9 research outputs found
Żywienie chorych na stwardnienie rozsiane — przegląd piśmiennictwa
Stwardnienie rozsiane (SM, sclerosis multiplex) jest przewlekłą chorobą autoimmunologiczną ośrodkowego układu nerwowego. Jak wskazują liczne badania, istnieje wiele powiązanych ze sobą czynników genetycznych i środowiskowych sprzyjających powstawaniu tej choroby. Obecnie poszukuje się także związku między dietą a przebiegiem chorób przewlekłych, w tym SM. Również rodzaj spożywanych substancji odżywczych uznaje się za jeden z czynników, który może modyfikować naturalny przebieg SM. W wielu badaniach dowiedziono, że prawidłowe żywienie w SM może znacząco wpływać na procesy istotne dla rozwoju choroby, jak również na występowanie dolegliwości jej towarzyszących. Także zaostrzenie niektórych objawów SM jest wiązane z określonymi składnikami diety. Choć ich wpływu ostatecznie nie potwierdzono, to jednak uważa się, że wdrożenie właściwej terapii żywieniowej u chorych na SM, zapobiegając niedoborom substancji odżywczych, wpływa na ogólną poprawę ich stanu zdrowia, łagodzenie objawów oraz poprawę efektywności podstawowego leczenia. Rodzaj diety powinien być uzależniony od stopnia zaawansowania choroby, występowania objawów towarzyszących oraz stosowanego leczenia farmakologicznego. Konieczne jest także dostosowanie sposobu żywienia do indywidualnych potrzeb pacjenta, z uwzględnieniem jego płci, wieku, stopnia aktywności fizycznej oraz ewentualnych chorób współistniejących. Wyniki badań dotyczących wpływu wybranych składników żywności na SM nie są jednoznaczne, co uzasadnia prowadzenie dalszych, wieloośrodkowych, niezależnych badań klinicznych w tym zakresie
Epidemiological Study of Acute Poisoning for Antiepileptic Drugs: A 2-Year Retrospective Study in Cracow, Poland
The aim of this study was designed to examine the rate of occurrence of antiepileptic drug overdose in 2002 and 2012 in Cracow, Poland, and analyze the demographics and clinical features of the patients Antiepileptic drugs (AEDs) intoxication. A retrospective study included all the patients admitted in to the Toxicology Units in Cracow for AED intoxications in 2002 and in 2012. Patients were identified of discharge diagnoses (ICD-10). AED intoxication were 5.40% of the total admissions. Mean age of the patients was 35.88 ± 12.54 years. The female-to-male ratio was 1:1.7. The most frequent AED was carbamazepine (n = 140), followed by valproate (n = 31). The most frequent motivation was intentional intoxication (n = 166, 94.86%). Ethanol was coingested by 51 patients (29.14%). Most of the patients ingested other drugs (32%). Antiepileptic drugs intoxication accounted for only of 7.13% of all cases admitted to the abovementioned toxicology units in 2002 and 2012 in Cracow. Our studies show that most of the AED poisoning cases in those years were caused by drugs belonging to the old generation antiepileptic drugs, including carbamazepine and valproic acid. The majority of the intoxication cases was related to suicidal poisoning and commonest identified reason of self-intoxication were issues with self including attention-seeking behavior
Epidemiology and Risk Factors for Suicide Among Adult Patients with Epilepsy
Suicides constitute a serious public health issue worldwide. The number of suicide victims has been increasing over the years. Susceptibility to suicidal behaviour depends on the interaction of a number of factors. The reasons for taking a decision on committing suicide may objectively seem prosaic, and yet, according to the victim, cannot be resolved in any other way. Very often, it is the disease which is a risk factor for suicide. Suicidal thoughts, suicidal behaviours and suicide attempts as well as committed suicides occur far more frequently in epileptic patients than in the general population. There are many reasons for suicides committed by patients suffering from epilepsy. This paper presents basic data on epidemiology and risk factors of suicide attempts among patients with epilepsy. Risk factors in this group of patients include, inter alia, prior suicide attempts, co-morbidity of epilepsy with depression and other mental disorders, early onset (before 18 years of age), type and frequency of epileptic seizures and the use of anti-epileptic drugs, particularly in polytherapy
Sexual and Psychoemotional Disorders in Male Patients Treated for Prostate Carcinoma
The prostate carcinoma affect the quality of life of most male patients, including in particular their sexual and emotional life. The aim of study was to assess sexual and psychoemotional disorders in male patients diagnosed with prostate carcinoma and receiving cancer treatment. The study’s patients were recruited at the Oncological Hospital in Wieliszew, Poland, between September 2016 and December 2017. The study was performed in 166 male patients diagnosed with prostate cancer. Two standardized questionnaires were used in the study, EORTC QLQ-C30 and QLQ-PR25, for patients with prostate cancer, developed by the European Quality of Life Group. The type and stage of cancer treatments were a significant contributor to feeling tense, worried, depressed, and irritable among the study patients. The stage of treatment, however, caused a negative effect on these parameters. Pretreatment patients declared high or very high satisfaction with their sexual life, while posttreatment patients and those on cancer treatment indicated low sexual satisfaction. However, a feeling of embarrassment during intimate contact as well as erectile disorders correlated both with the type and stage of cancer treatment. Our results show that affected male patients should be offered continuous psychological care, especially those waiting for treatment and those on treatment
