Scintillation proportional Xe counter with WLS fiber readout for low-energy X-rays

A gas Xe based scintillation proportional counter with cylindrical geometry and wavelength shifting (WLS) fiber readout for X-rays of energy 0.5 - 100 keV is proposed. With such a design large sizes and sensitive area of the counter with a fairly well uniformity is possible. The counter could be used for "dark matter" search and neutrino magnetic moment measurement and for detection of small amounts or traces of radioactive elements in substances or environment.Comment: LaTeX 4 pages, 3 figures in eps, Submitted to NI

Chemosensor for micro to nano-molar detection of Ag+ and Hg2+ ions in pure aqueous media and its applications in cell imaging

The pyridine substituted thiourea derivative PTB-1 was synthesized and characterized by spectroscopic techniques as well as by single crystal X-ray crystallography. The metal ion sensing ability of PTB-1 was explored by various experimental (naked-eye, UV-Vis, fluorescence, mass spectrometry and 1H NMR spectroscopy) and theoretical (B3LYP/6-31G**/LANL2DZ) methods. PTB-1 exhibited a highly selective naked-eye detectable color change from colorless to dark brown and UV-Vis spectral changes for the detection of Ag+ with a detection limit of 3.67 µM in aqueous medium. The detection of Ag+ ions was achieved by test paper strip and supported silica methods. In contrast, PTB-1 exhibited a 23-fold enhanced emission at 420 nm in the presence of Hg2+ ions with a nano-molar detection limit of 0.69 nM. Finally, the sensor PTB-1 was applied successfully for the intracellular detection of Hg2+ ions in a HepG2 liver cell line, which was monitored by use of confocal imaging techniques

In Referense to the Disruption of Verbal Material Consolidation during Medical Sleep

We discuss the problem of the influence of the intravenous anesthetic “Propofol” on the process of human memory consolidation during surgery. This study is relevant because of two co-existing factors. The first is the wide use of propofol during surgical interventions in order to obtain a sedative effect. The second is presence of controversy data about the amnestic effects of the drug on the consolidation of human memory. So, we need to investigate this topic to ensure the safety of propofol medical usage. We used verbal stimuli — 40 words from the Russian language with non-repeating first three letters. Two types of reproduction indicators were compared between three groups — experimental, control and reference. There was no difference found between subjects who were put to sleep and those who were not put to sleep with an anesthetic during surgery. At the same time, the results of reproduction of the memorized material significantly differ from random ones in both groups.В работе обсуждается проблема влияния внутривенного анестетика «Пропофол» на процесс консолидации памяти человека во время хирургической операции. Актуальность исследования обусловлена широтой применения пропофола во время операционных вмешательств с целью получения седативного эффекта при наличии противоречивых данных о наличии амнезогенного влияния препарата на консолидацию памяти человека. Использовались вербальные стимулы — 40 слов из русского языка с неповторяющимися тремя первыми буквами. Два типа показателей воспроизведения сравнивались между тремя группами — экспериментальной, контрольной и референсной. Показано отсутствие различий между испытуемыми, введенными и не введенными в состояние сна с помощью анестетика во время хирургического вмешательства. При этом результаты воспроизведения запомненного материала значимо отличаются от случайных в обеих группах.Исследование выполнено при поддержке гранта РФФИ № 19-29-07069

Genomic analysis reveals hidden biodiversity within colugos, the sister group to primates

Colugos are among the most poorly studied mammals despite their centrality to resolving supraordinal primate relationships. Two described species of these gliding mammals are the sole living members of the order Dermoptera, distributed throughout Southeast Asia. We generated a draft genome sequence for a Sunda colugo and a Philippine colugo reference alignment, and used these to identify colugo-specific genetic changes that were enriched in sensory and musculoskeletal-related genes that likely underlie their nocturnal and gliding adaptations. Phylogenomic analysis and catalogs of rare genomic changes overwhelmingly support the contested hypothesis that colugos are the sister group to primates (Primatomorpha), to the exclusion of treeshrews. We captured ~140 kb of orthologous sequence data from colugo museum specimens sampled across their range and identified large genetic differences between many geographically isolated populations that may result in a >300% increase in the number of recognized colugo species. Our results identify conservation units to mitigate future losses of this enigmatic mammalian order.Victor C. Mason, Gang Li Patrick Minx, Jürgen Schmitz, Gennady Churakov, Liliya Doronina, Amanda D. Melin ... et al

Coalescent-based genome analyses resolve the early branches of the euarchontoglires

Despite numerous large-scale phylogenomic studies, certain parts of the mammalian tree are extraordinarily difficult to resolve. We used the coding regions from 19 completely sequenced genomes to study the relationships within the super-clade Euarchontoglires (Primates, Rodentia, Lagomorpha, Dermoptera and Scandentia) because the placement of Scandentia within this clade is controversial. The difficulty in resolving this issue is due to the short time spans between the early divergences of Euarchontoglires, which may cause incongruent gene trees. The conflict in the data can be depicted by network analyses and the contentious relationships are best reconstructed by coalescent-based analyses. This method is expected to be superior to analyses of concatenated data in reconstructing a species tree from numerous gene trees. The total concatenated dataset used to study the relationships in this group comprises 5,875 protein-coding genes (9,799,170 nucleotides) from all orders except Dermoptera (flying lemurs). Reconstruction of the species tree from 1,006 gene trees using coalescent models placed Scandentia as sister group to the primates, which is in agreement with maximum likelihood analyses of concatenated nucleotide sequence data. Additionally, both analytical approaches favoured the Tarsier to be sister taxon to Anthropoidea, thus belonging to the Haplorrhine clade. When divergence times are short such as in radiations over periods of a few million years, even genome scale analyses struggle to resolve phylogenetic relationships. On these short branches processes such as incomplete lineage sorting and possibly hybridization occur and make it preferable to base phylogenomic analyses on coalescent methods

