Sindromul ADHD – Tulburare a hiperactivităţii cu deficit de atenţie. Rolul factorilor declanșatori în apariţia manifestărilor clinice

În lucrare sunt prezentate date referitoare la apariţia factorilor declanșatori și la aspectele clinico-terapeutice ale sindromului ADHD, care are o mare importanţă pentru diagnosticarea timpurie și iniţierea tratamentului corect. Tratamentul sindromului ADHD trebuie început cât mai timpuriu în spital și constă în administrarea preparatelor psihostimulante, antidepresive în combinare cu psihoterapie

Particularităţi clinico-evolutive şi terapeutice în epilepsia mioclonică severă

În lucrare sunt prezentate datele clinice, electroencefalografi ce şi strategiile terapeutice a doi copii cu epilepsie mioclonică severă. Au fost studiate manifestările clinice şi electroencefalografi ce la utilizarea diverselor medicamente antiepileptice. S-au evidenţiat manifestările clinice principale, care pot fi folosite ulterior de medici pentru diagnosticul diferenţiat şi indicarea tratamentului raţional oportun

Unele aspecte clinico-epidemiologice ale sindromului coronarian acut în morbiditatea și mortalitatea populației Republicii Moldova

Department of Emergency Medicine, Nicolae Testemitanu SUMPhBackground. Acute coronary syndrom with -ST segment elevation (SCA-STE) and without -ST segment elevation (SCA-NSTE) is a major health problem for the population of the Republic of Moldova. Of the patients with SCA 20-25% are patients with SCA-STE (IMA-ST) and 75-80% SCANSTE (API / IMA-NSTE). Objective of the study. Study of the clinical-epidemiological aspects of ACS. Material and Methods. Clinical and epidemiological data were obtained based on the analysis of statistical reports of MSM and PS during 2016-2020 (SR No. 30-helth,12-helth) and 140 application forms of the patients with ACS served by PEMS in 2020. Results. The study showed us an increase in the incidence of AMI of the population from 4,7 to 5,2 cases per 1000 inhabitants. In 2020, 1646 patients with AMI were hospitalized, including 436 died, hospital mortality being 26,49 %. The mortality of the population through AMI decreased from 56,3 cases in 2016 to 49,6 cases per 100 thousand population in 2020. The evaluation of 140 application forms for patients with ACS showed us a total average age of 65,0 ± 22,7 years, including women 69,7 ± 28,4 years and men 64,6 ± 20,8 years (P˂0.001). Conclusion. The share of ACS under 65 years of age was 32,2% women and 53.9% men and over 65 years of age 69,8% women and 46.1% men. Modifiable risk factors such as hypertension, diabetes and obesity were present respectively in 70,4%, 36,4% and 20,4% of the patients included in the study.Introducere. Sindromul coronarian acut cu supradenivelare de segment –ST (SCA-STE) și fără supradenivelare de segment - ST(SCA-NSTE) reprezintă o problemă majoră de sănătate pentru populația Republica Moldova. Dintre pacienții cu SCA 20-25% sunt pacienți cu SCA-STE(IMA-ST) și 75-80% SCA-NSTE(API/IMA-NSTE). Scopul lucrării. Studiul aspectelor clinico-epidemiologice ale SCA. Material și Metode. Datele clinice și epidemiologice au fost obținute în baza analizei rapoartelor statistice ale MSMPS în perioada anilor 2016 -2020 (RS Nr.30-săn,12-săn), cât și a 140 fișe de solicitare ale AMU cu SCA, deserviți în anul 2020. Rezultate. Studiul efectuat a demonstrat o creștere a incidenței prin IMA a populației de la 4,7 la 5,2 cazuri la 1000 locuitori. În anul 2020, la tratament staționar s-au aflat 1646 bolnavi cu IMA, inclusiv 436 au decedat, mortalitatea spitalicească constituind 26,49%. Mortalitatea populației prin IMA a scăzut de la 56,3 cazuri în anul 2016 la 49,6 cazuri, la 100 mii populație, în anul 2020. Evaluarea a 140 fișe de solicitare a pacienților cu Sindrom Coronarian Acut (SCA) ne-a demonstrat o vârstă medie totală de 65,0±22,7 ani, inclusiv la femei 69,7±28,4 ani și la bărbați 64,6±20,8 ani (P˂0.001). Concluzii. Ponderea SCA cu vârsta sub 65 de ani a constituit 32,2% la femei și 53,9% la bărbați și în vârsta de peste 65 ani 69,8% la femei și 46,1% la bărbați. Factorii de risc modificabili ca HTA, DZ și obezitatea au fost prezenți respectiv la 70,4%, 36,4% și 20,4% dintre pacienții studiului

A Low Reabsorbing Luminescent Solar Concentrator Employing π-Conjugated Polymers

A highly efficient thin-film luminescent solar concentrator (LSC) utilizing two π-conjugated polymers as antennae for small amounts of the valued perylene bisimide Lumogen F Red 305 is presented. The LSC exhibits high photoluminescence quantum yield, low reabsorption, and relatively low refractive indices for waveguide matching. A Monte Carlo simulation predicts the LSC to possess exceptionally high optical efficiencies on large scales.National Science Foundation (U.S.) (Graduate Research Fellowship Program (Grant No. 1122374))Eni S.p.A. (Firm) (Eni-MIT Solar Frontiers Alliance

