Marry & Burn by Rachel Rose

Review of Rachel Rose\u27s Marry & Burn

The Thing About Buffalo Berries

A little-known wild fruit, the buffalo berry thrives in Canadian forests—but its edibility regularly comes into question

Labor and the Labor Process in a Limited Entry Fishery

We examine aspects of labor in the harvesting sector of the surf clam/ocean quahog industry of the mid-Atlantic region of the United States in the context of limited entry. Vessel owners are both diversifying and cutting back on labor costs through crew consolidation in response to difficulties in the sea clam industry. A survey of crew-members on job satisfaction reveals more about the preferences and experiences of labor. We make predictions about the fate of labor under a new management regime based on individual transferable quotas. The analysis is intended to bring the interests of crew-members into the decision-making process and to improve the basis for predicting how future regulatory measures may affect crewing.fishery management, labor, crewing, Atlantic sea clams, limited entry, social impact, Environmental Economics and Policy, Labor and Human Capital, Resource /Energy Economics and Policy,

Development of New Synthetic Routes for Ebselen in Pursuit of the First Synthesis of Ebtellur

Ebselen, N-phenyl-1,2-benzoisoselenazol-3(2H)-one, an established anti-oxidant and cytoprotective agent, has been assessed for an array of pharmaceutical applications in treating a multitude of disorders and maladies. It has further been identified as an anti-microbial and anti-viral agent against multiple infectious agents and has even been FDA-approved for a variety of these applications. While ebselen has captured pharmaceutical interest, its tellurium analogue, ebtellur, has yet to be successfully obtained, and in only one case was an attempt to obtain ebtellur reported. We have developed multiple new synthetic routes specifically targeting the first synthesis of ebtellur and discuss the viability of each pathway herein

The TNFα-Transgenic Rat: Hippocampal Synaptic Integrity, Cognition, Function, and Post-Ischemic Cell Loss

The cytokine, tumor necrosis factor α (TNFα), is a key regulator of neuroinflammation linked to numerous neurodegenerative conditions and diseases. The present study used transgenic rats that overexpress a murine TNFα gene, under the control of its own promoter, to investigate the impact of chronically elevated TNFα on hippocampal synaptic function. Neuronal viability and cognitive recovery in TNFα Tg rats were also determined following an ischemic insult arising from reversible middle cerebral artery occlusion (MCAO). Basal CA3-CA1 synaptic strength, recorded in acute brain slices, was not significantly different between eight-week-old TNFα Tg rats and non-Tg rats. In contrast, slices from TNFα Tg rats showed significantly greater levels of long-term potentiation (LTP) in response to 100 Hz stimulation, suggesting that synaptic networks may be hyperexcitable in the context of elevated TNFα. Cognitive and motor deficits (assessed on the Morris Water Maze and Rotarod task, respectively) were present in TNFα Tg rats in the absence of significant differences in the loss of cortical and hippocampal neurons. TNF overexpression exacerbated MCAO-dependent deficits on the rotarod, but ameliorated cortical neuron loss in response to MCAO

Sexual Trauma History Does Not Moderate Treatment Outcome In Attachment-Based Family Therapy (ABFT) For Adolescents With Suicide Ideation

Despite the well-documented association between history of sexual trauma (HSA) and suicide ideation, HSA is largely overlooked in suicide treatment studies. Existing studies showed that patients with a HSA have a weaker treatment response. In this randomized clinical trial for suicide ideation, HSA did not moderate treatment outcome for Attachment-Based Family Therapy (ABFT). Adolescents responded better to ABFT than a control condition, regardless of HSA status. At baseline, adolescents with HSA were also more likely to report past suicide attempts than those without HSA, indicating that they are a particularly important subgroup to consider when developing and evaluating interventions that target suicide ideation. Findings suggest that ABFT is a robust intervention for suicide ideation regardless of HSA. (PsycINFO Database Record (c) 2013 APA, all rights reserved)(journal abstract

Predictors of new onsets of irritable bowel syndrome, chronic fatigue syndrome and fibromyalgia:the lifelines study

BACKGROUND: It has been claimed that functional somatic syndromes share a common etiology. This prospective population-based study assessed whether the same variables predict new onsets of irritable bowel syndrome (IBS), chronic fatigue syndrome (CFS) and fibromyalgia (FM). METHODS: The study included 152 180 adults in the Dutch Lifelines study who reported the presence/absence of relevant syndromes at baseline and follow-up. They were screened at baseline for physical and psychological disorders, socio-demographic, psycho-social and behavioral variables. At follow-up (mean 2.4 years) new onsets of each syndrome were identified by self-report. We performed separate analyses for the three syndromes including participants free of the relevant syndrome or its key symptom at baseline. LASSO logistic regressions were applied to identify which of the 102 baseline variables predicted new onsets of each syndrome. RESULTS: There were 1595 (1.2%), 296 (0.2%) and 692 (0.5%) new onsets of IBS, CFS, and FM, respectively. LASSO logistic regression selected 26, 7 and 19 predictors for IBS, CFS and FM, respectively. Four predictors were shared by all three syndromes, four predicted IBS and FM and two predicted IBS and CFS but 28 predictors were specific to a single syndrome. CFS was more distinct from IBS and FM, which predicted each other. CONCLUSIONS: Syndrome-specific predictors were more common than shared ones and these predictors might form a better starting point to unravel the heterogeneous etiologies of these syndromes than the current approach based on symptom patterns. The close relationship between IBS and FM is striking and requires further research

A finite volume shock-capturing solver of the fully coupled shallow water-sediment equations

This paper describes a numerical solver of well-balanced, 2D depth-averaged shallow water-sediment equations. The equations permit variable variable horizontal fluid density and are designed to model watersediment flow over a mobile bed. A Godunov-type, HLLC finite volume scheme is used to solve the fully coupled system of hyperbolic conservation laws which describe flow hydrodynamics, suspended sediment transport, bedload transport and bed morphological change. Dependent variables are specially selected to handle the presence of the variable density property in the mathematical formulation. The model is verified against analytical and semi-analytical solutions for bedload transport and suspended sediment transport, respectively. The well-balanced property of the equations is verified for a variable-density dam break flow over discontinuous bathymetry. Simulations of an idealised dam-break flow over an erodible bed are in excellent agreement with previously published results ([1]), validating the ability of the model to capture the complex interaction between rapidly varying flow and an erodible bed and validating the eigenstructure of the system of variable-density governing equations. Flow hydrodynamics and final bed topography of a laboratory-based 2D partial dam breach over a mobile bed are satisfactorily reproduced by the numerical model. Comparison of the final bed topographies, computed for two distinct sediment transport methods, highlights the sensitivity of shallow water-sediment models to the choice of closure relationships