A systematic review of Vancouver B2 and B3 periprosthetic femoral fractures

Aims The aim of this study was to investigate the outcomes of Vancouver type B2 and B3 fractures by performing a systematic review of the methods of surgical treatment which have been reported. Materials and Methods A systematic search was performed in Ovid MEDLINE, Embase and the Cochrane Central Register of Controlled Trials. For inclusion, studies required a minimum of ten patients with a Vancouver type B2 and/or ten patients with a Vancouver type B3 fracture, a minimum mean follow-up of two years and outcomes which were matched to the type of fracture. Studies were also required to report the rate of re-operation as an outcome measure. The protocol was registered in the PROSPERO database. Results A total of 22 studies were included based on the eligibility criteria, including 343 B2 fractures and 167 B3 fractures. The mean follow-up ranged from 32 months to 74 months. Of 343 Vancouver B2 fractures, the treatment in 298 (86.8%) involved revision arthroplasty and 45 (12.6%) were treated with internal fixation alone. A total of 37 patients (12.4%) treated with revision arthroplasty and six (13.3%) treated by internal fixation only underwent further re-operation. Of 167 Vancouver B3 fractures, the treatment in 160 (95.8%) involved revision arthroplasty and eight (4.8%) were treated with internal fixation without revision. A total of 23 patients (14.4%) treated with revision arthroplasty and two (28.6%) treated only with internal fixation required re-operation. Conclusion A significant proportion, particularly of B2 fractures, were treated without revision of the stem. These were associated with a higher rate of re-operation. The treatment of B3 fractures without revision of the stem resulted in a high rate of re-operation. This demonstrates the importance of careful evaluation and accurate characterisation of the fracture at the time of presentation to ensure the correct management. There is a need for improvement in the reporting of data in case series recording the outcome of the surgical treatment of periprosthetic fractures. We have suggested a minimum dataset to improve the quality of data in studies dealing with these fractures

Studies on human N-acetyltransferase

SIGLEAvailable from British Library Document Supply Centre- DSC:D171983 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Golang Embedded Run-Time

Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2017.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (page 51).Embedded systems are becoming increasingly complicated due to the emergence of SOCs (system-on-a-chip) with multiple cores, dizzying amounts of peripherals, and complicated virtual memory systems. Unfortunately, performant embedded systems for SOCs are still largely written in either bare-metal C or userspace C because high-level languages running in userspace can have too much latency. This thesis proposes a new system called G.E.R.T, the Golang Embedded Run-Time, for multi-core ARM processors. GERT is a modified version of the Go runtime for bare-metal operation on multi-core ARMv7a SOC's. It is used to evaluate the effectiveness of using a high-level, type-safe, and garbage collected language for embedded applications. G.E.R.T provides the multiprocessor support and basic memory abstractions of a typical embedded toolkit while also enabling the user to leverage the language features of Go in order to develop concurrent embedded programs that are easier to reason about than similar ones written in C.by Yanni Coroneos.M. Eng

Sphingolipid metabolites differentially regulate extracellular signal-regulated kinase (ERK) and stress-activated protein kinase (SPAK) cascades: Biochem.J.

NRC publication: Ye