7,723 research outputs found
Cooperatively extending the range of indoor localisation
Whilst access to location based information has been mostly possible in the outdoor arena through the use of GPS, the provision of accurate positioning estimations and broad coverage in the indoor environment has proven somewhat problematic to deliver. Considering more time is spent in the indoor environment, the requirement for a solution is obvious. The topography of an indoor location with its many walls, doors, pillars, ceilings and floors etc. muffling the signals to from mobile devices and their tracking devices, is one of the many barriers to implementation. Moreover the characteristically noisy behaviour of wireless devices such as Bluetooth headsets, cordless phones and microwaves can cause interference as they all operate in the same band as Wi-Fi devices. The limited range of tracking devices such as Wireless Access Points (AP), and the restrictions surrounding their positioning within a buildings' infrastructure further exacerbate this issue, these difficulties provide a fertile research area at present. The genesis for this research is the inability of an indoor location based system (LBS) to locate devices beyond the range of the fixed tracking devices. The hypothesis advocates a solution that extends the range of Indoor LBS using Mobile Devices at the extremities of Cells that have a priori knowledge of their location, and utilizing these devices to ascertain the location of devices beyond the range of the fixed tracking device. This results in a cooperative localisation technique where participating devices come together to aid in the determination of location of devices which otherwise would be out of scope
Compton Scattering of Fe K alpha Lines in Magnetic Cataclysmic Variables
Compton scattering of X-rays in the bulk flow of the accretion column in
magnetic cataclysmic variables (mCVs) can significantly shift photon energies.
We present Monte Carlo simulations based on a nonlinear algorithm demonstrating
the effects of Compton scattering on the H-like, He-like and neutral Fe K alpha
lines produced in the post-shock region of the accretion column. The peak line
emissivities of the photons in the post-shock flow are taken into consideration
and frequency shifts due to Doppler effects are also included. We find that
line profiles are most distorted by Compton scattering effects in strongly
magnetized mCVs with a low white dwarf mass and high mass accretion rate and
which are viewed at an oblique angle with respect to the accretion column. The
resulting line profiles are most sensitive to the inclination angle. We have
also explored the effects of modifying the accretion column width and using a
realistic emissivity profile. We find that these do not have a significant
overall effect on the resulting line profiles. A comparison of our simulated
line spectra with high resolution Chandra/HETGS observations of the mCV GK Per
indicates that a wing feature redward of the 6.4 keV line may result from
Compton recoil near the base of the accretion column.Comment: Accepted for publication in MNRAS, 10 pages with 8 figure
Solutions of the fully compressible semi-geostrophic system
The fully compressible semi-geostrophic system is widely used in the modelling of large-scale atmospheric flows. In this paper, we prove rigorously the existence of weak Lagrangian solutions of this system, formulated in the original physical coordinates. In addition, we provide an alternative proof of the earlier result on the existence of weak solutions of this system expressed in the so-called geostrophic, or dual, coordinates. The proofs are based on the optimal transport formulation of the problem and on recent general results concerning transport problems posed in the Wasserstein space of probability measures
Performing smart sexual selves: A sexual scripting analysis of youth talk about internet pornography
CAUL read and publish agreement 2023In this article, we explore young New Zealanders’ use of sexual scripts in talk about Internet pornography (IP) to perform ‘smart’ sexual selves. Using sexual scripting theory, as developed by feminist discursive psychologists, our analysis of interview data generated with 10 youth (aged 16–18 years) highlights two commonly constructed sexual identities across youth talk; (i) the proficient Internet pornography user, and (ii) the astute Internet pornography viewer. The way these young people talk about portrayals of sexuality and gender in IP – and their ability to discern its artifice – suggests they are savvy consumers who are capable of using IP as a cultural resource (e.g. for learning, entertainment) while at the same time acknowledging it as a flawed representation of sex and sexuality. We discuss the implications of our findings for strengths-based sexuality education that supports sexual agency, proposing a justice-orientated approach grounded in the notion of ethical sexual citizenship.fals
Use of the short-term inflammatory response in the mouse peritoneal cavity to assess the biological activity of leached vitreous fibers.
We used a special-purpose glass microfiber sample, Johns-Manville Code 100/475, to study the effects of various acid and alkali treatments on biological activity as assessed by inflammation in the mouse peritoneal cavity, the leaching of Si, and the phase contrast optical microscopy (PCOM) fiber number. We used mild and medium treatments with oxalic acid and Tris buffer and harsh treatment with concentrated HCl and NaOH. Mild oxalic acid and Tris treatment for 2 weeks had no effect on any of the end-points, but prolonging the mild oxalic acid treatment time to 2 months reduced the biological activity and the fiber number. Medium oxalic acid treatment reduced the biological activity and the fiber number and caused a loss of Si. Medium Tris alkali treatment reduced the PCOM-countable fibers and the biological activity but did not cause a substantial loss of Si. Harsh treatment with strong HCl did not affect the fiber number or cause leaching but the biological activity was reduced; strong NaOH reduced the fiber number and biological activity, and caused marked leaching of Si. The medium oxalic acid conditions (pH 1.4) were more acid than those found in lung cells but produced the same effects (reduction in fiber number and biological activity) as the more physiological mild treatment (pH 4.0), when prolonged. This study suggests that medium oxalic acid treatment can be used as a short-term assay to compare loss of Si, reduction in fiber number, and change in biological activity of vitreous fibers.(ABSTRACT TRUNCATED AT 250 WORDS
Turning points in a qualitatively different social space: young adults’ reflections of alternative provision
There is a wealth of evidence suggesting that after being marginalised and excluded from school young people who attend Alternative Provision settings report positive relationships and experiences of learning. There is however very little research which explores the longer term outcomes of attending this sort of provision. Retrospective life history interviews were undertaken with 18 young adults in their early to mid-20s who had attended Alternative Provision in England. Interviews focused on schooling, exclusion, attending Alternative Provision and the impact of this on what they had done since leaving school up to their present situation. Analysis showed that the experience of attending Alternative Provision frequently constituted a turning point in a young person’s life story. This was due to the qualitatively different kind of social space experienced there
Electronic capture of patient-reported and clinician-reported outcome measures in an elective orthopaedic setting: a retrospective cohort analysis
Objectives To determine whether an entirely electronic system can be used to capture both patient-reported outcomes (electronic Patient-Reported Outcome Measures, ePROMs) as well as clinician-validated diagnostic and complexity data in an elective surgical orthopaedic outpatient setting. To examine patients' experience of this system and factors impacting their experience.
