Fixed drug eruption to cetirizine with positive lesional patch tests to the three piperazine derivatives

BACKGROUND: The H1-antihistamine cetirizine, a piperazine derivative widely used in daily practice, is rarely the cause of cutaneous drug reaction. Nevertheless, four cases of fixed drug eruption (FDE) as a result of this drug have been described recently. We present the case of a 45-year-old woman with a multilocalized FDE following oral intake of cetirizine for allergic rhinitis. METHODS: Patch testing with hydroxyzine 1% and 10% in petrolatum (Chemotechnique), and with powdered Zyrtec (cetirizine) and Xyzal (levocetirizine) pills, prepared at 20% in water and at 20% in petrolatum, was performed in both residual lesions and healthy skin. RESULTS: Positive results (++) to these drugs (24 h occlusion and readings at days 2 and 3) were obtained in residual lesions only. These results allowed us to confirm the drug responsible for this FDE and to study cross-reactions between antihistamines of the same chemical family. CONCLUSIONS: To the best of our knowledge, this is the first report of FDE to cetirizine with positive patch testing to hydroxyzine, cetirizine, and levocetirizine. This case highlights the importance of patch testing in the study of cutaneous drug reactions, namely FDE

Three-body description of direct nuclear reactions: Comparison with the continuum discretized coupled channels method

The continuum discretized coupled channels (CDCC) method is compared to the exact solution of the three-body Faddeev equations in momentum space. We present results for: i) elastic and breakup observables of d-12C at E_d=56 MeV, ii) elastic scattering of d-58Ni at E_d=80 MeV, and iii) elastic, breakup and transfer observables for 11Be+p at E_{11Be}/A=38.4 MeV. Our comparative studies show that, in the first two cases, the CDCC method is a good approximation to the full three-body Faddeev solution, but for the 11Be exotic nucleus, depending on the observable or the kinematic regime, it may miss out some of the dynamic three-body effects that appear through the explicit coupling to the transfer channel.Comment: 12 pages, 10 figures, accepted for publication in Physical Review

Multiple scattering effects in quasi free scattering from halo nuclei: a test to Distorted Wave Impulse Approximation

Full Faddeev-type calculations are performed for $^{11}$Be breakup on proton target at 38.4, 100, and 200 MeV/u incident energies. The convergence of the multiple scattering expansion is investigated. The results are compared with those of other frameworks like Distorted Wave Impulse Approximation that are based on an incomplete and truncated multiple scattering expansion.Comment: 7 pages, 16 figures, to be published in Phys. Rev.

First report of Scaphoideus titanus for Madeira Island

This is the first report of Scaphoideus titanus, the main vector of flavescence dor ee, for Madeira (Portugal) and also for Macaronesia. This new record currently represents its southernmost occurrence in Europe. This leafhopper is present in most of the primary wine production regions in the north of Madeira island. There were no symptoms of flavescence dor ee disease during the monitoring period from 2010 to 2017. The ability of S. titanus to survive in regions with a subtropical climate suggests that it may also live in the most meridional areas of the Mediterranean region where, until now, it has been absent.info:eu-repo/semantics/publishedVersio

Resposta de milho e soja à adubação fosfatada em latossolo amarelo muito argiloso de Paragominas - Pará.

FERTBIO 2006