Status on the Michigan‐MIT ultra‐cold polarized hydrogen jet target

Progress on the Mark‐II ultra‐cold polarized atomic hydrogen gas Jet target for the experiments NEPTUN‐A and NEPTUN at UNK is presented. We describe the performance and the present status of different components of the jet.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87525/2/698_1.pd

Tracking Marsupial Evolution Using Archaic Genomic Retroposon Insertions

Genome-wide comparisons of shared retroposon insertion patterns resolve the phylogeny of marsupials, clearly distinguishing South American and Australian species and lending support to Didelphimorphia as the basal split

Семенная продуктивность гибридов рапса

The authors cited the results of studying the seed productivity of rape hybrids of German selection in the soil and climatic conditions of the Krasnoyarsk forest-steppe. The studies were conducted at the experimental plot of the Borsky educational and experimental-production complex of the Krasnoyarsk State Agrarian University (in 2018-2019). The weather conditions of the observation period differed from multi-year data. In 2018, acutely dry conditions were recorded against elevated temperatures from May to August. In 2019, the authors observed a highly uneven rainfall distribution during the growing season. Lack of moisture was noted in May and July 2019; temperatures exceeded the climatic norm all season. A comparative evaluation of the following F1 rapeseed hybrids is presented: Salsa KL, Cultus KL, Currie KL and Lumen. The results of the two-year research showed that the best preservation of plants for harvesting was observed for hybrid Lumen 93.2%, the lowest indicator for F1 Salsa KL was 78.1% of plants preserved. The ability to produce fruit is higher in the Salsa CL hybrid, with an average of 202 pods per plant over two years of observation. The other hybrids had fewer generative pods, ranging from 139 pods in the Currie KL hybrid to 149 in the Lumen hybrid. The highest fruit number was observed for the Currie CL hybrid (31-32 seeds per pod) in each year of the study (the threshold value for spring rapeseed is 40 seeds). Less than in other hybrids, the Lumen hybrid had 22-24 origins in a pod. The authors revealed that the number of seeds in the pod is influenced more by the combination’s genotype than by the pollination period’s weather conditions. The weight of 1000 seeds in spring rape, depending on the hybrid’s biological characteristics and the growing season’s weather conditions, can be 3-5 grams. The complete grains were formed in hybrid Lumen on average for two years of observation weight of 1000 grains was 3.9 g, the smallest seeds in hybrid Kultus KL 3.2 g. All the studied hybrids of spring rape are highly productive. F1 Currie KL was the most effective in oilseed yield, averaging 7.22 t/ha over the study period.Приведены результаты изучения гибридов рапса немецкой селекции на его семенную продуктивность в почвенно-климатических условиях Красноярской лесостепи. Исследования проводились на опытном участке учебно-опытно-производственного комплекса «Борский» Красноярского ГАУ (2018–2019 гг.). Погодные условия периода наблюдений отличались от многолетних данных: в 2018 г. с мая по август отмечены острозасушливые условия на фоне повышенных температур; в 2019 г. – крайне неравномерное распределение осадков вегетационного периода, в мае и июле – недостаток увлажнения, температура весь сезон превышала климатическую норму. Представлена сравнительная оценка следующих гибридов F1 рапса: Сальса КЛ, Культус КЛ, Кюрри КЛ и Люмэн. По результатам двухлетних исследований выявлено, что лучшая сохранность растений к уборке отмечена у гибрида Люмэн – 93,2%, самый низкий показатель у F1 Сальса КЛ – сохранилось 78,1% растений. Способность к плодообразованию выше у гибрида Сальса КЛ, за 2 года наблюдений в среднем на каждом растении получено по 202 стручка. У остальных гибридов генеративных образований несколько меньше: от 139 стручков у гибрида Кюрри КЛ до 149 у гибрида Люмэн. Наибольшая озерненность плодов отмечена у гибрида Кюрри КЛ – по 31–32 шт. семян в стручке по годам исследований (пороговое значение для ярового рапса – 40 шт.). Меньше, чем у других гибридов, получено семян у гибрида Люмэн – в стручке насчитывалось по 22–24 шт. Выявлено, что на количество семян в стручке в большей степени влияет генотип гибрида, чем погодные условия периода опыления. Масса 1000 семян у ярового рапса в зависимости от биологических особенностей гибрида и погодных условий вегетационного периода может быть в пределах 3–5 г. Наиболее полновесные зерна сформировались у гибрида Люмэн – в среднем за 2 года наблюдений масса 1000 зерен составила 3,9 г, самые мелкие семена у гибрида Культус КЛ – 3,2 г. Все изучаемые гибриды ярового рапса высокопродуктивны. По урожайности маслосемян выделен F1 Кюрри КЛ – 7,22 т/га в среднем за период исследований