38 research outputs found

    Insight into topological and functional relationships of cytochrome c oxidase subunit I of Saccharomyces cerevisiae by means of intragenic complementation

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    AbstractIn yeast, revertants were selected from four respiratory deficient mutants carrying mutations in the cytochrome c oxidase subunit I gene. Intragenic second site mutations revealed amino acids which are functionally complementary to the original mutated position and may be in topological interaction with it. The results provide additional data in favour of the model proposed for the structure of the binuclear centre in proton-motive oxidases

    The BLLAST field experiment: Boundary-Layer late afternoon and sunset turbulence

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    Due to the major role of the sun in heating the earth's surface, the atmospheric planetary boundary layer over land is inherently marked by a diurnal cycle. The afternoon transition, the period of the day that connects the daytime dry convective boundary layer to the night-time stable boundary layer, still has a number of unanswered scientific questions. This phase of the diurnal cycle is challenging from both modelling and observational perspectives: it is transitory, most of the forcings are small or null and the turbulence regime changes from fully convective, close to homogeneous and isotropic, toward a more heterogeneous and intermittent state. These issues motivated the BLLAST (Boundary-Layer Late Afternoon and Sunset Turbulence) field campaign that was conducted from 14 June to 8 July 2011 in southern France, in an area of complex and heterogeneous terrain. A wide range of instrumented platforms including full-size aircraft, remotely piloted aircraft systems, remote-sensing instruments, radiosoundings, tethered balloons, surface flux stations and various meteorological towers were deployed over different surface types. The boundary layer, from the earth's surface to the free troposphere, was probed during the entire day, with a focus and intense observation periods that were conducted from midday until sunset. The BLLAST field campaign also provided an opportunity to test innovative measurement systems, such as new miniaturized sensors, and a new technique for frequent radiosoundings of the low troposphere. Twelve fair weather days displaying various meteorological conditions were extensively documented during the field experiment. The boundary-layer growth varied from one day to another depending on many contributions including stability, advection, subsidence, the state of the previous day's residual layer, as well as local, meso- or synoptic scale conditions. Ground-based measurements combined with tethered-balloon and airborne observations captured the turbulence decay from the surface throughout the whole boundary layer and documented the evolution of the turbulence characteristic length scales during the transition period. Closely integrated with the field experiment, numerical studies are now underway with a complete hierarchy of models to support the data interpretation and improve the model representations.publishedVersio

    Le traumatisme de la mort annoncée: transmission entre soignants et parents face à la maladie grave d’un enfant

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    Les auteurs proposent une réflexion sur les processus psychiques enclenchés chez les parents et les soignants suite à l’annonce d’une affection cérébrale grave d’un enfant, âgé de trois mois à seize ans (traumatisme crânien, tumeur cérébrale, affection neurologique). Ils relèvent que le traumatisme suscité par un tel événement réalise une effraction psychique et provoque des sentiments d’abattement, d’isolement et d’angoisse chez les parents ;il induit aussi un « traumatisme par contagion » chez les soignants. Le rôle de la relation soignants-parents et la fonction de l’annonce sont investigués à plusieurs niveaux. Les auteurs discutent des conditions nécessaires au partage du savoir du parent avec la connaissance du soignant, à l’étayage relationnel et à la relance des processus psychiques."The traumatism of announced death": transmissions between caregivers and parents confronted to a serious illness of the child. The authors propose to reflect on the psychic processes caused by the announcement of a child’s serious illness to the parents and professional caregivers. The children we refer to are between 3 months and 16 years old and suffer from severe cerebral affections (traumatic brain injury, brain tumor, neurological affection). The article also aims to show in which aspects the announcement has a value of traumatism for the parents (it causes feelings of anguish and insulation) and for the caregivers. The role of the relation caregivers-parents and the function of the announcement are investigated on several levels (cognitive, relational and intra-psychical levels).1er auteur :Isabelle Lambotte 2e auteur :Lotta De Coster 3e auteur :Françoise De Gheestinfo:eu-repo/semantics/publishe

    Quel accompagnement et quelle formation pour les soignants confrontés à l'annonce de diagnostics aux parents d'enfants gravement malades ?

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    Dans cet article, les auteurs abordent tout d’abord la souffrance des professionnels dans le cas d’annonce de diagnostics graves en pédiatrie. Pour mieux comprendre le vécu spécifique des soignants les auteurs se réfèrent aux notions de « traumatisme psychique » et de « ressources adaptatives ». L’importance d’un accompagnement institutionnel est ensuite soulignée. Celui-ci peut se décliner en différentes formes complémentaires :travail en équipe, supervision, groupe de parole, soutien psychologique et formation continue. En s’appuyant sur une recherche-action, les auteurs présentent un exemple de formation spécifique autour de l’annonce de diagnostics graves. Celle-ci invite les soignants à réfléchir sur les fonctions possibles de l’annonce auprès des parents et celle de l’équipe soignante aux différents moments-clés de l’annonce.info:eu-repo/semantics/publishe

    The parental experience and perception of giving birth under water for their first child and the related first parent-child interactions

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    The birth under water could be a way of bringing together the best of natural childbirth with modern medicine. This practice of childbirth excludes epidural analgesia but the hot bath itself attenuates labour pains. The authors present some results of a qualitative research carried out on 6 primigravid mothers and their partners on the impact of taking a hot water bath during labour, delivery and childbirth, on the birth experience and the early parent-child relationship. The methods that were used to study the perception of the birth experience and the early interaction with the baby on a conscious and unconscious level were an anamnesis, a semi-directive interview, a projective test and a test of differential semantics. Results concerning the mother showed that she described a richer experience of her body at the moment of childbirth, a feeling of being more active with better self control, a higher self esteem coming from the absence of medication, a better way of experiencing the active-passive duality of childbirth and an identification to the baby. In regards to the father, results showed that the waterbirth made him feel involved and important. In respect to the early mother-child relationship, the mothers described how the new-born baby participated actively in the interaction. In conclusion, it appears that the aquatic birth is associated with several positive aspects and that it contributes to creating good conditions for satisfying early parent-child relationship and interaction.info:eu-repo/semantics/publishe
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