8 research outputs found
Did He Drown or was He Murdered?
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Ethics and Research on Bodies in the Jurisdiction of Coroners or Medical Examiners
- Author
- Publication venue
- 'Academic Forensic Pathology International'
- Publication date
- Field of study
Audit of necropsy reporting in East Anglia.
- Author
- Publication venue
- 'BMJ'
- Publication date
- Field of study
Theory and racial profiling: Shortcomings and future directions in research
- Author
- Ajzen I.
- American Civil Liberties Union
- Bernard T.J.
- Bittner E.
- Black D.
- Black D.
- Boydstun J.E.
- Boyle J.
- Brown M.K.
- Bureau of Transportation Statistics
- Calnon J.M.
- Campbell J.P.
- Cordner G.
- Cox S.M.
- Ekstrand L.E.
- Engel R.S.
- Federal Highway Administration
- Gallup News Service
- Harris D.A.
- Herszenhorn D.M.
- Jennifer M. Calnon
- Kennedy R.
- Lamberth J.
- Langan P.A.
- Lansdowne W.M.
- Manning P.K.
- Maxfield M.G.
- Quinney R.
- Robin Shepard Engel
- Rubinstein J.
- Skolnick J.H.
- Smith D.A.
- Smith W.R.
- Snipes J.B.
- Spitzer E.
- Stith S.M.
- Taylor J.
- Texas Department of Public Safety
- Thomas J. Bernard
- Turk A.T.
- Van Maanen J.
- Van Maanen J.
- Verniero P.
- Walker S.
- Washington State Patrol
- Wilson J.Q.
- Zingraff M. T.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Forensic Science, Wrongful Convictions, and American Prosecutor Discretion
- Author
- Arizona Office of the Auditor General
- Berger M.A.
- Boese A.
- Briody M.
- Bureau of Justice Statistics
- Bureau of Justice Statistics
- Bureau of Justice Statistics
- Center for Court Innovation
- Cheurprakobkit S.
- Cordner S.M.
- Craig L.A.
- Davis K.C.
- DeFrances C.J.
- DENNIS J. STEVENS
- Ellison K.W.
- Gordon S.G.
- Huff R.C.
- Kelly P.A.
- Lambert E.
- Lovrich N.P.
- Lumb R.
- Nelson C.L.
- Paternoster R.
- Saferstein R.
- Saverio F.R.
- Spohn C.
- Sternberg K.J.
- Stevens D.J.
- Stevens D.J.
- Stevens D.J.
- Stevens D.J.
- Toch H.
- US Courts
- Walker S.
- ‘Deadly speculation’
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Examining the influence of drivers' characteristics during traffic stops with police: Results from a national survey
- Author
- Ayres I.
- Ayres I.
- Ayres I.
- Bayley D.H.
- Beck A.J.
- Beck D.A.
- Becker G.S.
- Blubaugh J.A.
- Boyle J.
- Browning S.
- Chambliss W.J.
- Cole D.
- Cooper F.R.
- Cordner G.
- Cox S.M.
- Criminal Justice Training Commission
- Decker S.H.
- DuMouchel W.
- Eck J.
- Engel R.S.
- Engel R.S.
- Fridell L.
- General Accounting Office
- General Accounting Office
- Harris D.A.
- Harris D.A.
- Helmick D.O.
- Herszenhorn D.M.
- Institute on Race and Poverty
- Jennifer M. Calnon
- Kennedy R.
- LaFree G.
- Lamberth J.
- Landsdowne W.M.
- Langan P.A.
- Lange J.E.
- Lauritsen J.
- Lockwood D.
- Lohr S.L.
- Lynch J.P.
- MacDonald H.
- MacDonald H.
- Maguire K.
- Morgan J.G.
- National Conference of State Legislatures
- National Institute of Justice
- Novak K.J.
- Pennington D.L.
- Police Foundation
- Reilly R.
- Robin Shepard Engel
- Russell K.K.
- Scaglion R.
- Scalia J.
- Scheingold S.A.
- Scheingold S.A.
- Schmitt E.L.
- Skolnick J.H.
- Smith W.R.
- Spitzer E.
- Strom K.
- Substance Abuse and Mental Health Services Administration
- Taylor J.
- Taylor J.
- Tonry M.
- U.S. Department of Justice
- Verniero P.
- Walker S.
- Walker S.
- West C.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Interaction Between Circadian Rhythms, Energy Metabolism, and Cognitive Function
- Author
- Afzal A.S.
- Arnold S.E.
- Attuquayefio T.
- Barfield E.T.
- Bellisle F.
- Blancas-Velázquez A.
- Boitard C.
- Boitard C.
- Borbély A.A.
- Branecky K.L.
- Chaix A.
- Challet E.
- Chaudhury D.
- Chellappa S.L.
- Chen Y.
- Choi S.
- Cordner ZA
- Cserjési R.
- Dallman M.F.
- Davidson A.J.
- Davidson T.L.
- Davies J.A.
- de Goede P.
- de la Monte S.M.
- Del Olmo N.
- Del Olmo N.
- Del Rio D.
- Del Rio D.
- Devore E.E.
- Dickmeis T.
- Dinel A.L.
- Drover J.
- Eckel-Mahan K.L.
- Feillet C.A.
- Fick L.J.
- Fisk A.S.
- Francis H.
- Fuller P.M.
- Gerhart-Hines Z.
- Gerstner J.R.