Wiedza kursantów ośrodków szkolenia kierowców odnośnie użycia automatycznego defibrylatora zewnętrznego (AED) w trakcie akcji ratunkowej = Students knowledge of driver training center on the use an Automated External Defibrillator (AED) during rescue
Staniszewska Anna, Korczak Anna, Juszczyk Grzegorz, Duda-Zalewska Aneta, Olejniczak Dominik, Dąbrowska-Bender Marta, Bujalska-Zadrożny Magdalena. Wiedza kursantów ośrodków szkolenia kierowców odnośnie użycia automatycznego defibrylatora zewnętrznego (AED) w trakcie akcji ratunkowej = Students knowledge of driver training center on the use an Automated External Defibrillator (AED) during rescue. Journal of Education, Health and Sport. 2015;5(5):67-75. ISSN 2391-8306. DOI: 10.5281/zenodo.17443http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%285%29%3A67-75https://pbn.nauka.gov.pl/works/559145http://dx.doi.org/10.5281/zenodo.17443Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive Deklaracja.Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie.Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).© The Author (s) 2015;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 15.02.2015. Revised 27.04.2015. Accepted: 08.05.2015. Wiedza kursantów ośrodków szkolenia kierowców odnośnie użycia automatycznego defibrylatora zewnętrznego (AED) w trakcie akcji ratunkowejStudents knowledge of driver training center on the use an Automated External Defibrillator (AED) during rescue Anna Staniszewska1*, Anna Korczak2, Grzegorz Juszczyk3, Aneta Duda-Zalewska3, Dominik Olejniczak3, Marta Dąbrowska-Bender3, Magdalena Bujalska-Zadrożny4 1 Katedra i Zakład Farmakologii Doświadczalnej i Klinicznej WUM2 SPZOZ Warszawa Wawer3 Zakład Zdrowia Publicznego WUM4 Zakład Farmakodynamiki WUM *autor do korespondencji: dr n. med. Anna StaniszewskaKatedra i Zakład Farmakologii Doświadczalnej i Klinicznej WUMBanacha 1b, 02-097 Warszawa, tel: (22) 116-61-60, e-mail: [email protected] StreszczenieWstęp: Resuscytacja krążeniowo-oddechowa połączona z wczesną defibrylacją w ciągu 3-5 minut od utraty przytomności może dać efektywną reanimację w 49-75% przypadków, zaś każda minuta opóźnienia defibrylacji zmniejsza prawdopodobieństwo przeżycia poszkodowanego o 10-12%.Cel pracy: Praca miała na celu określenie stanu wiedzy przyszłych kierowców, jaką posiadają na temat automatycznych defibrylatorów zewnętrznych oraz ich użycia w trakcie akcji ratunkowej.Materiał i metoda: Badaniem objęto 200 osób, które wypełniły autorską ankietę na temat automatycznych defibrylatorów zewnętrznych. Badanie przeprowadzono na przełomie 2013 i 2014 roku. W badaniu wykorzystano metodę sondażu diagnostycznego, opartą na technice ankietowej z użyciem kwestionariusza ankiety stworzonej na potrzeby pracy. Do analizy j wyników posłużono się metodą statystyki opisowej.Wyniki i Wnioski: Na podstawie analizy odpowiedzi badanych na pytania ankiety stwierdzono, że wiedza kursantów na temat automatycznego defibrylatora zewnętrznego jest niedostateczna, zarówno pod względem znajomości działania AED, jak i jego lokalizacji. Wyniki przeprowadzonego badania wskazują na konieczność przygotowania i wdrożenia programu edukacyjnego na temat automatycznego defibrylatora zewnętrznego. AbstractIntroduction: Resuscitation cardiopulmonary combined with early defibrillation within 3-5 minutes of unconsciousness can give effective resuscitation cardio-respiratory in 49-75% of cases and each minute of delay defibrillation reduces the probability of survival of the victim by 10-12%.Aim of the study. Evaluation of knowledge about Automated External Defibrillator among the driver training centers students.Material and methods. A group of 200 person was enrolled in order to evaluate the knowledge about Automated External Defibrillator by the special designed questionnaire.in late 2013 and 2014.The study used the method of diagnostic survey, questionnaire based on the technique of using a questionnaire survey of his own design. For the comparative analysis results are used by descriptive statistics.Results and conclusions. Results and conclusions. The knowledge about AED, among driver training centers students is inadequate. The results pointed at necessity of preparation and putting AED education program. Słowa kluczowe: wiedza, kursanci ośrodków szkolenia kierowców, automatyczny defibrylator zewnętrzny.Key words: knowledge, driver training centers students, Automated External Defibrillator
Assessment of Dysphagia as a Risk Factor of Chronic Cough
