Sentinel Lymph Node Biopsy in Pure DCIS: Is It Necessary?

Introduction. Sentinel lymph node biopsy (SLNB) in patients with pure ductal carcinoma in situ (DCIS) has been a matter of debate due to very low rate of axillary metastases. We therefore aimed to identify factors in a single institutional series to select patients who may benefit from SLNB. Material and Methods. Patients, diagnosed with pure DCIS (n = 63) between July 2000 and March 2011, were reviewed. All the sentinel lymph nodes were examined by serial sectioning (50 μm) of the entire lymph node and H&E staining, and by cytokeratin immunostaining in suspicious cases. Results. Median age was 51 (range, 30–79). Of 63 patients, 40 cases (63.5%) with pure DCIS underwent SLN, and 2 of them had a positive SLN (5%). In both 2 cases with SLN metastases, only one sentinel lymph node was involved with tumor cells. Patients who underwent SLNB were more likely to have a tumor size >30 mm or DCIS with intermediate and high nuclear grade or a mastectomy in univariate and multivariate analyses. Conclusion. In our series, we found a slightly higher rate of SLNB positivity in patients with pure DCIS than the large series reported elsewhere. This may either be due to the meticulous examination of SLNs by serial sectioning technique or due to our patient selection criteria or both

Recognising Desire: A psychosocial approach to understanding education policy implementation and effect

It is argued that in order to understand the ways in which teachers experience their work - including the idiosyncratic ways in which they respond to and implement mandated education policy - it is necessary to take account both of sociological and of psychological issues. The paper draws on original research with practising and beginning teachers, and on theories of social and psychic induction, to illustrate the potential benefits of this bipartisan approach for both teachers and researchers. Recognising the significance of (but somewhat arbitrary distinction between) structure and agency in teachers’ practical and ideological positionings, it is suggested that teachers’ responses to local and central policy changes are governed by a mix of pragmatism, social determinism and often hidden desires. It is the often underacknowledged strength of desire that may tip teachers into accepting and implementing policies with which they are not ideologically comfortable

Employability and higher education: contextualising female students' workplace experiences to enhance understanding of employability development

Current political and economic discourses position employability as a responsibility of higher education, which deploys mechanisms such as supervised work experience (SWE) to embed employability skills development into the undergraduate curriculum. However, workplaces are socially constructed complex arenas of embodied knowledge that are gendered. Understanding the usefulness of SWE therefore requires consideration of the contextualised experiences of it, within these complex environments. This study considers higher education's use of SWE as a mechanism of employability skills development through exploration of female students' experiences of accounting SWE, and its subsequent shaping of their views of employment. Findings suggest that women experience numerous, indirect gender-based inequalities within their accounting SWE about which higher education is silent, perpetuating the framing of employability as a set of individual skills and abilities. This may limit the potential of SWE to provide equality of employability development. The study concludes by briefly considering how insights provided by this research could better inform higher education's engagement with SWE within the employability discourse, and contribute to equality of employability development opportunity

Correlation Comparisons of Early and Aged Quality Traits of Pork Aged Either as Intact Loins or Case-Ready Chops

Approximately half of retail pork chops in the U.S. arrive at the store in case-ready packages. The other half arrives as intact-loins and are sliced when needed. Cutting chops from loins may increase moisture loss leading to lighter colored and less juicy meat. Therefore, it is possible that correlations between loin quality traits observed early postmortem (PM) and aged quality traits would differ between intact-loin aged (ILA) chops and case-ready aged (CRA) chops. Loins (288 total) were selected to fill a matrix that varied in visual color and marbling. Loins were assigned to 1 of 2 packaging treatments (n = 144): ILA or CRA. Loins assigned as ILA remained vacuum-packaged at 4°C until 12 d PM, sliced and chop surface was evaluated. Loins assigned to CRA were sliced into 28-mm thick chops at 2 d PM, packaged in individual Styrofoam trays overwrapped in polyvinyl-chloride (PVC) film, and gas flushed in bulk packages. Quality parameters of packaging treatments at early and aged time points were compared as a randomized complete block design. Pearson correlation coefficients between early and aged quality traits for packaging treatments were transformed using Fisher’s r to z transformation for independent correlation comparisons of packaging treatments. Chops from ILA were darker and redder at 12 d PM than CRA chops (P < 0.0001). Lightness and redness values on ventral surface for ILA loins (r = 0.52 lightness; r = 0.63 redness) and CRA loins (r = 0.45 lightness; r = 0.61 redness) at 1 d PM were both correlated with aged lightness and redness values on aged chop face at 12 d PM and the correlations did not differ (P ≥ 0.43) for either trait. Overall, aging intact loins in vacuum-packaging improved color after 12 d of aging compared with aging chops in case-ready packaging. Despite the differences between aging methods, the correlations between early and aged loin quality didn’t differ

Population policies and education: exploring the contradictions of neo-liberal globalisation

The world is increasingly characterised by profound income, health and social inequalities (Appadurai, 2000). In recent decades development initiatives aimed at reducing these inequalities have been situated in a context of increasing globalisation with a dominant neo-liberal economic orthodoxy. This paper argues that neo-liberal globalisation contains inherent contradictions regarding choice and uniformity. This is illustrated in this paper through an exploration of the impact of neo-liberal globalisation on population policies and programmes. The dominant neo-liberal economic ideology that has influenced development over the last few decades has often led to alternative global visions being overlooked. Many current population and development debates are characterised by polarised arguments with strongly opposing aims and views. This raises the challenge of finding alternatives situated in more middle ground that both identify and promote the socially positive elements of neo-liberalism and state intervention, but also to limit their worst excesses within the population field and more broadly. This paper concludes with a discussion outling the positive nature of middle ground and other possible alternatives

Mathematical stories: Why do more boys than girls choose to study mathematics at AS-level in England?

