergency room. In particular, we have elaborated a “source” map from which derive all the others and it is a dot map on which all the codes white have been geolocalized on a satellite image through geocoding. We have produced three sets made up of three digital cartographic elaborations each, constructed on the census sections, the census areas and the sub-municipal areas, according to data aggregation, for absolute and relative values, and using different templates. Finally, following the same methodology and steps, we elaborated another dot map about all the codes red to provide another kind of information and input for social utility. In the near future, this system could be tested on a platform that spatially analyzes the emergency department (ED) accesses in near-real-time in order to facilitate the identification of critical territorial issues and intervene in a shorter time to regulate the influx of patients to the ED

The evolutionary status of the white dwarf companion of the binary pulsar PSR J1713+0747

Splaver and coworkers have measured the masses of the white dwarf and the neutron star components of the PSR J1713+0747 binary system pair by Shapiro Delay. We attempt to find the original configuration of this system performing a set of binary evolution calculations to simultaneously account for the masses of both stars and the orbital period. We considered initial masses of 1.5 and 1.4 \msun for the normal (donor) and the neutron star, respectively. We assumed two metallicity values (Z = 0.010 and 0.020), and an initial orbital period near 3 days. We assume that the neutron star is only able to retain \lesssim 0.10 of the matter transferred by the donor star. Calculations were performed employing our binary hydro code that handles the mass transfer rate in a fully implicit way together with state-of-the-art physical ingredients, diffusion and a non-grey atmospheres. We compare the structure of the resulting white dwarfs with the characteristic age of PSR J1713+0747 finding a nice agreement with observations by Lundgren et al. especially for the case of a donor star with Z= 0.010. This result indicates that the evolution of this kind of binary system is well understood. The models predict that, due to diffusion, the atmosphere of the white dwarf is an almost hydrogen-pure one. We find that such structures are unable to account for the colours measured by Lundgren et al. within their error bars. Thus, some discrepances in the white dwarf emergent radiation remain to be explained

Genomics knowledge and attitudes among European public health professionals. Results of a cross-sectional survey

Background The international public health (PH) community is debating the opportunity to incorporate genomic technologies into PH practice. A survey was conducted to assess attitudes of the European Public Health Association (EUPHA) members towards their role in the implementation of public health genomics (PHG), and their knowledge and attitudes towards genetic testing and the delivery of genetic services. Methods EUPHA members were invited via monthly newsletter and e-mail to take part in an online survey from February 2017 to January 2018. A descriptive analysis of knowledge and attitudes was conducted, along with a univariate and multivariate analysis of their determinants. Results Five hundred and two people completed the questionnaire, 17.9% were involved in PHG activities. Only 28.9% correctly identified all medical conditions for which there is (or not) evidence for implementing genetic testing; over 60% thought that investing in genomics may divert economic resources from social and environmental determinants of health. The majority agreed that PH professionals may play different roles in incorporating genomics into their activities. Better knowledge was associated with positive attitudes towards the use of genetic testing and the delivery of genetic services in PH (OR = 1.48; 95% CI 1.01–2.18). Conclusions Our study revealed quite positive attitudes, but also a need to increase awareness on genomics among European PH professionals. Those directly involved in PHG activities tend to have a more positive attitude and better knowledge; however, gaps are also evident in this group, suggesting the need to harmonize practice and encourage greater exchange of knowledge among professionals

Polychrome majolica of Apulian domes: history, technique, pathology and conservation

The paper is focused on the historical-architectural evolution and material-technical qualification of polychrome majolica domes that were built between the 17th and 19th centuries in Apulian religious buildings. In particular, the cultural context in which this solution spread throughout the Mediterranean area is identified. Moreover, the case history of construction and decorative techniques that are distinctive of the regional territory is discussed in terms of underlying structure, installation of elements and surface colours. The study is then detailed on the Church of Santa Maria della Vetrana in Castellana Grotte (BA), for which the morpho-typological survey and mapping of the decay state are presented, based on the use of terrestrial and aerial digital photogrammetry. Finally, based on the identification of the main pathologies from both direct and indirect alteration factors, the most appropriate conservation and maintenance interventions are outlined, with specific focus on repair and integration of the majolica tiles, according to principles of high compatibility and low intrusiveness for a solution meeting artisan tradition and technical practice

VDAC1 is a transplasma membrane NADH: ferricyanide reductase

Porin isoform 1 or VDAC (voltage-dependent anion-selective channel) 1 is the predominant protein in the outer mitochondrial membrane. We demonstrated previously that a plasma membrane NADH-ferricyanide reductase activity becomes up-regulated upon mitochondrial perturbation, and therefore suggested that it functions as a cellular redox sensor. VDAC1 is known to be expressed in the plasma membrane; however, its function there remained a mystery. Here we show that VDAC1, when expressed in the plasma membrane, functions as a NADH-ferricyanide reductase. VDAC1 preparations purified from both plasma membrane and mitochondria fractions exhibit NADH-ferricyanide reductase activity, which can be immunoprecipitated with poly- and monoclonal antibodies directed against VDAC(1). Transfecting cells with pl-VDAC1-GFP, which carries an N-terminal signal peptide, directs VDAC1 to the plasma membrane, as shown by confocal microscopy and FACS analysis, and significantly increases the plasma membrane NADH-ferricyanide reductase activity of the transfected cells. This novel enzymatic activity of the well known VDAC1 molecule may provide an explanation for its role in the plasma membrane. Our data suggest that a major function of VDAC1 in the plasma membrane is that of a NADH(-ferricyanide) reductase that may be involved in the maintenance of cellular redox homeostasis