SAINT OF STEEL!!

In lieu of an abstract, below is the essay\u27s first paragraph. At the conclusion of each episode of the 50s TV western \u27The Lone Ranger,\u27 one of the characters would ask: \u27Who is that masked man?\u27 The viewers, of course, knew the identity of the hero, as he raced off, with the famous cry to his faithful steed, \u27HiYo Silver, Away!!!\u2

SAINT OF STEEL!!

In lieu of an abstract, below is the essay\u27s first paragraph. At the conclusion of each episode of the 50s TV western \u27The Lone Ranger,\u27 one of the characters would ask: \u27Who is that masked man?\u27 The viewers, of course, knew the identity of the hero, as he raced off, with the famous cry to his faithful steed, \u27HiYo Silver, Away!!!\u2

New insights into bacterial adaptation through in vivo and in silico experimental evolution

International audienceMicrobiology research has recently undergone major developments that have led to great progress towards obtaining an integrated view of microbial cell function. Microbial genetics, high-throughput technologies and systems biology have all provided an improved understanding of the structure and function of bacterial genomes and cellular networks. However, integrated evolutionary perspectives are needed to relate the dynamics of adaptive changes to the phenotypic and genotypic landscapes of living organisms. Here, we review evolution experiments, carried out both in vivo with microorganisms and in silico with artificial organisms, that have provided insights into bacterial adaptation and emphasize the potential of bacterial regulatory networks to evolve