Pathologic use of video games and gotivation. Can the Gaming Motivation Scale (GAMS) predict depression and trait anxiety?

Videogaming is an increasingly prevalent activity among adolescents worldwide. The present study aimed at adapting the Gaming Motivation Scale (GAMS) to the Italian context, assessing its psychometric properties and verifying its sensitivity to predict depression and anxiety levels. From a sample of 1899 participants, a group of 388 adolescents who participated in the survey was divided into two subgroups of Heavy (HG, N = 188) and Light Gamers (LG, N = 200). A sub-sample of N = 172 adolescents also filled-in CESD and STAI to assess, respectively, depression and trait anxiety. Internal consistency and factorial structure of the Italian version of GAMS (GAMS-it) have been evaluated. Moreover, a latent regression structural equation model by predicting the CES-D and STAI scores with the GAMS-it factors has been carried out. GAMS-it has adequate validity and reliability levels, showing a very similar factorial structure to the original version. Therefore, this scale can be used to evaluate gaming motivation, which is useful for gaming motivation screening. Finally, it has been found that lower gaming motivation can be related to high level of depression and anxiety. The present findings provide a coherent picture, supporting the reliability and validity of the GAMS-it, that appears potentially useful in predicting anxiety and depression levels in a population of adolescent

Honeypot-powered Malware Reverse Engineering

Honeypots, i.e. networked computer systems specially designed and crafted to mimic the normal operations of other systems while capturing and storing information about the interactions with the world outside, are a crucial technology into the study of cyber threats and attacks that propagate and occur through networks. Among them, high interaction honeypots are considered the most efficient because the attacker (whether automated or not) perceives realistic interactions with the target machine. In the case of automated attacks, propagated by malwares, currently available honeypots alone are not specialized enough to allow the analysis of their behaviors and effects on the target system. The research presented in this paper shows how high interaction honeypots can be enhanced by powering them with specific features that improve the reverse engineering activities needed to effectively analyze captured malicious entities

Nurses Alumni Association Bulletin, Fall 2014

2014 - 2015 Meeting Dates Calendar 2015 Annual Luncheon & Meeting Notice Officers, Committee Chairs, Satellite and Volunteers President\u27s Message Treasurer\u27s Report Resume of Minutes Alumni Office News Committee Reports Social Relief Trust Fund Satellite-Harrisburg Satellite Area Scholarship Nominating Bulletin By Laws Jefferson Alumni Relations Annual Giving Janet C. Hindson Award Award Criteria Nominees Recipient News About Our Graduates Memories Happy Birthday - To Be 80 or More 50th Anniversary Class List for 1964 Luncheon Reservations Annual Luncheon Comments Luncheon Photos Anniversary Class List for 2015 Annual Luncheon In Memoriam, Names of Deceased Graduates Class News Additional Information, Pins, Transcripts & Address Info Scholarship Fund Application Descendant Nurses\u27 Scholarship Fund Application Certification Reimbursement Application Relief Fund Trust Benefits Application List of Hotels Campus Ma

Antioxidant and Anti-Inflammatory Activities of Flavanones from Glycyrrhiza glabra L. (licorice) Leaf Phytocomplexes: Identification of Licoflavanone as a Modulator of NF-kB/MAPK Pathway

Inflammation represents an adaptive response generated by injuries or harmful stimuli. Natural remedies represent an interesting alternative to traditional therapies, involving several biochemical pathways. Besides, the valorization of agrochemical wastes nowadays seems to be a feasible way to reduce the health spending and improve the accessibility at bioactive natural compounds. In this context, the chemical composition of three Glycyrrhiza glabra L. (licorice) leaf extracts, obtained through maceration or ultrasound-assisted method (fresh and dried leaves) was investigated. A guided fractionation obtained three main components: pinocembrin, glabranin and licoflavanone. All the extracts showed similar antioxidant properties, evaluated by 2,2'-diphenyl-1-picrylhydrazyl (DPPH) or 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) Diammonium Salt (ABTS) assay, while, among the isolated compounds, licoflavanone exhibited the best antioxidant activity. The anti-inflammatory activity of the extracts and the purified compounds was investigated in lipopolysaccharide (LPS)-stimulated RAW 264.7 murine macrophages. Extract C and licoflavanone showed a good anti-inflammatory activity without affecting cell viability, as they decreased nitrite levels even when used at 12.5 μg/mL (p < 0.005) and 50 μM concentration (p < 0.001), respectively. Interestingly, licoflavanone markedly decreased pro-inflammatory cytokines and cyclooxygenase 2/inducible nitric oxide synthase (COX-2/iNOS) expression levels (p < 0.001). A modulation of nuclear factor kappa B/mitogen-activated protein kinases (NF-kB/MAPK) pathway underlay such behavior, highlighting the potential of this natural compound as a new scaffold in anti-inflammatory drug research