Effect of Intra-molecular Disorder and Inter-molecular Electronic Interactions on the Electronic Structure of Poly-p-Phenylene Vinylene (PPV)

We investigate the role of intra-molecular conformational disorder and inter-molecular electronic interactions on the electronic structure of disorder clusters of poly-p-phenylene vinylene (PPV) oligomers. Classical molecular dynamics is used to determine probable molecular geometries, and first-principle density functional theory (DFT) calculations are used to determine electronic structure. Intra-molecular and inter-molecular effects are disentangled by contrasting results for densely packed oligomer clusters with those for ensembles of isolated oligomers with the same intra-molecular geometries. We find that electron trap states are induced primarily by intra-molecular configuration disorder, while the hole trap states are generated primarily from inter-molecular electronic interactions.Comment: 4 pages, 4 figures. Compile with pdflate

Clinical-epidemiological aspects of acute coronary syndrome in the morbidity and mortality in the Republic of Moldova

Department of Emergency Medicine, Nicolae Testemitanu State University of Medicine and Pharmacy, National Center of Prehospital Emergency Medical Care, Institute of Emergency Medicine Chisinau, the Republic of MoldovaBackground: Acute coronary syndrome (ACS) is associated with high costs of hospital care, frequent recurrences and high risks of sudden death and short-term mortality. Material and methods: The retrospective study was based on the evaluation of 140 patients who met the ACS criteria. Clinical and epidemiological data were obtained based on the analysis of statistical reports of the Ministry of Health during 2016-2020. Results: The mean age of the patients was 65.0 ± 27.7 years. Incidence of acute myocardial infarction (AMI) in the population increased from 4.7 to 5.2 cases per 1000 inhabitants. The study found the following occurrence of risk factors: history of cardiovascular disease – 42 (91.3 %) patients, hypertension in 35 (76.1%), obesity in 21 (45.6%), diabetes mellitus in 14 (30.4%) and smoking in 13 (28.3%). The share of risk factors in the male group was distributed as follows: history of cardiovascular disease – 82 (87.2%) patients, hypertension – 63 (67.1%) patients, smoking – 40 (42.5%) patients, diabetes mellitus – 27 (28.7%) patients and obesity was established in 24 (25.5%) of men. Conclusions: ACS affects men more frequently, compared to women, in a ratio of 2.04:1. People under the age of 65 years constitute 57.5%. The results of the study showed that compared to men, women with ACS were older and had significantly more comorbidities

NMR Studies of Some Zn and Cd Coordination Compounds Bearing 1,2-ciclohexanedionedioxime

A series of homobi- and polynuclear zinc and cadmium coordination compounds supported by 1,2-cyclohexanedionedioxime and bridging bidentate ligands: 4,4'-bipyridyl, 1,2-bis(4-pyridyl) ethane, 1,3-bis(4-pyridyl) propane and dipiridil sulfide were characterized by the experimental techniques of 1H and 13C NMR spectroscopy. Individual NMR data of compounds are consistent with their assignment as complexes

A multimode analysis of the gas-phase photoelectron spectra in oligoacenes

© 2004 American Institute of Physics. The electronic version of this article is the complete one and can be found at: http://dx.doi.org/10.1063/1.1687675DOI: 10.1063/1.1687675We present a multimode vibrational analysis of the gas-phase ultraviolet photoelectron spectra of the first ionization in anthracene, tetracene, and pentacene, using electron-vibration constants computed at the density functional theory level. The first ionization of each molecule exhibits a high-frequency vibronic structure; it is shown that this regularly spaced feature is actually the consequence of the collective action of several vibrational modes rather than the result of the interaction with a single mode. We interpret this feature in terms of the missing mode effect. We also discuss the vibronic coupling constants and relaxation energies obtained from the fit of the photoelectron spectra with the linear vibronic model

VALORIFICAREA INSTRUMENTELOR TIC ÎN DEZVOLTAREA COMPETENȚEI DE INVESTIGARE A PROCESELOR BIOLOGICE LA LICEENI

Complexitatea competenței de investigare biologică la liceeni evoluează în didactica  modernă odată cu instrumen­tele TIC. Utilizarea laboratorului digital care include atât componente software, cât și componente hardware în timpul lucrărilor practice și al experimentului biologic motivează elevii pentru cercetare. Activitățile practice cu utilizarea senzorilor laboratorului digital oferă posibilitatea de a îmbunătăți componenta aplicativă și investigațională, formând bazele instruirii prin cercetare. Planificarea eficientă a activităților de investigare de către cadrul didactic duce la realizarea finalităților așteptate în procesul de predare-învățare-evaluare.VALORIFICATION OF ICT TOOLS IN DEVELOPING THE HIGH SCHOOL STUDENTS’ INVESTIGATION COMPETENCE OF BIOLOGICAL PROCESSESThe complexity of biological investigation competence of high school students evolves in modern Didactics at the same time with ICT tools. The use of the digital lab, which includes the software programming system and the hardware computer system during practical work and biological experiment, keeps students interested in research. Thus, practical activities with digital lab sensors offer the opportunity to improve the applicative and investigative component forming the basis of research training. Teachers’ effective planning of the investigative activities leads to the achievement of the expected results in the teaching-learning-evaluation process.</p