51 research outputs found

    Number of probe sets showing a significantly altered abundance in muscle tissue.

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    <p>The number of altered probe sets between adjacent developmental stages in AP or HP offspring are indicated at horizontal arrows; the number of commonly altered probe sets between stages in AP and HP offspring are indicated at intersections; the number of probe sets showing a different abundance between HP and AP offspring at the same developmental stage are indicated at vertical arrows; small arrows at the numbers indicate a higher or lower probe set abundance, respectively.</p

    Affected pathways in muscle tissue between developmental stages and diets.

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    <p>Listed pathways between AP stages (white boxes) indicate shifts during development that are not found in HP offspring (black boxes) at the corresponding period. Pathways between HP stages indicate alterations that occur in HP offspring but not in AP offspring in the corresponding period. (Arrows between boxes show direction of comparison; small arrows indicate higher and lower transcript abundance, respectively. OXPHOS, oxidative phosphorylation; PLK, Polo-like kinase; mTOR, mammalian target of rapamycin; AMPK, AMP-activated protein kinase; IGF1, insulin-like growth factor 1; FA, Fatty acid; RAN, Ras-related nuclear protein).</p

    Functional annotation of muscle transcripts showing altered abundance between two developmental stages within either dietary group HP or AP (Ingenuity Pathway Analysis).

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    <p>Up and down indicate higher and lower abundance in later compared to earlier stages, respectively. P-value: significance of association between dataset and IP-pathways; Fischer's exact test.</p

    Experimental design.

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    <p>Fetuses and offspring of divergently fed sows were collected at 4 developmental stages. Fetuses were derived from 3 sows per dietary group. Offspring were full sibs of six litters per dietary group collected at 3 consecutive postnatal stages; HP = high protein, CP = crude protein, AP = adequate protein.</p

    Functional annotation of muscle transcripts showing altered abundance depending on the dietary group (HP vs. AP) within different developmental stages (Ingenuity Pathway Analysis).

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    <p>Up and down indicate higher and lower abundance in HP compared to AP, respectively. P-value: significance of association between dataset and IP-pathways; Fischer's exact test.</p

    Ensuring the Stability of Presidential Succession in the Modern Era: Report of the Fordham University School of Law Clinic on Presidential Succession

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    This Report outlines the recommendations of Fordham Law\u27s first Presidential Succession Clinic, whose nine students conducted their work during the 2010-2011 academic year under the guidance of Dean John D. Feerick and Adjunct Professors Dora Galacatos and Nicole A. Gordon. Their recommendations for resolving the gaps and weaknesses in the presidential succession system include: (1) statutes and executive branch actions to account for the absence of procedures for declaring the Vice President unable; (2) removing legislators from the line of succession and resolving ambiguities regarding the line of the succession; and (3) reforms for addressing the death or resignation of a presidential candidate

    Basic flavanol skeleton.

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    <p>Catechin possesses two benzene rings (called the A- and B-rings) and a dihydropyran heterocycle (the C-ring) with a hydroxyl group on carbon 3. The molecule possesses two stereogenic centers on carbons 2 and 3.</p

    Concentration-time curves of GC, EGC, EC and EGCG (initial concentrations, μmol/L: 27, 100, 35, and 100, respectively) in the Hohenheimer Gas Test incubation medium over 24 h.

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    <p>Values are means + SEM of 5 observations. Inset: concentration-time curves of the sum of catechins (GC, EGC, EC, EGCG) using either active or inactive incubation medium (IM).</p
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