Active cleaning technique for removing contamination from optical surfaces in space

An active cleaning technique for removing contaminants from optical surfaces in space was investigated with emphasis on the feasibility of using plasma exposure as a means of in-situ cleaning. The major work accomplished includes: (1) development of an in-situ reflectometer for use in conjunction with the contaminant film deposition/cleaning facility; (2) completion of Apollo Telescope Mount (ATM) filter treatment experiments to assess the effects of plasma exposure on the UV transmittance; (3) attempts to correlate the atomic oxygen flux with cleaning rate; (4) completion of in-situ butadien contamination/plasma cleaning/UV reflectance measurement experiments; (5) carbon cleaning experiments using various gases; (6) completion of silicone contamination/cleaning experiments; and (7) experiments conducted at low chamber pressures to determine cleaning rate distribution and contamination of surfaces adjacent to those being cleaned

An argument for incorporating sociological approaches into phenomenological analyses in engineering education research

Despite numerous research studies that have examined why women are underrepresented in engineering education programmes, the phenomenon is still not fully understood, and no effective general solutions have been found. In this context, analysing women’s experiences in engineering education can provide insights regarding the evolution of the students’ learning strategies and socialization processes as well as contextual factors that influence their choice to persist in or leave their courses. This paper explores the pertinence of enhancing phenomenological analyses conducted in engineering education research by incorporating sociological perspectives, drawing on sociological studies that explore the relationship between gender, STEM education and persistence in STEM courses. The aim is to contribute to building a conceptual framework that, on the one hand, captures lived experience in engineering education and, on the other hand, analyses the social settings around engineering itself, i.e., the objectively significant circumstances, that condition female students’ attitudes, behaviours, and expectations towards persisting or not in engineering courses. Conclusions suggest the conceptual framework around subjectively meaningful experiences, proposed by Alfred Schutz, who followed the phenomenological school of thought initiated by Edmund Husserl, might be useful in understanding not only (a) the representations of the subjective social world for women in engineering education (that induces feelings of identification, security, symbolic values, and ultimately social actions), but also (b) the intersubjective social system that structures daily life, legitimizes behavioural patterns, assigns roles, and defines group membership along education in engineering. Expanding engineering education researchers’ conceptions of phenomenology, to consider more of the structural issues that influence women’s experiences and choices, can help generate increasingly meaningful research findings

An argument for incorporating sociological approaches into phenomenological analyses in engineering education research

Despite numerous research studies that have examined why women are underrepresented in engineering education programmes, the phenomenon is still not fully understood, and no effective general solutions have been found. In this context, analysing women’s experiences in engineering education can provide insights regarding the evolution of the students’ learning strategies and socialization processes as well as contextual factors that influence their choice to persist in or leave their courses. This paper explores the pertinence of enhancing phenomenological analyses conducted in engineering education research by incorporating sociological perspectives, drawing on sociological studies that explore the relationship between gender, STEM education and persistence in STEM courses. The aim is to contribute to building a conceptual framework that, on the one hand, captures lived experience in engineering education and, on the other hand, analyses the social settings around engineering itself, i.e., the objectively significant circumstances, that condition female students’ attitudes, behaviours, and expectations towards persisting or not in engineering courses. Conclusions suggest the conceptual framework around subjectively meaningful experiences, proposed by Alfred Schutz, who followed the phenomenological school of thought initiated by Edmund Husserl, might be useful in understanding not only (a) the representations of the subjective social world for women in engineering education (that induces feelings of identification, security, symbolic values, and ultimately social actions), but also (b) the intersubjective social system that structures daily life, legitimizes behavioural patterns, assigns roles, and defines group membership along education in engineering. Expanding engineering education researchers’ conceptions of phenomenology, to consider more of the structural issues that influence women’s experiences and choices, can help generate increasingly meaningful research findings

Effect of Structural Parameters on Superconductivity in Fluorine-Free LnFeAsO1-y (Ln=La,Nd)

The crystal structure of LnFeAsO$_{1-y}$ (Ln = La, Nd) has been studied by the powder neutron diffraction technique. The superconducting phase diagram of NdFeAsO$_{1-y}$ is established as a function of oxygen content which is determined by Rietveld refinement. The small As-Fe bond length suggests that As and Fe atoms are connected covalently. FeAs$_4$-tetrahedrons transform toward a regular shape with increasing oxygen deficiency. Superconducting transition temperatures seem to attain maximum values for regular FeAs$_4$-tetrahedrons

