PHI-base: the pathogen-host interactions database.

The pathogen-host interactions database (PHI-base) is available at www.phi-base.org. PHI-base contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions reported in peer reviewed research articles. PHI-base also curates literature describing specific gene alterations that did not affect the disease interaction phenotype, in order to provide complete datasets for comparative purposes. Viruses are not included, due to their extensive coverage in other databases. In this article, we describe the increased data content of PHI-base, plus new database features and further integration with complementary databases. The release of PHI-base version 4.8 (September 2019) contains 3454 manually curated references, and provides information on 6780 genes from 268 pathogens, tested on 210 hosts in 13,801 interactions. Prokaryotic and eukaryotic pathogens are represented in almost equal numbers. Host species consist of approximately 60% plants (split 50:50 between cereal and non-cereal plants), and 40% other species of medical and/or environmental importance. The information available on pathogen effectors has risen by more than a third, and the entries for pathogens that infect crop species of global importance has dramatically increased in this release. We also briefly describe the future direction of the PHI-base project, and some existing problems with the PHI-base curation process

Genetic characterisation of four genes in Arabidopsis required for a non salicylate dependent source of downy mildew resistance

SIGLEAvailable from British Library Document Supply Centre- DSC:DXN056278 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

PHI-base/phipo: 2023-09-07 September 2023 release

PHIPO September 2023 release <p>This release contains the following changes since the previous release (3 August 2023).</p> New terms <ul> <li>normal growth on amphotericin B (PHIPO:0001352) (#421)</li> <li>normal growth on itraconazole (PHIPO:0001351) (#422)</li> <li>resistance to triflumizole (PHIPO:0001342) (#419)</li> <li>sensitive to triflumizole (PHIPO:0001343) (#419)</li> <li>normal growth on triflumizole (PHIPO:0001344) (#419)</li> <li>resistance to bitertanol (PHIPO:0001345) (#419)</li> <li>sensitive to bitertanol (PHIPO:0001346) (#419)</li> <li>normal growth on bitertanol (PHIPO:0001347) (#419)</li> <li>resistance to pyrifenox (PHIPO:0001348) (#419)</li> <li>sensitive to pyrifenox (PHIPO:0001349) (#419)</li> <li>normal growth on pyrifenox (PHIPO:0001350) (#419)</li> <li>normal growth on thiabendazole (PHIPO:0001341) (#418)</li> <li>resistance to nocodazole (PHIPO:0001340) (#417)</li> <li>sensitive to procymidone (PHIPO:0001339) (#415)</li> <li>sensitive to thiram (PHIPO:0001338) (#414)</li> <li>sensitive to fluazinam (PHIPO:0001337) (#413)</li> <li>sensitive to myclobutanil (PHIPO:0001336) (#409)</li> <li>resistance to myclobutanil (PHIPO:0001335) (#409)</li> <li>resistance to fluazinam (PHIPO:0001334) (#413)</li> <li>resistance to thiram (PHIPO:0001333) (#414)</li> <li>resistance to procymidone (PHIPO:0001332) (#415)</li> <li>normal growth on procymidone (PHIPO:0001331) (#415)</li> <li>normal growth on thiram (PHIPO:0001330) (#414)</li> <li>normal growth on fluazinam (PHIPO:0001329) (#413)</li> <li>normal growth on myclobutanil (PHIPO:0001328) (#409)</li> <li>normal growth on iprodione (PHIPO:0001327) (#410)</li> <li>normal growth on prochloraz (PHIPO:0001326) (#411)</li> <li>normal growth on tebuconazole (PHIPO:0001325) (#412)</li> <li>normal growth on pyrimethanil (PHIPO:0001324) (#416)</li> </ul> <p><strong>Full Changelog</strong>: <a href="https://github.com/PHI-base/phipo/compare/v2023-08-03...v2023-09-07">https://github.com/PHI-base/phipo/compare/v2023-08-03...v2023-09-07</a></p&gt

PHI-base/phipo: 2023-07-06 July release

PHIPO July 2023 release <p>This release contains the following changes since the previous release (29 June 2023).</p> New terms <ul> <li>resistance to salt stress (PHIPO:0001304) (#399)</li> <li>resistance to non-ionic osmotic stress (PHIPO:0001305) (#399)</li> <li>sensitive to salt stress (PHIPO:0001306) (#399)</li> <li>sensitive to non-ionic osmotic stress (PHIPO:0001307) (#399)</li> </ul> <p><strong>Full Changelog</strong>: <a href="https://github.com/PHI-base/phipo/compare/v2023-06-29...v2023-07-06">https://github.com/PHI-base/phipo/compare/v2023-06-29...v2023-07-06</a></p&gt