State of the water sector report 2015

The Australian Water Association and Deloitte are pleased to present the State of the Water Sector Report 2015. The Report is the only one of its kind, reporting on the trends and insights of water sector professionals about their own industry. The survey results reveal attitudes and behaviours relating to a range of topics affecting the industry. This year marks the fifth year that the survey has been run and, as such, a summary of trends across the five years has been included in this year’s report. Trends observed over the last five years operational efficiency first emerged as an issue affecting the water sector in 2013, due to growing concerns about the need to control costs and demonstrate value for money, both within the sector itself and for customers. This rose to become the primary issue and area of concern in 2014 as operational costs continued to rise and new capital investment costs were being passed on to customers. In 2015 operational efficiency remains the second biggest issue for the industry, with efficiencies still to be gained through asset management, process improvement and works management and systems improvement. Skills shortages, and talent attraction and retention were of significant concern when the survey commenced five years ago, with the issue of ageing workforces in particular seen by many as a looming threat for the industry. However, in more recent years these concerns have almost halved due to a reduction in demand for additional staff and the greater availability of skilled labour, given construction activity in the mining industry has eased. Unconventional gas came onto the industry’s radar in 2012. last year, 70% of respondents stated that they believed unconventional gas had a significant to moderate effect on the overall management of ground- or surface water. In 2015, 55% of respondents stated that produced water from unconventional gas activities can be treated to a suitable quality for irrigation and other purposes, nevertheless highlighting some concerns in relation to the oil and gas sector impact. Although climate change was identified by 86% of respondents last year as posing a significant or moderate risk to sustainable management of water, sustainability is rated as less important than in previous years, with it being ranked as one of the top issues for the sector in 2011. This may be due to broader changes in community sentiment regarding environmental issues, and more benign weather conditions. While the sector believed security of supply was being managed well, climate change, as well as population growth, is viewed as one of the greatest challenges over the next five years. from a price and regulatory perspective, satisfaction with the role of economic regulators continues to increase slowly, and an increasing proportion of respondents support regulators making deterministic decisions on prices, rather than just monitoring prices. However, a price monitoring role is still favoured by more than three times as many respondents as deterministic pricing. 2015 Key issues The price of water and water regulation Water sector professionals’ perceptions of customer beliefs Sources of water Digital technology Asset management and operational efficiency -- State based reports are also available at AWA\u27s websit

Effect of Ferric Sodium EDTA administration, in combination with vitamin C, folic acid, copper gluconate, zinc gluconate and selenomethionine, on cardiovascular risk evaluation: exploration of the HRV frequency domain

diseases. Using the Heart Rate Variability (HRV) analysis is possible to provide an evaluation of the safety and the effectiveness of intervention. Objective: To evaluate the efficacy and safety of Ferric Sodium EDTA in combination with vitamin C, folic acid, copper gluconate, zinc gluconate and selenomethionine (Ferachel forte®) 2 tabs/day for 24 days in elderly patients with secondary anaemia, by exploring the HRV frequency domain. Methods: In 45 elderly patients with secondary anaemia and/or low-moderate kidney failure, laboratory values after administration of Ferric Sodium EDTA, 2 tabs a day, in combination with vitamin C, folic acid, copper gluconate, zinc gluconate and selenomethionine (Ferachel forte®) for 24 days (N=16 patients) or ferrous gluconate 63 mg/day added to saline solution, administered using intravenous access during the hospitalization period of 15 ± 5 days (N=29 patients) were evaluated. Also, ECG signals and bioelectrical impedance (BIA) were measured. Results: Oral iron supplementation with Ferric Sodium EDTA, in combination with vitamin C, folic acid, copper gluconate, zinc gluconate and selenomethionine (Ferachel forte®) confirmed to be effective and safe about the cardiovascular risk in old patients. This study showed the real superiority of the oral administration about the cardiovascular risk in elderly patients in comparison with intravenous administration of ferrous gluconate. Conclusion: This study confirms that Ferric Sodium EDTA combination (Ferachel forte®) can be a valid alternative to ferrous gluconate intravenous therapy (gold standard) in the treatment of secondary anaemia in elderly patients. In fact, during the treatment, efficacy results have been maintained without statistically significant variations about cardiovascular risk, evaluated by exploring the HRV frequency domain