69 research outputs found

    Quelques Desmidiées (Algae, Zygophyceae) de Guyane française étudiées au M.E.B.

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    Les auteurs étudient à l'aide du M.E.B. vingt taxons appartenant à la famille des Desmidiacées et aux genres #Actinotaenium, #Cosmarium, #Desmidium, #Euastrum, #Micrasterias, #Phymatodocis, #Staurastrum, #Streptonema et #Xanthidium. Quarante documents photographiques, réunis en cinq planches, présentent des vues originales d'ensemble et de détails, en particulier de cinq espÚces ou variétés récemment décrites. Trois nouvelles variétés sont proposées pour les genres #Euastrum et #Micrasterias$. (Résumé d'auteur

    Nouveaux taxa de micro-algues dulçaquicoles pour le Burkina Faso (Afrique de l\'Ouest): I- Chlorophyta

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    L\'Ă©tude taxonimique des micro-algues Ă©chantillonnĂ©es dans le rĂ©servoir de BagrĂ© (Burkina Faso, Afrique de l\'Ouest), a permis d\'inventorier et de dĂ©crire 70 nouveaux taxa (Chlorophyta), qui se rĂ©partissent dans 11 familles, 29 genres. Parmi les familles, les Desmidiaceae sont les plus abondantes avec 44,3% puis viennent les Oocystaceae (15,7 %), les Scenedesmaceae en Ă©galitĂ© avec les Closteriaceae (11,4 %), les Dictyosphaeriaceae (4,3 %), les Chlorococcaceae qui sont en Ă©galitĂ© avec les Radiococcaceae et Volvocaceae (2,9 %) et enfin les Hydrodictyaceae, les Gloeocystaceae et les Phacotaceae avec chacune 1,4 %. Ces nouveaux taxa ont Ă©tĂ© observĂ©s et dĂ©crits grĂące Ă  un microscope photonique. Avec 70 nouvelles espĂšces inventoriĂ©es pour le Burkina Faso, le rĂ©servoir de BagrĂ© peut ĂȘtre considĂ©rĂ© comme un milieu favorable au dĂ©veloppement de certaines espĂšces de Chlorophyta. Keywords: Micro-algues, Chlorophyta, taxinomie, rĂ©servoir de BagrĂ©, Burkina Faso International Journal of Biological and Chemical Sciences Vol. 2 (4) 2008: pp. 508-52

    Étude des genres Actinotaenium (NĂ€g.) Teiling et Cosmarium Corda ex Ralfs,/i> (Desmidiaceae/Chlorophyta) dans les mares temporaires des rĂ©gions du Centre, de l’Est et du Nord du Burkina Faso

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    De nombreux travaux de systématique des micro-algues faits auparavant, ont concerné les genres Actinotaenium et Cosmarium dans certaines régions d’Afrique, particulièrement en Afrique centrale et de l’ouest. Au Burkina Faso, les travaux précédents sur la systématique des micro-algues ont généralement concerné l’ensemble des genres de chlorophyta prenant en compte les genres Cosmarium et Actinotaenium. Cependant, il n’y a pas encore eu d’études sur les micro-algues de mares temporaires. Une observation d’échantillons de phytoplancton récoltés dans des mares du centre, de l’est (zone soudanienne) et nord (zone sahélienne) du Burkina Faso en période hivernale de 2007, 2008 et 2009 a permis de rencontrer 39 espèces des genres Actinotaenium et Cosmarium dont 23 nouvelles pour le Burkina Faso. La description des taxons donnée permet de compléter la connaissance de la microflore dulçaquicole de l’Afrique de l’Ouest en général et du Burkina Faso en particulier. Les espèces nouvelles s’ajoutent à environ 67 taxons de Cosmarium et 641 de tous les genres confondus et qui avaient été déjà répertoriés au Burkina Faso avant ce travail. Parmi les espèces, les formes cosmopolites sont dominantes. Elles se rencontrent dans des étangs caractérisés par des eaux acides, alcalines et oligotrophes

