9 research outputs found
Vulnerable, yet Resilient: The Impact of Covid-10 on Latino-Owned Businesses in South Omaha
The effects of COVID-19 have been felt broadly, across Omaha’s Latino community. Latino-owned businesses are a group of particular relevance due to the importance that local business, economic development, employment, and wealth creation have on the community as a whole. Using survey data collected between September 2021 and January 2022 among Latino business owners in South Omaha, the current study seeks to provide an exploratory and descriptive analysis of the impact of the pandemic on this group. The survey was applied to a non-random convenience sampling of 121 Latino business owners. Thus, there is no intention for this survey to be representative of the entire population of Latino business owners, but rather to present an overview of the impact of the pandemic on the growing Latino community in South Omaha. This report is divided into five sections. First, we present a demographic overview of the business owners and the characteristics of their businesses pre-pandemic to set the context for the effects and response to the pandemic. Second, we describe the owners’ perceptions of the impact that the pandemic has had on their business and their corresponding industry. Third, we compare the owners’ perceptions of COVID-19’s impact between the two “pandemic years”: 2020 and 2021. Fourth, we analyze the recovery prospects as presented by these business owners. In the last section, we present the owners’ perception of the support provided by government agencies and the community
Examination of Ableist Educational Systems and Structures that Limit Access to Engineering Education through Narratives
The purpose of this paper is to examine how higher education systems limit access to engineering education for disabled and neurodivergent engineering students. Throughout this paper we will discuss ableism in higher education systems. Particularly, U.S. institutions and education are designed for non-disabled and neurotypical people rather than with accessibility for all despite legal efforts to improve access to education. We also provide two narratives from the authors that describe their experiences with having a disability and being neurodivergent in engineering education. Finally, we suggest other paradigms and methodologies engineering education researchers can utilize when conducting research on disability and neurodivergence in engineering
Multi-ancestry genome-wide association meta-analysis of Parkinson?s disease
Although over 90 independent risk variants have been identified for Parkinson’s disease using genome-wide association studies, most studies have been performed in just one population at a time. Here we performed a large-scale multi-ancestry meta-analysis of Parkinson’s disease with 49,049 cases, 18,785 proxy cases and 2,458,063 controls including individuals of European, East Asian, Latin American and African ancestry. In a meta-analysis, we identified 78 independent genome-wide significant loci, including 12 potentially novel loci (MTF2, PIK3CA, ADD1, SYBU, IRS2, USP8, PIGL, FASN, MYLK2, USP25, EP300 and PPP6R2) and fine-mapped 6 putative causal variants at 6 known PD loci. By combining our results with publicly available eQTL data, we identified 25 putative risk genes in these novel loci whose expression is associated with PD risk. This work lays the groundwork for future efforts aimed at identifying PD loci in non-European populations
2018 American Society of Consultant Pharmacists Annual Meeting & Exhibition
Poster abstracts are evaluated based on the following criteria: significance of the problem to healthy aging or medication management; innovativeness of ideas, methods, and/or approach; methodological rigor of methods and approach; presentation of finding; implications identified for future research, practice, and/or policy; and clarity of writing. Submissions are not evaluated through the peer-reviewed process used by The Consultant Pharmacist. Industry support is indicated, where applicable. Presenting author is in italics. The poster abstract presentation is supported by the ASCP Foundation
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Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease
Although over 90 independent risk variants have been identified for Parkinson’s disease using genome-wide association studies, most studies have been performed in just one population at a time. Here we performed a large-scale multi-ancestry meta-analysis of Parkinson’s disease with 49,049 cases, 18,785 proxy cases and 2,458,063 controls including individuals of European, East Asian, Latin American and African ancestry. In a meta-analysis, we identified 78 independent genome-wide significant loci, including 12 potentially novel loci (MTF2, PIK3CA, ADD1, SYBU, IRS2, USP8, PIGL, FASN, MYLK2, USP25, EP300 and PPP6R2) and fine-mapped 6 putative causal variants at 6 known PD loci. By combining our results with publicly available eQTL data, we identified 25 putative risk genes in these novel loci whose expression is associated with PD risk. This work lays the groundwork for future efforts aimed at identifying PD loci in non-European populations