The linear correlation between growth, production of lysine and dihydroxyacetone (DHA) and consumption of glucose indicates metabolic steady-state during the cultivation

<p><b>Copyright information:</b></p><p>Taken from "Metabolic responses to pyruvate kinase deletion in lysine producing "</p><p>http://www.microbialcellfactories.com/content/7/1/8</p><p>Microbial Cell Factories 2008;7():8-8.</p><p>Published online 13 Mar 2008</p><p>PMCID:PMC2322953.</p><p></p

The labelling patterns of the amino acids were determined from protein hydrolysates harvested at different cell dryx mass (CDM) concentrations during the cultivation

The amino acids shown here exemplarily stem form different parts of the metabolic network and comprise alanine (solid square), phenylalanine (open square), valine (closed circle), glycine (open circle), glutamate (closed triangle), threonine (open triangle) and serine (closed diamond). M(non labelled), M(single labelled) and M(double labelled) denote the relative fractions of the corresponding mass isotopomers.<p><b>Copyright information:</b></p><p>Taken from "Metabolic responses to pyruvate kinase deletion in lysine producing "</p><p>http://www.microbialcellfactories.com/content/7/1/8</p><p>Microbial Cell Factories 2008;7():8-8.</p><p>Published online 13 Mar 2008</p><p>PMCID:PMC2322953.</p><p></p

The actual flux values are represented by the thickness of the corresponding arrows

<p><b>Copyright information:</b></p><p>Taken from "Metabolic responses to pyruvate kinase deletion in lysine producing "</p><p>http://www.microbialcellfactories.com/content/7/1/8</p><p>Microbial Cell Factories 2008;7():8-8.</p><p>Published online 13 Mar 2008</p><p>PMCID:PMC2322953.</p><p></p