New Technology Tools and Life Cycle Analysis (LCA) Applied to a Sustainable Livestock Production

Agriculture 4.0, a combination of mechanical innovation and information and communication technologies (ICT) using precision farming, omics technologies and advanced waste treatment techniques, can be used to enhance the biological potential of animal and crop productions and reduce livestock gaseous emissions. In addition to animal proteins being excellent nutritional ingredients for the human diet, there is a growing concern regarding the amount of energy spent converting vegetable crops into animal protein and the relevant environmental impacts. Using the value chain analysis derived from the neoclassic production theory extended to industrial processing and the market, the hypothesis to be tested concerns the sustainability and convenience of different protein sources. The methodology implies the use of life cycle analysis (LCA) to evaluate the efficiency of different livestock diet ingredients. The use of feeding products depend upon various factors, including cost reduction, consumer acceptance, incumbent industry response, civil society support, policy consensus, lower depletion of natural resources, improved sustainable agri-food supply chain and LCA. EU policy makers should be aware of these changes in livestock and market chains and act proactively to encourage the use of alternative animal proteins

Transcritical CO2 commercial refrigeration plant with adiabatic gas cooler and subcooling via HVAC: field tests and modelling

Subcooling methods at the exit of the gas cooler in transcritical CO2 commercial refrigeration systems have been studied in the recent years showing that overall remarkable improvements can be obtained. Another strategy that results efficient is the use of evaporative systems at the gas cooler (adiabatic cooling) as it allows to significantly reduce the refrigerant quality at the liquid receiver and to lower the heat rejection pressure. In this work, a fully instrumented CO2 transcritical booster system with parallel compression, in operation in a small size supermarket in northern Italy, made available measured data of its performance when subcooling and/or adiabatic cooling are active. The plant operates in a mild climate, where it suffers operation at transcritical conditions for most of the year. Subcooling in this plant is performed by coupling the refrigeration system with the HVAC system. Taking advantage of experimental measurements, a model in the TRNSYS environment is validated and allows the prediction of the annual plant performance when these strategies are adopted. The adiabatic cooling showed to allow a significant reduction (about 10%) in the energy use, and makes unnecessary the use of a parallel compressor. Subcooling by the HVAC gives rise to a reduced saving (2.9 %) due to the absence of a dedicated mechanical subcooler, however it is almost comparable to parallel compression. These trends are confirmed in two other hot and humid climates

FIELD TESTS, MODEL VALIDATION AND PERFORMANCE OF A CO2 COMMERCIAL REFRIGERATION PLANT INTEGRATED WITH HVAC SYSTEM

A fully instrumented CO2 trans-critical booster system with parallel compression, in operation in a small size supermarket in northern Italy, made available measured data that allowed monitoring its performance. The entire refrigeration system of the supermarket, i.e. the Commercial Refrigerating Unit, the refrigerated display cabinets and cold rooms, have been modelled in TRNSYS with in-house types for all components. The comparison with the field data available from monitoring the plant allowed to thoroughly calibrate the model, spanning the operation conditions of a whole year. The validated model is a reliable and powerful tool, usable to predict the plant performance in several conditions and to evaluate the feasibility and effectiveness of the integration with DHW/HVAC systems. Measurements and simulations show that, at mild climate conditions, it is possible and effective to fully provide HVAC and refrigeration duties with a single all-in-one unit properly designed and operated

Effect of dedicated mechanical subcooler size and gas cooler pressure control on transcritical CO2 booster systems

Dedicated Mechanical Subcooling (DMS) is one of the most investigated and effective strategies applied to increase the performance of CO2 commercial refrigeration systems in transcritical operation. Further performance benefits can be obtained by a reduction of the gas cooler pressure of the main cycle at transcritical conditions. In this work the most important parameters for the design and operation of such a system, i.e. the DMS cooling capacity, the subcooling degree and the gas cooler pressure, are considered and their effect on the annual energy use of the plant is estimated in warm and hot climate conditions by means of a validated model. DMS is also compared to the parallel compression scheme and subcooling performed through a water chiller dedicated to HVAC. DMS results to be the most effective solution among those investigated, and the choice of the best design and operating parameters allows further energy saving and cost reduction

Isolation and full-length genome characterization of Sarscov-2 from covid-19 cases in northern Italy

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The effect of plant extracts kalanchoe daigremontiana and aloe arborescens on the metabolism of human multiple myeloma cells

