Additional file 3: Table S1. of Glyceraldehyde-3-phosphate dehydrogenase is overexpressed in colorectal cancer onset

Clinicopathological and immunohistochemical data. Id, arbitrary number used to preserve the privacy of patients; a.u., arbitrary units; M, male; F, female; TNM staging system: T, primary tumour extent; N, regional lymph node involvement; M, absence or presence of distant metastasis. (PDF 547 kb

Additional file 2: Figure S1. of Glyceraldehyde-3-phosphate dehydrogenase is overexpressed in colorectal cancer onset

Mouse monoclonal anti-GAPDH antibody specificity. Anti-GAPDH antibody (sc-47724, Santa Cruz Biotechnology, Santa Cruz, CA, USA) specificity was proven by Western blot, staining a single band at 37 kDa. (PDF 249 kb

Additional file 1: File S1. of Glyceraldehyde-3-phosphate dehydrogenase is overexpressed in colorectal cancer onset

Supporting Materials and Methods. Detailed immunohistochemical staining, total protein extraction and Western blot analysis materials and methods. (PDF 312 kb

Additional file 1: of Lack of cytomegalovirus detection in human glioma

Methodological details and proceduries. (DOCX 40 kb

Clinical and pathological characteristics of CRC patients.

<p>(UK: unknown).</p

Significant associations between <i>TGFBR1 locus</i> haplotype and CRC stratified by age at diagnosis and sex.

<p>(CRC: colorectal cancer; C: controls; OR: odds ratio; CI: confidence interval).</p

Relative expression of the <i>TGFBR1</i> rs11466445 allele calculated from a standard curve.

<p>The <i>TGFBR1</i> allele ratios in patients with sporadic CRC (panel A) and controls (panel B). The ASE-negative area is represented by the colored rectangle between the cutoff values (0.78 and 1.27). The mean and standard deviation are shown for each sample.</p

Association between the <i>TGFBR1</i> H2 haplotype, <i>TGFBR1</i> ASE, and CRC.

<p>(CRC: colorectal cancer; C: controls; ASE: allele-specific expression; RR: relative risk; CI: confidence interval; PAR%: population attributable risk percent).</p

Association between <i>TGFBR1</i> H2 haplotype and <i>TGFBR1</i> ASE.

<p>(CRC: colorectal cancer; C: controls; RR: relative risk; CI: confidence interval).</p

Significant associations between individual <i>TGFBR1</i> polymorphisms and CRC stratified by age at diagnosis (<67 years).

<p>(MAF: minor allele frequency; OR: odds ratio; CI: confidence interval).</p