Functional signatures in non-small-cell lung cancer: a systematic review and meta-analysis of sex-based differences in transcriptomic studies

While studies have established the existence of differences in the epidemiological and clinical patterns of lung adenocarcinoma between male and female patients, we know relatively little regarding the molecular mechanisms underlying such sex-based differences. In this study, we explore said differences through a meta-analysis of transcriptomic data. We performed a meta-analysis of the functional profiling of nine public datasets that included 1366 samples from Gene Expression Omnibus and The Cancer Genome Atlas databases. Meta-analysis results from data merged, normalized, and corrected for batch effect show an enrichment for Gene Ontology terms and Kyoto Encyclopedia of Genes and Genomes pathways related to the immune response, nucleic acid metabolism, and purinergic signaling. We discovered the overrepresentation of terms associated with the immune response, particularly with the acute inflammatory response, and purinergic signaling in female lung adenocarcinoma patients, which could influence reported clinical differences. Further evaluations of the identified differential biological processes and pathways could lead to the discovery of new biomarkers and therapeutic targets. Our findings also emphasize the relevance of sex-specific analyses in biomedicine, which represents a crucial aspect influencing biological variability in diseaseThis work was supported by Fondo de Investigación Sanitaria (ISCIII PI15-00209), GV/2020/ 186, and ISCIII PT17/0009/0015 FEDE

Information and Communication Technologies (ICT) for training in sheep handling and production

El desarrollo de TIC para el aprendizaje de los alumnos es de suma importancia en la situación actual. Se pretende el desarrollo de material audiovisual para que la adquisición de las competencias en materia de manejo, cría y producción ovina.Depto. de Producción AnimalFac. de VeterinariaFALSEsubmitte

Pinterest: Use of social networks for horse and dog coat study

Depto. de Producción AnimalFac. de VeterinariaFALSEsubmitte

CUIDADO DE UN NÚCLEO DE GALLINAS EN PELIGRO DE EXTINCIÓN POR LOS ESTUDIANTES DEL DIPLOMA FORMATIVO UNIVERSITARIO LICEO-ESPECIALIDAD DE CUIDADO DE ANIMALES (GALLICEO)

Depto. de Producción AnimalDepto. de Farmacología y ToxicologíaDepto. de Investigación y Psicología en EducaciónFac. de EducaciónTRUEinpres

From farm to commercialization: An integration strategy in Food Science and Technology

De la Granja a la Comercialización: Una experiencia de integración. Comunicación presentada en el III Congreso CyTA-Junior. Zaragoza. 20 de junio de 2022Integración de la Granja Docente de Veterinaria en las actividades prácticas del Grado en Ciencia y Tecnología de los Alimentos; creación de una plataforma virtual como herramienta de coordinación de la producción-elaboración y comercialización de productos.Integration of the Veterinary Teaching Farm in the practical activities of the degree in Food Science and Technology; creating a virtual platform as a tool to coordinate the production, manufacture and marketing of food products.Fac. de VeterinariaFALSEsubmitte

Integrate and learn. Building a farm-to-table blockchain

DecanatoFac. de VeterinariaFALSEsubmitte