    National Institutes of Health–Funded Cardiac Arrest Research: A 10‐Year Trend Analysis

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142427/1/jah32314.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142427/2/jah32314_am.pd

    Comparison of the complete genome sequencesof Bifidobacterium animalis subsp. lactis DSM 10140 and Bl-04

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    Bifidobacteria are important members of the human gut flora, especially in infants. Comparative genomic analysis of two Bifidobacterium animalis subsp. lactis strains revealed evolution by internal deletion of consecutive spacer-repeat units within a novel clustered regularly interspaced short palindromic repeat locus, which represented the largest differential content between the two genomes. Additionally, 47 single nucleotide polymorphisms were identified, consisting primarily of nonsynonymous mutations, indicating positive selection and/or recent divergence. A particular nonsynonymous mutation in a putative glucose transporter was linked to a negative phenotypic effect on the ability of the variant to catabolize glucose, consistent with a modification in the predicted protein transmembrane topology. Comparative genome sequence analysis of three Bifidobacterium species provided a core genome set of 1,117 orthologs complemented by a pan-genome of 2,445 genes. The genome sequences of the intestinal bacterium B. animalis subsp. lactis provide insights into rapid genome evolution and the genetic basis for adaptation to the human gut environment, notably with regard to catabolism of dietary carbohydrates, resistance to bile and acid, and interaction with the intestinal epithelium. The high degree of genome conservation observed between the two strains in terms of size, organization, and sequence is indicative of a genomically monomorphic subspecies and explains the inability to differentiate the strains by standard techniques such as pulsed-field gel electrophoresis

    Argonaute Autoantibodies as Biomarkers in Autoimmune Neurologic Diseases

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    OBJECTIVE: To identify and characterize autoantibodies (Abs) as novel biomarkers for an autoimmune context in patients with central and peripheral neurologic diseases. METHODS: Two distinct approaches (immunoprecipitation/mass spectrometry-based proteomics and protein microarrays) and patients' sera and CSF were used. The specificity of the identified target was confirmed by cell-based assay (CBA) in 856 control samples. RESULTS: Using the 2 methods as well as sera and CSF of patients with central and peripheral neurologic involvement, we identified Abs against the family of Argonaute proteins (mainly AGO1 and AGO2), which were already reported in systemic autoimmunity. AGO-Abs were mostly of immunoglobulin G 1 subclass and conformation dependent. Using CBA, AGO-Abs were detected in 21 patients with a high suspicion of autoimmune neurologic diseases (71.4% were women; median age 57 years) and only in 4/856 (0.5%) controls analyzed by CBA (1 diagnosed with small-cell lung cancer and the other 3 with Sjögren syndrome). Among the 21 neurologic patients identified, the main clinical presentations were sensory neuronopathy (8/21, 38.1%) and limbic encephalitis (6/21, 28.6%). Fourteen patients (66.7%) had autoimmune comorbidities and/or co-occurring Abs, whereas AGO-Abs were the only autoimmune biomarker for the remaining 7/21 (33.3%). Thirteen (61.9%) patients were treated with immunotherapy; 8/13 (61.5%) improved, and 3/13 (23.1%) remained stable, suggesting an efficacy of these treatments. CONCLUSIONS: AGO-Abs might be potential biomarkers of autoimmunity in patients with central and peripheral nonparaneoplastic neurologic diseases. In 7 patients, AGO-Abs were the only biomarkers; thus, their identification may be useful to suspect the autoimmune character of the neurologic disorder. CLASSIFICATION OF EVIDENCE: This study provides Class III evidence that AGO-Abs are more frequent in patients with autoimmune neurologic diseases than controls

    A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export

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    A systematic search for human ribosome biogenesis factors shows conservation of many aspects of eukaryotic ribosome synthesis with the well-studied process in yeast and identifies an export route of 60S subunits that is specific for higher eukaryotes
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