13 research outputs found
Supplemental Figure 1 from Allele-specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–mutant Endometrial Cancer
Validation and gene expression analysis of ER mutant models</p
Supplemental Figure 4 from Allele-specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–mutant Endometrial Cancer
ER mutants do not affect proliferation, but down-regulate proteins associated with movement and impact migration</p
Supplemental Figure 5 from Allele-specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–mutant Endometrial Cancer
ER-Y537S and ER-D538G mutants drive proliferative gene expression signatures in vivo</p
Supplemental Table 1 from Allele-specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–mutant Endometrial Cancer
Differentially expressed genes from in vitro RNA-seq experiments</p
Supplemental Figure 2 from Allele-specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–mutant Endometrial Cancer
Comparison of mutant ER regulated genes and genes regulated by sustained estrogen signaling</p
Supplementary Materials and Methods from Allele-specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–mutant Endometrial Cancer
Supplementary Materials and Methods</p
Supplemental Figure 7 from Allele-specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–mutant Endometrial Cancer
In vivo exploration of novel therapeutic targets in ER active and mutant endometrial cancer</p
Supplemental Table 5 from Allele-specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–mutant Endometrial Cancer
Enrichment values for ER associating proteins in endometrial and breast cancer cell lines</p
Supplemental Table 3 from Allele-specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–mutant Endometrial Cancer
Differentially expressed genes from in vivo RNA-seq experiments</p
Supplemental Table 4 from Allele-specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–mutant Endometrial Cancer
Mutant ESR1 generation: gBlock used for template amplification</p