Risk of intracranial haemorrhage and ischaemic stroke after convexity subarachnoid haemorrhage in cerebral amyloid angiopathy: international individual patient data pooled analysis

OBJECTIVE: To investigate the frequency, time-course and predictors of intracerebral haemorrhage (ICH), recurrent convexity subarachnoid haemorrhage (cSAH), and ischemic stroke after cSAH associated with cerebral amyloid angiopathy (CAA). METHODS: We performed a systematic review and international individual patient-data pooled analysis in patients with cSAH associated with probable or possible CAA diagnosed on baseline MRI using the modified Boston criteria. We used Cox proportional hazards models with a frailty term to account for between-cohort differences. RESULTS: We included 190 patients (mean age 74.5 years; 45.3% female) from 13 centers with 385 patient-years of follow-up (median 1.4 years). The risks of each outcome (per patient-year) were: ICH 13.2% (95% CI 9.9-17.4); recurrent cSAH 11.1% (95% CI 7.9-15.2); combined ICH, cSAH, or both 21.4% (95% CI 16.7-26.9), ischemic stroke 5.1% (95% CI 3.1-8) and death 8.3% (95% CI 5.6-11.8). In multivariable models, there is evidence that patients with probable CAA (compared to possible CAA) had a higher risk of ICH (HR 8.45, 95% CI 1.13-75.5, p = 0.02) and cSAH (HR 3.66, 95% CI 0.84-15.9, p = 0.08) but not ischemic stroke (HR 0.56, 95% CI 0.17-1.82, p = 0.33) or mortality (HR 0.54, 95% CI 0.16-1.78, p = 0.31). CONCLUSIONS: Patients with cSAH associated with probable or possible CAA have high risk of future ICH and recurrent cSAH. Convexity SAH associated with probable (vs possible) CAA is associated with increased risk of ICH, and cSAH but not ischemic stroke. Our data provide precise risk estimates for key vascular events after cSAH associated with CAA which can inform management decisions

Hot-carrier degradation of CMOS inverters and ring oscillators at 77K

The impact of hot-carrier (HC) stress on CMOS inverters at 77K was examined as a function of temperature. It was found that the degradation in inverter propagation delay was about one order less than that of the device transconductance degradation. Activation energy (EA) of propagation delay exhibited two distinct values from 295K to 77K, with a transition at around 175K for virgin and stressed inverters. The improvement of propagation delay and voltage transfer characteristic (VTC) at 77K compared to 295K was larger for virgin than HC stressed inverters

SemEval-2023 Task 11: Learning With Disagreements (LeWiDi)

The paper contains examples which are offensive in nature. nlp datasets annotated with human judgments are rife with disagreements between the judges. This is especially true for tasks depending on subjective judgments such as sentiment analysis or offensive language detection. Particularly in these latter cases, the nlp community has come to realize that the approach of ‘reconciling’ these different subjective interpretations is inappropriate. Many nlp researchers have therefore concluded that rather than eliminating disagreements from annotated corpora, we should preserve them–indeed, some argue that corpora should aim to preserve all annotator judgments. But this approach to corpus creation for nlp has not yet been widely accepted. The objective of the LeWiDi series of shared tasks is to promote this approach to developing nlp models by providing a unified framework for training and evaluating with such datasets. We report on the second LeWiDi shared task, which differs from the first edition in three crucial respects: (i) it focuses entirely on nlp, instead of both nlp and computer vision tasks in its first edition; (ii) it focuses on subjective tasks, instead of covering different types of disagreements–as training with aggregated labels for subjective nlp tasks is a particularly obvious misrepresentation of the data; and (iii) for the evaluation, we concentrate on soft approaches to evaluation. This second edition of LeWiDi attracted a wide array of participants resulting in 13 shared task submission papers

A Study on continuous and intermittent THAI processes in Brazil's Northeastern Region

Toe-to-Heel Air Injection - THAI is an enhanced oil recovery technique that employs in situ combustion combined with technologies for horizontal well drilling, which is unprecedented in Brazilian oilfields. Motivated by this context, this research is intended to studying the application of the THAI process in a semisynthetic reservoir, with characteristics similar to those found in Brazil's Northeastern region. At the end, it was demonstrated that the intermittent air injection increased the oil recovery, when compared to the continuous injection, what reinforce the need for further research turned to ongoing and future projects in mature oilfields.Fed Univ Para, Engn Coll, BR-68721000 Salinopolis, Para, BrazilUniv Fed Alagoas, Dept Petr Engn, Maceio, Alagoas, BrazilUniv Fed Rio Grande do Norte, Postgrad Program Petr Engn, Natal, RN, BrazilUniv Fed Paraiba, Dept Comp Sci, Joao Pessoa, Paraiba, BrazilUniv Fed Sao Paulo, Dept Marine Sci, Sao Paulo, BrazilUniv Fed Sao Paulo, Dept Marine Sci, Sao Paulo, BrazilWeb of Scienc