1,731 research outputs found

    Cuarto Congreso Latinoamericano y Octavo Congreso Boliviano de Mastozoología

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    The Fourth Latin American Congress and the Eighth Bolivian Congress of Mastozoology was held in the city of La Paz between July 10 and 13, 2018 and was the scenario in which researchers from the entire region converged in order to dialogue in around the conservation and investigation of mammals. According to official figures, more than 200 people from across the region gathered at a congress that, as predicted, was highlighted by the excellent keynote speakers who were part of the 8 sessions addressed, for the diversity of topics that were presented in each one of the generated symposiums, and especially for its excellent organization by the hand of the committee in charge, of the volunteers, and of the logistical support.El Cuarto congreso Latinoamericano y el Octavo congreso Boliviano de Mastozoología se llevó a cabo en la ciudad de La Paz entre el 10 y el 13 de julio de 2018 y fue el escenario en el cual confluyeron investigadores de toda la región con el fin de dialogar en torno a la conservación e investigación de los mamíferos. De acuerdo con cifras oficiales, más de 200 personas provenientes de toda la región se reunieron en un congreso que, como se pronosticaba, se destacó por losexcelentes conferencistas magistrales que hicieron parte de las 8 sesiones abordadas, por la diversidad de temáticas que fueron presentadas en cada uno de los simposios generados, y sobre todo por su excelente organización de la mano del comité encargado, de los voluntarios, y del apoyo logístico

    Resolución nacional de especies amenazadas de Colombia

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    On September 15, 2017, with the issuance of Resolution 1912, the last list of wild species that are threatened at continental and marine levels in the national territory was established. This administrative act categorized different faunal and floristic groups into the Critical Hazard (CR), Endangered (EN) and Vulnerable (VU) categories based, as indicated in that document, on the criteria, sub-criteria and thresholds proposed by IUCN . However, the publication of this resolution raises numerous questions for multiple groups, especially mammals, which calls into question the usefulness of this act for the conservation of biodiversity.El 15 de septiembre del 2017, con la emisión de la Resolución 1912, se estableció el último listado de especies silvestres que se encuentran amenazadas a nivel continental y marino en el territorio nacional. Dicho acto administrativo categorizó a diferentes grupos faunísticos y florísticos en las categorías de Peligro crítico (CR), en Peligro (EN) y Vulnerable (VU) basado, según se indica en dicho documento, en los criterios, subcriterios y umbrales propuestos por la UICN. Sin embargo, la publicación de dicha resolución plantea numerosos cuestionamientos para múltiples grupos, en especial los mamíferos, lo que pone en tela de juicio la utilidad de este acto para la conservación de la biodiversidad

    Mammalogy Notes ahora se publica con el Open Journal System (OJS)

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    On our fifth birthday, and with the interest that Mammalogy Notes remains at the forefront of digital publishing systems, we have taken the steps to adopt version 3 of the Open Journal System (OJS) editorial system.En nuestro cumpleaños número cinco, y con el interés de que Mammalogy Notes se mantenga a la vanguardia de los sistemas de publicación digitales, hemos dado los pasos para adoptar la versión 3 del sistema editorial del Open Journal System (OJS)

    ¿Mastozoología por desconocer o mastozoología por conocer?

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    As a scientific discipline, mastozoology is our best approach to the methodical and systematic study of all aspects that are associated with mammals. Although, as a result of more than three centuries of history, enormous advances have been made in their knowledge, there are still innumerable questions, unresolved issues and problems to be solved. This means a huge opportunity for the exercise of the discipline itself, and, in addition, a call for attention to all generations of mastozoologists to fill these gaps.Como disciplina científica, la mastozoología es nuestra mejor aproximación al estudio metódico y sistemático de todos los aspectos que se asocian con los mamíferos. Aunque como resultado de más de tres siglos de historia se han hecho enormes avances en su conocimiento, aún quedan innumerables preguntas, temas sin resolver y problemas por solucionar. Esto significa una enorme oportunidad para el ejercicio mismo de la disciplina, y, además, un llamado de atención a todas las generaciones de mastozoólogos para llenar estos vacíos

    Mamíferos, historia natural y colecciones

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    In this issue of Mammalogy Notes, we feature three notes on range extension, seven notes on natural history, and four inventories of mammals. Contributions come from Colombia, Peru, Mexico, Brazil, and Venezuela. Additionally, we include three new contributions from the special series on biological collections of Colombian mammals. In this way, Mammalogy Notes keeps growing, improving, and contributing to the knowledge of neotropical mammals.En este número de Mammalogy Notes presentamos tres notas sobre extensiones de distribución, siete notas de historia natural y cuatro inventarios de mamíferos. Las contribuciones provienen de Colombia, Perú, México, Brasil y Venezuela. Adicionalmente, incluimos tres nuevos trabajos de la serie especial sobre colecciones de mamíferos de Colombia. De esta forma Mammalogy notes continúa creciendo, mejorando y aportando al conocimiento de los mamíferos neotropicales

    Redefining vascular repair: revealing cellular responses on PEUU—gelatin electrospun vascular grafts for endothelialization and immune responses on in vitro models