Copyright @ 2005 Taylor & FrancisIn this paper I address the question: How is it that people come to choose mathematics and in what ways is this process gendered? I draw on the findings of a qualitative research study involving interviews with 43 young people all studying mathematics in post-compulsory education in England. Working within a post-structuralist framework, I argue that gender is a project and one that is achieved in interaction with others. Through a detailed reading of Toni and Claudia’s stories I explore the tensions for young women who are engaging in mathematics, something that is discursively inscribed as masculine, while (understandably) being invested in producing themselves as female. I conclude by arguing that seeing ‘doing mathematics’ as ‘doing masculinity’ is a productive way of understanding why mathematics is so male dominated and by looking at the implications of this understanding for gender and mathematics reform work.This work is funded by the ESR

The discursive construction of childhood and youth in AIDS interventions in Lesotho's education sector: Beyond global-local dichotomies

This is the post-print version of this article. The definitive, peer-reviewed and edited version of this article is published in Environment and Planning D,Society and Space 28(5) 791 – 810, 2010, available from the link below. Copyright @ 2010 Pion.In southern Africa interventions to halt the spread of AIDS and address its social impacts are commonly targeted at young people, in many cases through the education sector. In Lesotho, education-sector responses to AIDS are the product of negotiation between a range of ‘local’ and ‘global’ actors. Although many interventions are put forward as government policy and implemented by teachers in schools, funding is often provided by bilateral and multilateral donors, and the international ‘AIDS industry’—in the form of UN agencies and international NGOs—sets agendas and makes prescriptions. This paper analyses interviews conducted with policy makers and practitioners in Lesotho and a variety of documents, critically examining the discourses of childhood and youth that are mobilised in producing changes in education policy and practice to address AIDS. Focusing on bursary schemes, life-skills education, and rights-based approaches, the paper concludes that, although dominant ‘global’ discourses are readily identified, they are not simply imported wholesale from the West, but rather are transformed through the organisations and personnel involved in designing and implementing interventions. Nonetheless, the connections through which these discourses are made, and children are subjectified, are central to the power dynamics of neoliberal globalisation. Although the representations of childhood and youth produced through the interventions are hybrid products of local and global discourses, the power relations underlying them are such that they, often unintentionally, serve a neoliberal agenda by depicting young people as individuals in need of saving, of developing personal autonomy, or of exercising individual rights.RGS-IB

A queer politics of emotion: reimagining sexualities and schooling

peer-reviewedThis paper draws together Hochschild’s (1979; 1983) concepts of emotional labour and feeling rules with Ahmed’s affective economies (2004a, 2004b; 2008; 2010) and queer phenomenology (2006a, 2006b) as a way to address wider questions about sexuality and schooling. It highlights the value of the everyday politics of emotion for elucidating and clarifying the specificities, pertinence and complementarities of Hochschild’s and Ahmed’s work for reimagining the relationship between sexualities and schooling. The combination of their approaches allows for a focus on the individual, bodily management of emotions while demonstrating the connectedness of bodies and spaces. It enables disruption of ‘inclusive’ and ‘progressive’ educational approaches that leave heterosexuality uninterrupted and provides insight into how power works in and across the bodies, discourses, practices, relations and spaces of schools to maintain a collective orientation towards heterosexuality. It also counters linear narratives of progressive change, elucidating how change is a hopeful but messy process of simultaneous constraint, transgression and transformation. Key moments from a three-year study with LGBT-Q teachers entering into civil partnerships (CP) in Ireland serve as exploratory examples of the theoretical ideas put forward in this paper.ACCEPTEDpeer-reviewe

Evaluation of Muscle Fiber Characteristics Based on Muscle Fiber Volume in Porcine Longissimus Muscle in Relation to Pork Quality

In livestock science and meat science, muscle fiber characteristics have been evaluated based on a cross-sectional area (CSA) of muscle fiber. However, muscle fiber is not planar but cylindrical. Thus, muscle fiber volume and volume-based characteristics were evaluated in this study. In addition, their relationships to pork loin quality was assessed and compared with that of CSA-based muscle fiber characteristics. Muscle fiber type IIB was underestimated by CSA-based evaluations with 1.6 times in fiber size and 2.6 times in relative composition. The pennation angle, which ranged from 48.00° to 83.33°, determined the real CSA and total number of fibers (TNF) on the surface of a loin chop. Significant (P < 0.05) correlation coefficients were found: fiber volume (r = –0.37) and volume % (r = –0.37) of type IIX with loin length; volume % of type IIX with CIE L* (r = 0.40); volume % of types IIX (r = 0.39) and IIB (r = –0.39) with Warner-Bratzler shear force. Although those correlations to loin quality differed from those of CSA-based characteristics, the Z-scores did not show any significance between the 2 correlation coefficients, except for TNF. Therefore, the conventional methodology for muscle fiber characteristics can be used for evaluating the relationship to pork quality; however, the new methodology is more useful in estimating the characteristics of muscle fiber, which is elongated and cylindrical and to correct the underestimated fiber size and composition of type IIB