PHI-base/phipo: 2023-08-03 August 2023 release

PHIPO August 2023 release <p>This release contains the following changes since the previous release (6 July 2023).</p> New terms <ul> <li>normal growth on chemical (PHIPO:0001308) (#400)</li> <li>normal growth on benomyl (PHIPO:0001309) (#402)</li> <li>normal growth on carbendazim (PHIPO:0001310) (#403)</li> <li>normal growth on chlorothalonil (PHIPO:0001311) (#405)</li> <li>normal growth on zoxamide (PHIPO:0001312) (#404)</li> <li>resistance to zoxamide (PHIPO:0001313) (#404)</li> <li>sensitive to zoxamide (PHIPO:0001314) (#404)</li> <li>normal growth on cymoxanil (PHIPO:0001315) (#406)</li> <li>resistance to cymoxanil (PHIPO:0001316) (#406)</li> <li>sensitive to cymoxanil (PHIPO:0001317) (#406)</li> <li>normal growth on metalaxyl (PHIPO:0001318) (#407)</li> <li>resistance to metalaxyl (PHIPO:0001319) (#407)</li> <li>sensitive to metalaxyl (PHIPO:0001320) (#407)</li> <li>normal growth on flumorph (PHIPO:0001321) (#408)</li> <li>resistance to flumorph (PHIPO:0001322) (#408)</li> <li>sensitive to flumorph (PHIPO:0001323) (#408)</li> </ul> Moved terms <p>Normal growth terms (e.g. normal growth on voriconazole) are now child terms of 'normal growth on chemical' (PHIPO:0001308). See commit ec5af6f for details.</p> <p><strong>Full Changelog</strong>: <a href="https://github.com/PHI-base/phipo/compare/v2023-07-06...v2023-08-03">https://github.com/PHI-base/phipo/compare/v2023-07-06...v2023-08-03</a></p&gt

PHI-base/phipo: 2023-06-22 June release 2

PHIPO June 2023 release 2 <p>This release contains the following changes since the previous release (19 June 2023).</p> New terms <ul> <li>inhibition of pathogen polygalacturonase by host present (PHIPO:0001294) (#384)</li> <li>inhibition of pathogen polygalacturonase by host decreased (PHIPO:0001295) (#384)</li> <li>resistance to arborcandin C (PHIPO:0001296) (#397)</li> <li>sensitive to arborcandin C (PHIPO:0001297) (#397)</li> <li>normal growth on arborcandin C (PHIPO:0001218) (#397)</li> </ul> <p><strong>Full Changelog</strong>: <a href="https://github.com/PHI-base/phipo/compare/v2023-06-19...v2023-06-22">https://github.com/PHI-base/phipo/compare/v2023-06-19...v2023-06-22</a></p&gt

PHI-base/phipo: 2023-10-11 October 2023 release

PHIPO October 2023 release This release contains the following changes since the previous release (7 September 2023). New terms resistance to prothioconazole (PHIPO:0001353) (#419) sensitive to prothioconazole (PHIPO:0001354) (#419) normal growth on prothioconazole (PHIPO:0001355) (#419) resistance to fluopyram (PHIPO:0001356) (#419) sensitive to fluopyram (PHIPO:0001357) (#419) normal growth on fluopyram (PHIPO:0001358) (#419) resistance to kresoxim-methyl (PHIPO:0001359) (#419) sensitive to kresoxim-methyl (PHIPO:0001360) (#419) normal growth on kresoxim-methyl (PHIPO:0001361) (#419) resistance to isopyrazam (PHIPO:0001362) (#419) sensitive to isopyrazam (PHIPO:0001363) (#419) normal growth on isopyrazam (PHIPO:0001364) (#419) resistance to bixafen (PHIPO:0001365) (#419) sensitive to bixafen (PHIPO:0001366) (#419) normal growth on bixafen (PHIPO:0001367) (#419) normal growth on carboxin (PHIPO:0001368) (#419) increased rate of hyphae formation (PHIPO:0001369) (#423) resistance to pyrimorph (PHIPO:0001370) (#419) sensitive to pyrimorph (PHIPO:0001371) (#419) normal growth on pyrimorph (PHIPO:0001372) (#419) Full Changelog: https://github.com/PHI-base/phipo/compare/v2023-09-07...v2023-10-1