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    The epidemiology of acute encephalitis.

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    Encephalitis means inflammation of the brain matter. Despite being a rare condition, encephalitis is of public health importance worldwide because it has high morbidity and mortality. Yet, many details about its epidemiology have yet to be elucidated. This review attempts to summarise what is known about the epidemiology of the infective causes of encephalitis and is based on a literature search of the Medline archives. Infection is the most common cause identified, with viruses being the most important known aetiological agents. Incidence varies between studies but is generally between 3.5 and 7.4 per 100,000 patient-years. Encephalitis affects peoples of all ages; however, incidence is higher in the paediatric population. Although both sexes are affected, most studies have shown a slight predominance in males. Encephalitis occurs worldwide; some aetiologies have a global distribution (herpesviruses) while others are geographically restricted (arboviruses). Although definite epidemiological trends are evident, it is difficult to make generalisations as few population-based studies exist, most cases are not reported to health authorities, and many possible pathogens are implicated but in most cases a cause is never found. A better understanding of the epidemiology of this devastating disease will pave the way for better prevention and control strategies

    TCP in the Internet of Things: from ostracism to prominence

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    © 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.TCP has traditionally been neglected as a transport-layer protocol for the Internet of Things (IoT). However, recent trends and industry needs are favoring TCP presence in IoT environments. In this article, we describe the main IoT scenarios where TCP will be used. We then analyze the historically claimed issues of TCP in the IoT context. We argue that, in contrast to generally accepted wisdom, most of those possible issues fall in one of the following categories: i) are also found in well-accepted IoT end-to-end reliability mechanisms, ii) can be solved, or iii) are not actual issues. Considering the future prominent role of TCP in the IoT, we provide recommendations for lightweight TCP implementation and suitable operation in such scenarios, based on our IETF standardization work on the topic.Postprint (author's final draft
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