Revised Pacific-Antarctic plate motions and geophysics of the Menard Fracture Zone

A reconnaissance survey of multibeam bathymetry and magnetic anomaly data of the Menard Fracture Zone allows for significant refinement of plate motion history of the South Pacific over the last 44 million years. The right-stepping Menard Fracture Zone developed at the northern end of the Pacific-Antarctic Ridge within a propagating rift system that generated the Hudson microplate and formed the conjugate Henry and Hudson Troughs as a response to a major plate reorganization ∼45 million years ago. Two splays, originally about 30 to 35 km apart, narrowed gradually to a corridor of 5 to 10 km width, while lineation azimuths experienced an 8° counterclockwise reorientation owing to changes in spreading direction between chrons C13o and C6C (33 to 24 million years ago). We use the improved Pacific-Antarctic plate motions to analyze the development of the southwest end of the Pacific-Antarctic Ridge. Owing to a 45° counterclockwise reorientation between chrons C27 and C20 (61 to 44 million years ago) this section of the ridge became a long transform fault connected to the Macquarie Triple Junction. Following a clockwise change starting around chron C13o (33 million years ago), the transform fault opened. A counterclockwise change starting around chron C10y (28 millions years ago) again led to a long transform fault between chrons C6C and C5y (24 to 10 million years ago). A second period of clockwise reorientation starting around chron C5y (10 million years ago) put the transform fault into extension, forming an array of 15 en echelon transform faults and short linking spreading centers

Comment on "mantle flow drives the subsidence of oceanic plates"

Adam and Vidal (Reports, 2 April 2010, p. 83) reported sea-floor depth increasing as the square root of distance from the ridge along "mantle flow lines." However, their data actually support a depth-age relationship and "flattening" at older ages. We argue that no plausible physical mechanism supports their proposal that mantle flow drives subsidence

Inner body and outward appearance: The relationships among appearance orientation, eating disorder symptoms, and internal body awareness

Contains fulltext : 55374.pdf (publisher's version ) (Closed access)This study investigated the associations of appearance orientation and eating disorder symptoms with internal body awareness in an eating-disordered group of women and a general sample of women. In the eating-disordered group, appearance orientation was positively associated with internal body awareness. Eating disorders symptoms were negatively related to the awareness of bodily signals. No significant associations were found in the general sample of women. The results indicate that in eating-disordered individuals preoccupation with the body and eating-disordered behaviors are not only negatively associated with hunger, but with awareness of other bodily signals as well

Tailored anticoagulant treatment after a first venous thromboembolism: protocol of the Leiden Thrombosis Recurrence Risk Prevention (L-TRRiP) study - cohort-based randomised controlled trial

Introduction Patients with a first venous thromboembolism (VTE) are at risk of recurrence. Recurrent VTE (rVTE) can be prevented by extended anticoagulant therapy, but this comes at the cost of an increased risk of bleeding. It is still uncertain whether patients with an intermediate recurrence risk or with a high recurrence and high bleeding risk will benefit from extended anticoagulant treatment, and whether a strategy where anticoagulant duration is tailored on the predicted risks of rVTE and bleeding can improve outcomes. The aim of the Leiden Thrombosis Recurrence Risk Prevention (L-TRRiP) study is to evaluate the outcomes of tailored duration of long-term anticoagulant treatment based on individualised assessment of rVTE and major bleeding risks.Methods and analysis The L-TRRiP study is a multicentre, open-label, cohort-based, randomised controlled trial, including patients with a first VTE. We classify the risk of rVTE and major bleeding using the L-TRRiP and VTE-BLEED scores, respectively. After 3 months of anticoagulant therapy, patients with a low rVTE risk will discontinue anticoagulant treatment, patients with a high rVTE and low bleeding risk will continue anticoagulant treatment, whereas all other patients will be randomised to continue or discontinue anticoagulant treatment. All patients will be followed up for at least 2 years. Inclusion will continue until the randomised group consists of 608 patients; we estimate to include 1600 patients in total. The primary outcome is the combined incidence of rVTE and major bleeding in the randomised group after 2 years of follow-up. Secondary outcomes include the incidence of rVTE and major bleeding, functional outcomes, quality of life and cost-effectiveness in all patients.Ethics and dissemination The protocol was approved by the Medical Research Ethics Committee Leiden-Den Haag-Delft. Results are expected in 2028 and will be disseminated through peer-reviewed journals and during (inter)national conferences.Trial registration number NCT06087952