Background: The aim of the study was to determine the prevalence of dysphagia in patients with chronic cough and its relationship with the long-term persistence of these symptoms. Methods: Thirty consecutive patients. All patients underwent physical examination, ENT assessment, videolaryngoscopy, functional phoniatric assessment at rest and speech, Water-Swallow Test, and Fiberoptic Endoscopic Evaluation of Swallowing disorders with Reflux Finding Score. Reflux Symptom Index questionnaire was performed. The study was approved by the local Ethics Committee Review Board (KB/39/A/2016). Results: The results of the RFS and the RSI questionnaire showed the risk of reflux in participating patients. The patients presented episodes of spillage, double swallows, penetration, aspiration and residue of food at the hypopharynx. The results of functional assessment correlated with the Water-Swallow Test. The correlation between Fiberoptic Endoscopic Evaluation of Swallowing disorders and Water-Swallow Test results was found for aspiration risk, spillage, and retention of saliva. Conclusion: The results of the study showed prevalence of dysphagia in most patients with chronic chough. It seems that phoniatric assessment in those cases should be expanded and the following tests should be performed: assessment of the laryngeal elevation, Water-Swallow Test, and Fiberoptic Endoscopic Evaluation of Swallowing disorders
Health behaviors and health locus of control in patients with epilepsy
Objective: The aim of the study was to show the relation between health behavior and preferred health locus of control in epileptic patients.
Material and methods: One hundred and ninety six participants gave their answers to the Polish version of the Multidimensional Health Locus of Control questionnaire version B and Health Behavior Inventory.
Results: Among all dimensions of health locus of control, the respondents obtained the highest scores in the dimension of internal control (26.0±8.2), and the lowest ones in the dimension of external control (18.0±5.5). The average score for health behaviors was (88.0±11.0). In the category of prophylactic behaviors the highest scores were (23.0±3.6). The category of health practices received the lowest number of points (21.0±3.5). The internal dimension of health control showed a strong significant correlation with the following categories: health behaviors (P=0.00), proper nutrition habits (P=0.00), and positive psychological attitude (P=0.002). The external dimension of health control showed a low significant correlation with health behaviors and prophylactic behaviors (P=0.05). The chance dimension of health control did not show any significant correlations with health behaviors and their categories (P>0.05 in all cases). Conclusion: Our results demonstrate that the participants believed to have more control over their health than other people or chance did. Sociodemographic and clinical factors did not influence health locus of control in patients with epilepsy
SAFETY OF OMBITASVIR/PARITAPREVIR/RITONAVIR+DASABUVIR IN CHRONIC HEPATITIS C PATIENTS WITH HCV GENOTYPE 1 INFECTION
Introduction The assessment of the safety profile of ombitasvir/paritaprevir/ritonavir+dasabuvir in adult chronic hepatitis C patients with confirmed HCV genotype 1 presence. Material and method Evaluation of clinical safety based on the results of primary studies found in the systematic review. The following literature databases were searched: Medline, Embase, Cochrane Library and others. Results Finally two clinical trial met the inclusion criteria. The study included untreated patients (SAPPHIRE I) or patients after unsuccessful therapy (SAPPHIRE II), with genotype 1 infection. In patients without prior treatment the prevalence of the reported adverse events was in general statistically significantly greater in the group on therapy 3D+RBV compared to the placebo group. No statistically significant differences were observed in relation to the risk of serious adverse events or therapy discontinuance due to adverse events. In patients after unsuccessful therapy the prevalence of the reported adverse events was statistically significantly greater in the group on therapy 3D+RBV compared to the placebo group. During the 3D+RBV itching was statistically significantly more frequently reported in the placebo group. Compared to the other adverse events, no statistically significant differences were observed. Conclusions Interferon-free therapies provide a safe therapeutic option in the population of adult patients with chronic genotype 1 hepatitis C, both those untreated and after unsuccessful two-drug PegIFNα-based therapy, patients with HIV co-infection and patients after liver transplantation
COMPARISON OF PERSONALIZED AND STANDARD PROPHYLAXIS BASED ON OCTOCOG ALFA IN PEDIATRIC PATIENTS WITH HEMOPHILIA A
Comparison of personalized and standard prophylaxis prevention therapies based on octocog alfa in pediatric patients with hemophilia A. Studies on a general population (adults and children) demonstrate a statistically significant advantage of personalized prevention therapy over standard prophylaxis prevention therapy in terms of annual bleeding rate (ABR) and annual joint bleeding rate (AJBR) while studies on a pediatric population included insufficiently large populations, however, their results demonstrate a numerical advantage of personalized approach over standard prevention strategy prophylaxis regimen