Ilelic Acids A and B, Two Unusual Triterpenes with a Seven-Membered Ring from <i>Ilex latifolia</i>

Two unusual triterpenes, ilelic acids A (<b>1</b>) and B (<b>2</b>), together with their biosynthetic related compounds ilelic acids C (<b>3</b>) and D (<b>4</b>) were isolated from the leaves of <i>Ilex latifolia</i>. Their structures with absolute configurations were elucidated by spectroscopic analysis and modified Mosher’s method. The plausible biogenetic pathway of <b>1</b> and <b>2</b> is proposed. These triterpenes exhibited a potent inhibitory effect on MCF-7 and MDA-MB-231 cells

Ilelic Acids A and B, Two Unusual Triterpenes with a Seven-Membered Ring from <i>Ilex latifolia</i>

Two unusual triterpenes, ilelic acids A (<b>1</b>) and B (<b>2</b>), together with their biosynthetic related compounds ilelic acids C (<b>3</b>) and D (<b>4</b>) were isolated from the leaves of <i>Ilex latifolia</i>. Their structures with absolute configurations were elucidated by spectroscopic analysis and modified Mosher’s method. The plausible biogenetic pathway of <b>1</b> and <b>2</b> is proposed. These triterpenes exhibited a potent inhibitory effect on MCF-7 and MDA-MB-231 cells