2,577 research outputs found
Vibrotactile Signal Generation from Texture Images or Attributes using Generative Adversarial Network
Providing vibrotactile feedback that corresponds to the state of the virtual
texture surfaces allows users to sense haptic properties of them. However,
hand-tuning such vibrotactile stimuli for every state of the texture takes much
time. Therefore, we propose a new approach to create models that realize the
automatic vibrotactile generation from texture images or attributes. In this
paper, we make the first attempt to generate the vibrotactile stimuli
leveraging the power of deep generative adversarial training. Specifically, we
use conditional generative adversarial networks (GANs) to achieve generation of
vibration during moving a pen on the surface. The preliminary user study showed
that users could not discriminate generated signals and genuine ones and users
felt realism for generated signals. Thus our model could provide the
appropriate vibration according to the texture images or the attributes of
them. Our approach is applicable to any case where the users touch the various
surfaces in a predefined way.Comment: accepted for EuroHaptics 2018: Haptics: Science, Technology, and
Applications, pp.25-3
Baby Pigs Have a Sweet Tooth!
Early gains are the cheapest. And you can get faster early gains by feeding a good pig starter. In this article, the others tell how pig starters can be made more palatable and also what should go into a good pig starter
Characterization of one-dimensional quantum channels in InAs/AlSb
We report the magnetoresistance characteristics of one-dimensional electrons
confined in a single InAs quantum well sandwiched between AlSb barriers. As a
result of a novel nanofabrication scheme that utilizes a 3nm-shallow wet
chemical etching to define the electrostatic lateral confinement, the system is
found to possess three important properties: specular boundary scattering, a
strong lateral confinement potential, and a conducting channel width that is
approximately the lithography width. Ballistic transport phenomena, including
the quenching of the Hall resistance, the last Hall plateau, and a strong
negative bend resistance, are observed at 4K in cross junctions with sharp
corners. In a ring geometry, we have observed Aharonov-Bohm interference that
exhibits characteristics different from those of the GaAs counterpart due to
the ballistic nature of electron transport and the narrowness of the conducting
channel width.Comment: pdf-file, 8 figures, to be published in Phys. Rev.
The Search for Supersymmetry at the Tevatron Collider
We review the status of searches for Supersymmetry at the Tevatron Collider.
After discussing the theoretical aspects relevant to the production and decay
of supersymmetric particles at the Tevatron, we present the current results for
Runs Ia and Ib as of the summer of 1997. To appear in the book "Perspectives in
Supersymmetry", edited by G.L. Kane, World Scientific.Comment: 84 pages with 31 figures imbedded using psfig.tex. Uses sprocl.st
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus
Cancer cells often co-opt post-transcriptional regulatory mechanisms to achieve pathologic expression of gene networks that drive metastasis. Translational control is a major regulatory hub in oncogenesis; however, its effects on cancer progression remain poorly understood. Here, to address this, we used ribosome profiling to compare genome-wide translation efficiencies of poorly and highly metastatic breast cancer cells and patient-derived xenografts. We developed dedicated regression-based methods to analyse ribosome profiling and alternative polyadenylation data, and identified heterogeneous nuclear ribonucleoprotein C (HNRNPC) as a translational controller of a specific mRNA regulon. We found that HNRNPC is downregulated in highly metastatic cells, which causes HNRNPC-bound mRNAs to undergo 3′ untranslated region lengthening and, subsequently, translational repression. We showed that modulating HNRNPC expression impacts the metastatic capacity of breast cancer cells in xenograft mouse models. In addition, the reduced expression of HNRNPC and its regulon is associated with the worse prognosis in breast cancer patient cohorts
ADHD presenting as recurrent epistaxis: a case report
Epistaxis is an important otorhinolaryngological emergency, which usually has an apparent etiology, frequently local trauma in children. Here we present a case report wherein the epistaxis was recalcitrant, and proved to have a psychiatric disorder as an underlying basis. The child was diagnosed with Attention Deficit/Hyperactivity Disorder, hyperactive type, which led to trauma to nasal mucosa due to frequent and uncontrolled nose picking. Treatment with atomoxetine controlled the patient's symptoms and led to a remission of epistaxis
Cancer cells exploit an orphan RNA to drive metastatic progression.
Here we performed a systematic search to identify breast-cancer-specific small noncoding RNAs, which we have collectively termed orphan noncoding RNAs (oncRNAs). We subsequently discovered that one of these oncRNAs, which originates from the 3' end of TERC, acts as a regulator of gene expression and is a robust promoter of breast cancer metastasis. This oncRNA, which we have named T3p, exerts its prometastatic effects by acting as an inhibitor of RISC complex activity and increasing the expression of the prometastatic genes NUPR1 and PANX2. Furthermore, we have shown that oncRNAs are present in cancer-cell-derived extracellular vesicles, raising the possibility that these circulating oncRNAs may also have a role in non-cell autonomous disease pathogenesis. Additionally, these circulating oncRNAs present a novel avenue for cancer fingerprinting using liquid biopsies
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