Detecção de resistência a inseticidas neurotóxicos em populações de Bemísia tabaci biótipo B (Hemiptera: Aleyrodidae) oriundas do Sudeste e Centro-Oeste brasileiro.

Este trabalho teve por objetivo realizar um levantamento dos níveis de resistência de B. tabaci a inseticidas neurotóxicos em lavouras do Sudeste e Centro-Oeste do Brasil.Resumo 070

Dosimetric evaluation in radiation synovectomy

Rheumatoid arthritis can manifest itself through synovitis, of which the knee is the common locale. The treatment using an intra-articular radioisotope injection has been applied in various countries. In this work, the dose of radioactive material absorbed in the joint is evaluated, taking into consideration the dose received in the articular cartilage and adjacencies using a three-dimensional voxel model representing the knee. The radioisotopes studied were Samarium-153 and Dysprosium-165. The results show that the synovial membrane receives 85 to 98% of the normalized dose taken from all voxels representative of the synovium. The following features of 153Sm and of 165Dy - its short physical half-life, the gamma emissions with low energy which allow monitoring the injection trough scintigraphy images, the possibility of binding themselves to macroaggregates that are retained in the joint, the high percentage of the effective dose spread in the synovial membrane - make these suitable radioisotopes for radiation synovectomy.<br>A artrite reumatóide pode se manifestar usualmente pela inflamação da membrana sinovial caracterizada como sinovite, sendo o joelho um substrato comum. O tratamento com a injeção intra-articular de radioisótopo, ou sinovectomia radioisotópica, vem sendo estudado. Neste trabalho será calculada a dose absorvida na sinóvia e nas adjacências através de um modelo tridimensional de voxels. Os radioisótopos estudados foram o Samário-153 e o Disprósio-165. Os resultados obtidos mostraram que uma taxa de dose máxima normalizada variando de 85 a 98% da dose máxima foi atingida em todos os voxels representativos da membrana sinovial. As características nucleares do Samário-153 e do Disprósio-165, associadas à taxa de dose efetiva recebida na articulação, fazem destes radioisótopos uma escolha na sinovectomia radioisotópica

Can morphine interfere in the healing process during chronic stress?

Technological advances, constant pressure, increased qualified demand, and other daily activities present in modern society result in increasingly stressful living conditions for the population. in the short term, the release of stress-related hormones can play a key role in the survival of an organism. However, it is well known that chronic exposure to cortisol can lead to many adverse effects. Several findings show immunological changes in response to chronic exposure to cortisol, in particular in skin integrity, which may interfere with the healing process. Morphine is an immunosuppressive drug, and when it is used chronically, it can lead to an increased incidence of infections and a delay in the healing process. the importance of opiates as analgesics in the medical setting is indisputable. However, there are a limited number of studies in this field. These investigations can provide further understanding of the mechanisms involved in the healing process in morphine-dependent individuals under chronic stress, which is a common condition in modern society. Furthermore, medical prescriptions of opiates are common among terminal patients, who frequently develop decubitus ulcers and bacterial infections. This review is aimed to provide a concise analysis of effects of morphine and stress on the healing process.Associacao Fundo de Incentivo a Pesquisa (AFIP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Federal de São Paulo UNIFESP, Dept Psicobiol, BR-04024002 São Paulo, BrazilUniversidade Federal de São Paulo UNIFESP, Dept Dermatol, BR-04024002 São Paulo, BrazilUniversidade Federal de São Paulo UNIFESP, Dept Psicobiol, BR-04024002 São Paulo, BrazilUniversidade Federal de São Paulo UNIFESP, Dept Dermatol, BR-04024002 São Paulo, BrazilFAPESP: 11/14462FAPESP: 07/55445-6FAPESP: 98/14303-3Web of Scienc