120 research outputs found

    Nuclear Attenuation of high energy two-hadron system in the string model

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    Nuclear attenuation of the two-hadron system is considered in the string model. The two-scale model and its improved version with two different choices of constituent formation time and sets of parameters obtained earlier for the single hadron attenuation, are used to describe available experimental data for the zz-dependence of subleading hadron, whereas satisfactory agreement with the experimental data has been observed. A model prediction for ν\nu-dependence of the nuclear attenuation of the two-hadron system is also presented.Comment: 8 page

    CALIBRATION AND APPLICATION OF NUCLEAR TRACK DETECTORS FOR HIGH-TEMPERATURE PLASMA DIAGNOSTICS

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    Abstract The paper reports on features of so-called solid-state nuclear track detectors (SSNTDs), their calibration measurements performed with known ion beams, and their different applications for detailed studies of charged particle emissions from various high-temperatures plasma facilities

    Nuclear Attenuation of Fast Hadrons Produced in Charged-Current Neutrino and Antineutrino Interactions in Neon

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    The production of hadrons in charged-current (anti)neutrino interactions is studied with the bubble chamber BEBC exposed ot the CERN (anti)neutrino wide-band beam. Fast-hadron production in a neon target is found to be attennuated as compared to that in a hydrogen target. This feature is discussed within the theoretical models based on the idea of a hadron formation length. The experimental results favour the `constituent' over the `yo-yo' length concept, and suggest a quark cross-section in the order of 3mb.Comment: 14 pages + 7 figures, ps fil

    Recommendations of the task force on public policy

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    This is the published version, reproduced here with permission from the publisher. This article is also available electronically from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741851/.The Task Force on Public Policy was established by the Association for Behavior Analysis to examine ways to encourage members to contribute to policymaking relevant to the public interest. Members discussed issues pertinent to this activity and summarized their discussion in a formal report.' Recommendations of the Task Force for conducting and disseminating policy research and for training, technical assistance, and other services supportive of behavior-analytic research in the public policy arena are presented here

    Predicting cardiovascular stent complications using self-reporting biosensors for noninvasive detection of disease

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    Self-reporting implantable medical devices are the future of cardiovascular healthcare. Cardiovascular complications such as blocked arteries that lead to the majority of heart attacks and strokes are frequently treated with inert metal stents that reopen affected vessels. Stents frequently re-block after deployment due to a wound response called in-stent restenosis (ISR). Herein, an implantable miniaturized sensor and telemetry system are developed that can detect this process, discern the different cell types associated with ISR, distinguish sub plaque components as demonstrated with ex vivo samples, and differentiate blood from blood clot, all on a silicon substrate making it suitable for integration onto a vascular stent. This work shows that microfabricated sensors can provide clinically relevant information in settings closer to physiological conditions than previous work with cultured cells

    Is there a difference between child self-ratings and parent proxy-ratings of the quality of life of children with a diagnosis of Attention Deficit Hyperactivity Disorder (ADHD)? A systematic review of the literature

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    There are contemporary indicators that parent proxy-ratings and child self-ratings of a child’s quality of life (QoL) are not interchangeable. This review examines dual informant studies to assess parent–child agreement on the QoL of children with attention-deficit/hyperactivity disorder. A systematic search of four major databases (PsycINFO, MEDLINE, EMBASE and Cochrane databases) was completed, and related peer-reviewed journals were hand-searched. Studies which reported quantitative QoL ratings for matched parent and child dyads were screened in accordance with relevant inclusion and exclusion criteria. Key findings were extracted from thirteen relevant studies, which were rated for conformity to the recommendations of an adapted version of the STROBE statement guidelines for observational studies. In the majority of studies reviewed, children rated their QoL more highly than their parents. There was some evidence for greater agreement on the physical health domain than psychosocial domains

    In Vivo, In Vitro, and In Silico Characterization of Peptoids as Antimicrobial Agents

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    Bacterial resistance to conventional antibiotics is a global threat that has spurred the development of antimicrobial peptides (AMPs) and their mimetics as novel anti-infective agents. While the bioavailability of AMPs is often reduced due to protease activity, the non-natural structure of AMP mimetics renders them robust to proteolytic degradation, thus offering a distinct advantage for their clinical application. We explore the therapeutic potential of N-substituted glycines, or peptoids, as AMP mimics using a multi-faceted approach that includes in silico, in vitro, and in vivo techniques. We report a new QSAR model that we developed based on 27 diverse peptoid sequences, which accurately correlates antimicrobial peptoid structure with antimicrobial activity. We have identified a number of peptoids that have potent, broad-spectrum in vitro activity against multi-drug resistant bacterial strains. Lastly, using a murine model of invasive S. aureus infection, we demonstrate that one of the best candidate peptoids at 4 mg/kg significantly reduces with a two-log order the bacterial counts compared with saline-treated controls. Taken together, our results demonstrate the promising therapeutic potential of peptoids as antimicrobial agents

    Technical Design Report for the: PANDA Micro Vertex Detector

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    This document illustrates the technical layout and the expected performance of the Micro Vertex Detector (MVD) of the PANDA experiment. The MVD will detect charged particles as close as possible to the interaction zone. Design criteria and the optimisation process as well as the technical solutions chosen are discussed and the results of this process are subjected to extensive Monte Carlo physics studies. The route towards realisation of the detector is outlined.Comment: 189 pages, 225 figures, 41 table
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