The effect of plant extracts Kalanchoe daigremontiana, and Aloe arborescens on human multiple myeloma cells' viability was investigated. It was shown that plant extracts of kalanchoe and aloe reduced tumor cells' viability by 13 and 46%, respectively. The combination of plant extracts with doxorubicin showed an additive synergism of action, enhancing the antitumor effect. Treatment of multiple myeloma cells with plant extracts led to a decrease in intracellular reduced glutathione level. The intracellular glutathione level decreased by 25% under the action of kalanchoe extract and by 63% under the action of aloe extract. Extracts from kalanchoe and aloe decreased mitochondrial membrane potential by 19 and 53%, respectively. The results of the study showed that kalanchoe extract increased ATPase activity, but aloe extract did not affect the level of ATPase activity. The results showed that plant extracts of kalanchoe and aloe affect tumor cells' metabolism and contribute to their death. It was concluded that herbal extracts Kalanchoe daigremontiana and Aloe arborescens have antitumor activity, and aloe extract is more effective than kalanchoe

COVID-19 outbreak in healthcare workers in hospitals in Trieste, North-east Italy

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The burden of severe cases of Influenza disease: The Friuli Venezia Giulia Region experience

IIntroduction. Influenza is a matter of serious concern for clinicians, in both outpatient and in-hospital settings. Worldwide, the 2017-18 epidemic proved to be the most severe since 2003-04. We report a real-world experience regarding the management of patients with influenza admitted to a large teaching hospital in the Friuli Venezia Giulia region during the 2017-2018 influenza season. We also provide a practical guide for the management of hospitalized influenza patients. Methods. A retrospective observational analysis was conducted among all influenza patients requiring admission to our center during the 2017-18 season. Results. Overall, 29 patients were admitted to the University Hospital of Udine during the 2017-18 season with a diagnosis of influenza. B virus was responsible for the majority of cases. More than 65.5% of the subjects presented with a complication. We estimated that 41.4% of the patients admitted were affected by a \u201csevere form\u201d. All these cases required admission to the Intensive Care Unit, with 27.6% and 10.3% needing Orotracheal Intubation and Extracorporeal Membrane Oxygenation, respectively. The fatality rate was 24.1%. Notably, only 9 subjects in our cohort had been vaccinated. Based on the experience acquired during the past season, we propose a practical guide to the management of influenza cases in everyday hospital practice. Conclusion. The cornerstones of the management of all hospitalized influenza patients are the rapid identification and treatment of severe forms. Timely and strict adherence to contact and respiratory precautions are also fundamental to reducing the risk of intra-hospital outbreaks. Despite improvements in antiviral therapies and supportive measures, influenza-related morbidity and mortality remain high. In our opinion, a universal vaccination program is the only safe and effective method of filling the gap

Measles in Italy: Viral strains and crossing borders

In 2017, Italy experienced one of the largest outbreaks of measles in recent years, with 5404 notified cases and 4347 confirmed cases. A further 2029 cases were notified during the first 6 months of 2018, and 1516 of them were laboratory-confirmed. The B3 and D8 genotypes were identified as those responsible for the outbreak. Possible transmission routes can be established by monitoring the circulating measles virus strains in support of the national health authorities to warn people and travellers

Has VZV epidemiology changed in Italy? Results of a seroprevalence study

The aim of the study was to evaluate if and how varicella prevalence has changed in Italy. In particular a seroprevalence study was performed, comparing it to similar surveys conducted in pre-immunization era. During 2013–2014, sera obtained from blood samples taken for diagnostic purposes or routine investigations were collected in collaboration with at least one laboratory/center for each region, following the approval of the Ethics Committee. Data were stratified by sex and age. All samples were processed in a national reference laboratory by an immunoassay with high sensitivity and specificity. Statutory notifications, national hospital discharge database and mortality data related to VZV infection were analyzed as well. A total of 3707 sera were collected and tested. In the studied period both incidence and hospitalization rates decreased and about 5 deaths per year have been registered. The seroprevalence decreased in the first year of life in subjects passively protected by their mother, followed by an increase in the following age classes. The overall antibody prevalence was 84%. The comparison with surveys conducted with the same methodology in 1996–1997 and 2003–2004 showed significant differences in age groups 1–19 y. The study confirms that in Italy VZV infection typically occurs in children. The impact of varicella on Italian population is changing. The comparison between studies performed in different periods shows a significant increase of seropositivity in age class 1–4 years, expression of vaccine interventions already adopted in some regions