Design Retrospective analysis of prospectively collected data.
Setting Single centre series. Outpatient clinics at an elective foot and ankle unit in the UK.
Participants All new adult patients attending elective orthopaedic outpatient clinics over a 32-month period.
Interventions All patients were invited to complete ePROMs prior to attending their outpatient appointment. At their appointment, those patients who had not completed ePROMs were offered the opportunity to complete it on a tablet device with technical support. Matched diagnostic and complexity data were captured by the treating consultant during the appointment.
Outcome measures Capture rates of patient-reported and clinician-reported data. All information and technology (IT) failures, language and disability barriers were captured. Patients were asked to rate their experience of using ePROMs. The scoring systems used included EQ-5D-5L, the Manchester-Oxford Foot Questionnaire (MOxFQ) and the Visual Analogue Scale (VAS) pain score.
Results Out of 2534 new patients, 2176 (85.9%) completed ePROMs, of whom 1090 (50.09%) completed ePROMs at home/work prior to their appointment. 31.5% used a mobile (smartphone/tablet) device. Clinician-reported data were captured on 2491 patients (98.3%). The mean patient experience score of using Patient-Reported Outcome Measures (PROMs) was 8.55±1.85 out of 10 and 666 patients (30.61%) left comments. Of patients leaving comments, 214 (32.13%) felt ePROMs did not adequately capture their symptoms and these patients had significantly lower patient experience scores (p<0.001).
Conclusions This study demonstrates the successful implementation of technology into a service improvement programme. Excellent capture rates of ePROMs and clinician-validated diagnostic data can be achieved within a National Health Service setting
The extent of and factors associated with self-reported overdose and self-reported receipt of naloxone among people who inject drugs (PWID) in England, Wales and Northern Ireland.
BACKGROUND: Overdose is a major cause of death among PWID, and for opioid overdoses naloxone administration can reduce harm. However, globally there is limited national level data on the extent of non-fatal overdose and naloxone uptake. The first national level data on the extent of self-reported overdose and self-reported receipt of naloxone among UK PWID, providing a baseline to monitor the impact of the recent policy change regarding naloxone availability, is presented. METHODS: Data on self-reported overdose and receipt of naloxone during the preceding year for 2013-2014 from a national survey of PWID was analysed. Participants who reported injecting during the preceding year were included. RESULTS: Participants (3850) were predominantly male (75%); mean age was 36 years. The most commonly injected drugs were: heroin (91%), crack (45%) and amphetamine (29%). 15% (591) reported overdosing during the preceding year. There were no differences in the proportion reporting overdose by age or gender, but overdose was more common among those who: injected multiple drugs; recently ceased addiction treatment; injected with used needles/syringes; ever had transactional sex; had used a sexual health clinic or emergency department and lived in Wales or Northern Ireland. Among those reporting an overdose during the preceding year, a third reported two to four overdoses and 7.5% five or more overdoses; half reported receiving naloxone. Those reporting naloxone receipt in the preceding year were more likely to: live in Wales or Northern Ireland; ever received used needles/syringes; ever been imprisoned; and less likely to have injected two drug types. CONCLUSION: These data provide a baseline for monitoring the impact of the 2015 UK policy change to improve take-home naloxone access. Interventions tackling overdose should promote naloxone awareness and access, and target those who; are poly-drug injectors, have ceased treatment, share needles/syringes and whose drug use links to sexual activity
Chemical Modifications of Lipids and Proteins by Nonthermal Food Processing Technologies
A range of nonthermal techniques have demonstrated process efficacy in ensuring product safety, extension of shelf life, and in general a retention of key quality attributes. However, various physical, chemical and biochemical effects of nonthermal techniques on macro and micro nutrients are evident, leading to both desirable and undesirable changes in food products. The objective of this review is to outline the effects of nonthermal techniques on food chemistry and the associated degradation mechanisms with the treatment of foods. Oxidation is one of the key mechanisms responsible for undesirable effects induced by nonthermal techniques. Degradation of key macromolecules largely depends on the processing conditions employed. Various extrinsic and intrinsic control parameters of high-pressure processing, pulsed electric field, ultrasound processing, and cold atmospheric plasma on chemistry of processed food are outlined. Proposed mechanisms and associated degradation of macromolecules, i.e., proteins, lipids, and bioactive molecules resulting in food quality changes are also discussed
Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting
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