Evaluación de factibilidad de una micro central hidroeléctrica doméstica en alta montaña

76 páginasEl presente trabajo plantea el diseño de una micro central hidroeléctrica en el Parque Nacional Natural Los Nevados, con el fin de abastecer un centro de investigación de la Universidad EIA. Para su concepción se realizará un estudio hidrológico que permita establecer el caudal de diseño de la central hidroeléctrica. Se estableció el punto que brinde una mayor eficiencia en relación a la caída y al caudal que presenta la red de drenaje del río Claro. Se plantea el diseño de las obras civiles necesarias para el correcto funcionamiento de la central, respetando siempre los parámetros técnicos y legales que garanticen la sostenibilidad del proyecto. El estudio culmina estableciendo los costos del proyecto incluidos sus costos de operación para una futura evaluación financiera que establezca la viabilidad de la central, basada en el presupuesto disponible del ente constructor.PregradoIngeniero(a) Civi

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population