30 research outputs found

    Mainstreaming the Social Sciences in Conservation

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    Despite broad recognition of the value of social sciences and increasingly vocal calls for better engagement with the human element of conservation, the conservation social sciences remain misunderstood and underutilized in practice. The conservation social sciences can provide unique and important contributions to society's understanding of the relationships between humans and nature and to improving conservation practice and outcomes. There are 4 barriers—ideological, institutional, knowledge, and capacity—to meaningful integration of the social sciences into conservation. We provide practical guidance on overcoming these barriers to mainstream the social sciences in conservation science, practice, and policy. Broadly, we recommend fostering knowledge on the scope and contributions of the social sciences to conservation, including social scientists from the inception of interdisciplinary research projects, incorporating social science research and insights during all stages of conservation planning and implementation, building social science capacity at all scales in conservation organizations and agencies, and promoting engagement with the social sciences in and through global conservation policy-influencing organizations. Conservation social scientists, too, need to be willing to engage with natural science knowledge and to communicate insights and recommendations clearly. We urge the conservation community to move beyond superficial engagement with the conservation social sciences. A more inclusive and integrative conservation science—one that includes the natural and social sciences—will enable more ecologically effective and socially just conservation. Better collaboration among social scientists, natural scientists, practitioners, and policy makers will facilitate a renewed and more robust conservation. Mainstreaming the conservation social sciences will facilitate the uptake of the full range of insights and contributions from these fields into conservation policy and practice

    Conservation social science: understanding and integrating human dimensions to improve conservation

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    It has long been claimed that a better understanding of human or social dimensions of environmental issues will improve conservation. The social sciences are one important means through which researchers and practitioners can attain that better understanding. Yet, a lack of awareness of the scope and uncertainty about the purpose of the conservation social sciences impedes the conservation community's effective engagement with the human dimensions. This paper examines the scope and purpose of eighteen subfields of classic, interdisciplinary and applied conservation social sciences and articulates ten distinct contributions that the social sciences can make to understanding and improving conservation. In brief, the conservation social sciences can be valuable to conservation for descriptive, diagnostic, disruptive, reflexive, generative, innovative, or instrumental reasons. This review and supporting materials provides a succinct yet comprehensive reference for conservation scientists and practitioners. We contend that the social sciences can help facilitate conservation policies, actions and outcomes that are more legitimate, salient, robust and effective

    Integration of Gene Dosage and Gene Expression in Non-Small Cell Lung Cancer, Identification of HSP90 as Potential Target

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    BACKGROUND: Lung cancer causes approximately 1.2 million deaths per year worldwide, and non-small cell lung cancer (NSCLC) represents 85% of all lung cancers. Understanding the molecular events in non-small cell lung cancer (NSCLC) is essential to improve early diagnosis and treatment for this disease. METHODOLOGY AND PRINCIPAL FINDINGS: In an attempt to identify novel NSCLC related genes, we performed a genome-wide screening of chromosomal copy number changes affecting gene expression using microarray based comparative genomic hybridization and gene expression arrays on 32 radically resected tumor samples from stage I and II NSCLC patients. An integrative analysis tool was applied to determine whether chromosomal copy number affects gene expression. We identified a deletion on 14q32.2-33 as a common alteration in NSCLC (44%), which significantly influenced gene expression for HSP90, residing on 14q32. This deletion was correlated with better overall survival (P = 0.008), survival was also longer in patients whose tumors had low expression levels of HSP90. We extended the analysis to three independent validation sets of NSCLC patients, and confirmed low HSP90 expression to be related with longer overall survival (P = 0.003, P = 0.07 and P = 0.04). Furthermore, in vitro treatment with an HSP90 inhibitor had potent antiproliferative activity in NSCLC cell lines. CONCLUSIONS: We suggest that targeting HSP90 will have clinical impact for NSCLC patients

    Nonspecific Induction of  -lactamase in Enterobacter cloacae

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    Management problems in international enviroments

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    xxi, 457 p.; 23 cm

    Tradition as a Peacebuilding Tool

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    The concept of tradition, rather like that of secularism, has come to mean different things to different people in a variety of contexts. This Chapter explores an understanding of tradition as that group of rules or practices which sits alongside core governing texts of groups within civil society. It identifies tradition as that which facilitates the contextualisation of civil society groups over time. It then examines how tradition could be used as a tool for engendering peaceful civil society relations. To do this it first explains the rationale for identifying plural religious traditions as important for strong civil society building, including for the protection of fundamental rights and the socio-economic well-being of a nation. Tradition is then proposed as a means of countering the exclusion of plural religious voices from the public square arising both as a result of the secular narrative manifesting itself in extreme forms of Laïcité and as a result of forms of theocracy and confessionalism. The chapter does this by identifying the development of the concept of tradition, setting out dictionary definitions, definitions within the discipline of law and their interaction and links with definitions within the three Abrahamic faiths. The overarching thesis drawing these threads together is that the various methods of forming and using tradition by intermediate institutions of civil society could inform the creation of a platform as a dialogical basis to build consensus amongst individuals, institutions of civil society and governments. This envisages a plurality of religious voices not as a threat but rather as a richly diverse canvas upon which to paint the interactions of civic life and formulate the law that governs those interactions
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