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    Tissue-engineered vascular grafts (TEVGs) poised for regenerative applications are central to effective vascular repair, with their efficacy being significantly influenced by scaffold architecture and the strategic distribution of bioactive molecules either embedded within the scaffold or elicited from responsive tissues. Despite substantial advancements over recent decades, a thorough understanding of the critical cellular dynamics for clinical success remains to be fully elucidated. Graft failure, often ascribed to thrombogenesis, intimal hyperplasia, or calcification, is predominantly linked to improperly modulated inflammatory reactions. The orchestrated behavior of repopulating cells is crucial for both initial endothelialization and the subsequent differentiation of vascular wall stem cells into functional phenotypes. This necessitates the TEVG to provide an optimal milieu wherein immune cells can promote early angiogenesis and cell recruitment, all while averting persistent inflammation. In this study, we present an innovative TEVG designed to enhance cellular responses by integrating a physicochemical gradient through a multilayered structure utilizing synthetic (poly (ester urethane urea), PEUU) and natural polymers (Gelatin B), thereby modulating inflammatory reactions. The luminal surface is functionalized with a four-arm polyethylene glycol (P4A) to mitigate thrombogenesis, while the incorporation of adhesive peptides (RGD/SV) fosters the adhesion and maturation of functional endothelial cells. The resultant multilayered TEVG, with a diameter of 3.0 cm and a length of 11 cm, exhibits differential porosity along its layers and mechanical properties commensurate with those of native porcine carotid arteries. Analyses indicate high biocompatibility and low thrombogenicity while enabling luminal endothelialization and functional phenotypic behavior, thus limiting inflammation in in-vitro models. The vascular wall demonstrated low immunogenicity with an initial acute inflammatory phase, transitioning towards a pro-regenerative M2 macrophage-predominant phase. These findings underscore the potential of the designed TEVG in inducing favorable immunomodulatory and pro-regenerative environments, thus holding promise for future clinical applications in vascular tissue engineering

    Development and validation of a model to predict ceiling of care in COVID-19 hospitalized patients

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    Background: Therapeutic ceiling of care is the maximum level of care deemed appropiate to offer to a patient based on their clinical profile and therefore their potential to derive benefit, within the context of the availability of resources. To our knowledge, there are no models to predict ceiling of care decisions in COVID-19 patients or other acute illnesses. We aimed to develop and validate a clinical prediction model to predict ceiling of care decisions using information readily available at the point of hospital admission. Methods: We studied a cohort of adult COVID-19 patients who were hospitalized in 5 centres of Catalonia between 2020 and 2021. All patients had microbiologically proven SARS-CoV-2 infection at the time of hospitalization. Their therapeutic ceiling of care was assessed at hospital admission. Comorbidities collected at hospital admission, age and sex were considered as potential factors for predicting ceiling of care. A logistic regression model was used to predict the ceiling of care. The final model was validated internally and externally using a cohort obtained from the Leeds Teaching Hospitals NHS Trust. The TRIPOD Checklist for Prediction Model Development and Validation from the EQUATOR Network has been followed to report the model. Results: A total of 5813 patients were included in the development cohort, of whom 31.5% were assigned a ceiling of care at the point of hospital admission. A model including age, COVID-19 wave, chronic kidney disease, dementia, dyslipidaemia, heart failure, metastasis, peripheral vascular disease, chronic obstructive pulmonary disease, and stroke or transient ischaemic attack had excellent discrimination and calibration. Subgroup analysis by sex, age group, and relevant comorbidities showed excellent figures for calibration and discrimination. External validation on the Leeds Teaching Hospitals cohort also showed good performance. Conclusions: Ceiling of care can be predicted with great accuracy from a patient's clinical information available at the point of hospital admission. Cohorts without information on ceiling of care could use our model to estimate the probability of ceiling of care. In future pandemics, during emergency situations or when dealing with frail patients, where time-sensitive decisions about the use of life-prolonging treatments are required, this model, combined with clinical expertise, could be valuable. However, future work is needed to evaluate the use of this prediction tool outside COVID-19

    Impacto bio-económico de cambios estratégicos en el manejo de búfalos de río Murrah

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    The aim of this paper was to evaluate the effects of a strategy of changes to manage the bio-economic efficiency of a Murrah Buffalo production system in the province of Camagüey, Cuba, located 210 north and 770 west, 217 meters above sea level. The climate is tropical humid (Aw) plain. The mean annual precipitations average 1 180 mm (71 % between May and October), and temperature is between 24 and 29° C. The local soil is carbonated brown, brown without carbonates, and reddish-brown fersiallitic. The system comprises 5 100 ha and has 536 workers/year. A strategy to introduce management changes in agro-technology, food, reproduction, replacement, health, salary policies, and training was implemented as part of an innovation package with a systemic and participatory approach. The evaluation lasted eight years, and it was critical to increase dairy production in more than 200 000 kg/year in 2012, in comparison to 2004, with improvements in natality and reduction of operational expenses of the system. It was concluded that the strategy had a determining effect on the system's indicators.El objetivo del trabajo fue evaluar los efectos de una estrategia de cambios en el manejo en la eficiencia bio-económica de un sistema cooperativo de producción de Búfalos Murrah de Camagüey en Cuba, localizado en los 210 Norte y los 770 Oeste a 217 msnm. El clima es tropical húmedo (Aw) de llanura. La media anual de las precipitaciones fue de 1 180 mm (71 % de mayo a octubre) y temperaturas entre 24 y 29° C. El suelo es pardo carbonatado, pardos sin carbonatos y fersialíticos pardo rojizos. El sistema ocupa un área de 5 100 ha y emplea 536 trabajadores/año. Una estrategia de cambios en el manejo agro-técnico, alimentario, reproductivo, de reemplazos, en salud, política de salarios y determinadas acciones de capacitación fue puesta en práctica como una especie de paquete innovador con enfoque sistémico y participativo. La evaluación se desarrolló durante ocho años y fue determinante en el incremento de la producción de leche en más de 200 000 kg/año en el 2012 respecto al 2004, con una mejora en la natalidad y reducción en los gastos operacionales del sistema. Se concluye que la estrategia tuvo un efecto determinante en el comportamiento favorable de los indicadores del sistema
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