Solar-Powered Automated Transportation: Feasibility and Visualization

A solar-powered automated transportation network (ATN) connecting the North and South campuses of San José State University with three passenger stations was designed, visualized, and analyzed in terms of its energy usage, carbon offset, and cost. The study’s methodology included the use of tools and software such as ArcGIS, SketchUp, Infraworks, Sketchup, Rhinoceros, and Autodesk 3DS Max. ATN vehicle energy usage was estimated using data from the university’s Park & Ride shuttle bus operation and by modeling with SUMOPy, the advanced simulation suite for the micro-traffic simulator SUMO. The energy study showed that an extensive solar photovoltaic (PV) canopy over the guideway and stations is sufficient for the network to run 24/7 in better-than-zero net-metered conditions—even if ridership were to increase 15% above that predicted from SJSU Park & Ride shuttle data. The resulting energy system has a PV-rated output of 6.2 MW, a battery system capacity of 9.8 MWh, and an estimated cost of $11.4 million USD. The solar ATN also produces 98% lower CO2 and PM2.5 emissions compared to the Park & Ride shuttle bus. A team of experts including urban planners, architects, and engineers designed and visualized the conceptual prototype, including a comprehensive video explaining the need for solar ATN and what a typical rider would experience while utilizing the system. This research demonstrates both benefits and challenges for solar-powered ATN, as well as its functionality within the urban built environment to serve diverse San José neighborhoods

Men’s Experiences with the Hockey Fans in Training Weight Loss and Healthy Lifestyle Program

Background: Increasing rates of chronic disease, especially in men, have led to an increased effort to implement lifestyle interventions focusing on healthy eating and physical activity. Men are underrepresented in lifestyle programs and some studies have observed that males prefer men-only programs that occur in the context of sports. This paper reviews men’s feedback regarding motivation for joining and overall experience in a 12-week lifestyle intervention in the context of junior level ice hockey teams. Methods: Men age 35-65 with a BMI ?28 were recruited from local ice hockey team fan bases in London and Sarnia Ontario, Canada and randomized to the 12-week lifestyle intervention or control group. Those who attended at least 6 of the 12 weekly sessions, including at least one session in the final six weeks (n=30) were asked to complete an online questionnaire upon finishing the active phase of the intervention. The questionnaire elicited reasons for joining the program, changes seen following their participation, and the usefulness of specific components of the program. Results: For the 27 men who completed the questionnaire, weight loss and a desire to increase physical activity were the two main reasons cited for joining the program. After the intervention, 100% of the men reported eating a healthier diet and 78% increased their activity level. Program satisfaction was high and 96% of men believed both the classroom and exercise components were useful. Conclusion: Our results support previous research showing increased levels of satisfaction in men when lifestyle interventions are run in...

Ten years later: An update on the status of collections of endemic Gulf of Mexico fishes put at risk by the 2010 Oil Spill

The 2010 Gulf of Mexico Deepwater Horizon was the largest oil spill in human history that occurred during a 12-week period in a region less than 100 km from the coast of Louisiana; however, after more than a decade of post-spill research, few definitives can be said to be known about the long-term impacts on the development and distribution of fishes in and around the region of the disaster. Here, we examine endemic Gulf of Mexico fish species that may have been most impacted by noting their past distributions in the region of the spill and examining data of known collecting events and observations over the last twenty years (ten years prior to the spill, ten years post-spill). Five years post-spill, it was reported that 48 of the Gulf’s endemic fish species had not been collected and, with expanded methods, we now report that 29 (of the 78 endemic species) have not been reported in collections since 2010 (five of these are only known from observations post-spill). Although the good news that some previously ‘missing’ species have been found may be cause to celebrate, the lack of information for many species remains a cause for concern given focused sampling efforts post-spill

Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab.

The Epidermal Growth Factor Receptor (EGFR) is selectively expressed on the surface of numerous tumours, such as non-small cell lung, ovarian, colorectal and head and neck carcinomas. EGFR has therefore become a target for cancer therapy. Cetuximab is a chimeric human/mouse monoclonal antibody (mAb) that binds to EGFR, where it both inhibits signaling and induces cell death by antibody-dependent cell mediated cytotoxicity (ADCC). Cetuximab has been approved for clinical use in patients with head and neck squamous cell carcinoma (HNSCC) and colorectal cancer. However, only 15-20% patients benefit from this drug, thus new strategies to improve cetuximab efficiency are required. We aimed to develop a reliable and easy preclinical mouse model to evaluate the efficacy of EGFR-targeted antibodies and examine the immune mechanisms involved in tumour regression. We selected an anti-mouse EGFR mAb, 7A7, which has been reported to be "mouse cetuximab" and to exhibit similar properties to its human counterpart. Unfortunately, we were unable to reproduce previous results obtained with the 7A7 mAb. In our hands, 7A7 failed to recognize mouse EGFR, both in native and reducing conditions. Moreover, in vivo administration of 7A7 in an EGFR-expressing HPV38 tumour model did not have any impact on tumour regression or animal survival. We conclude that 7A7 does not recognize mouse EGFR and therefore cannot be used as the mouse equivalent of cetuximab use in humans. As a number of groups have spent effort and resources with similar issues we feel that publication is a responsible approach