- Gooley J.J.
- Greco J.A.
- Grillo C.A.
- Grillo C.A.
- Grillo C.A.
- Gritton H.J.
- Gritton H.J.
- Guo D.F.
- Hatori M.
- Hauber W.
- Herzog E.D.
- Herzog E.D.
- Hoffmann H.J.
- Huzard D.
- Inouye S.T.
- Jang H.
- Jilg A.
- Kaliyaperumal D.
- Kim J.J.
- Kim P.
- Kleitman N.
- Kohsaka A.
- Kovac J.
- Krieger D.T.
- Krishnan H.C.
- Kvarta M.D.
- Liang J.
- Liston C.
- Lizarbe B.
- Lyra E Silva N.M.
- Mackenberg E.J.
- Magistretti P.J.
- Mainardi M.
- Mariano Ruiz-Gayo
- McEwen B.S.
- Mendoza J.
- Mendoza J.
- Mendoza J.
- Mielke J.G.
- Milán-Tomás Á.
- Minakawa E.N.
- Mistlberger R.E.
- Moisan M.P.
- Molteni R.
- Morales L.
- Morin J.P.
- Morrison C.D.
- Naranjo V
- Nilsson L-G.
- Noble E.E.
- Nuria D. Olmo
- Oomura Y.
- Oosterman J.E.
- Osorio R.S.
- Partch C.L.
- Pendergast J.S.
- Preitner N.
- Prosser R.A.
- Rawashdeh O.
- Rawashdeh O.
- Reinke H.
- Resuehr D.
- Ruby N.F.
- Saderi N.
- Saper C.B.
- Saper C.B.
- Sato T.K.
- Schmidt C.
- Sen S.
- Sheward W.J.
- Shimizu K.
- Snider K.H.
- Sohn H.
- Soler J.E.
- Spencer J.P.E.
- Spencer S.J.
- Spinelli M.
- Spinelli M.
- Stephan F.K.
- Stephan F.K.
- Stephan F.K.
- Stephan F.K.
- Stevenson R.J.
- Stranahan A.M.
- Stucchi P.
- Takahashi J.S.
- Takahashi Y.
- Ukai-Tadenuma M.
- Valdez P.
- Valentinuzzi V.S.
- Valladolid-Acebes I.
- Valladolid-Acebes I.
- Van Doorn C.
- Vinuesa A.
- Wang L.M-C.
- Waterhouse J.
- Waterhouse J.
- Watts A.G.
- Welsh D.K.
- Winocur G.
- Wright K.P.
- Wright K.P.
- Wright K.P.
- Yau S-Y.
- Yi C.X.
- Yulyaningsih E.
- Publication venue
- 'Bentham Science Publishers Ltd.'
- Publication date
- Field of study
Pan-cancer analysis of whole genomes
- Author
- Aaltonen L.A.
- Abascal F.
- Abeshouse A.
- Aburatani H.
- Adams D.J.
- Agrawal N.
- Ahn K.S.
- Ahn S.M.
- Aikata H.
- Akbani R.
- Akdemir K.C.
- Al-Ahmadie H.
- Al-Sedairy S.T.
- Al-Shahrour F.
- Alawi M.
- Albert M.
- Aldape K.
- Alexandrov L.B.
- Ally A.
- Alsop K.
- Alvarez E.G.
- Amary F.
- Amin S.B.
- Aminou B.
- Ammerpohl O.
- Anderson M.J.
- Ang Y.
- Antonello D.
- Anur P.
- Aparicio S.
- Appelbaum E.L.
- Arai Y.
- Aretz A.
- Arihiro K.
- Ariizumi S.i.
- Armenia J.
- Arnau G.M.
- Arnould L.
- Asa S.
- Assenov Y.
- Atwal G.
- Aukema S.
- Auman J.T.
- Aure M.R.
- Awadalla P.
- Aymerich M.
- Bader G.D.
- Baez-Ortega A.
- Bailey M.H.
- Bailey P.
- Bailey P.J.
- Balasundaram M.
- Balu S.
- Bandopadhayay P.
- Banks R.E.
- Barbi S.
- Barbour A.P.
- Barenboim J.
- Barnholtz-Sloan J.
- Barr H.
- Barrera E.
- Bartlett J.
- Bartolome Javier
- Bassi C.
- Bathe O.F.
- Baumhoer D.
- Bavi P.
- Baylin S.B.
- Bazant W.
- Beardsmore D.
- Beck T.A.
- Behjati S.
- Behren A.
- Bell C.
- Beltran S.
- Benz C.
- Berchuck A.
- Bergmann A.K.
- Bergstrom E.N.
- Berman B.P.
- Berney D.M.
- Bernhart S.H.
- Beroukhim R.
- Berrios M.
- Bersani S.
- Bertl J.
- Betancourt M.
- Bhandari V.
- Bhosle S.G.
- Biankin A.V.
- Bieg M.
- Bigner D.
- Binder H.
- Birney E.
- Birrer M.
- Biswas N.K.
- Bjerkehagen B.
- Bodenheimer T.
- Boice L.
- Bonizzato G.
- Boot A.
- Bootwalla M.S.
- Borg A.
- Borkhardt A.
- Boroevich K.A.
- Borozan I.
- Borst C.
- Bosenberg M.
- Bosio M.
- Boultwood J.
- Bourque G.
- Boutros P.C.
- Bova G.S.
- Bowen D.T.
- Bowlby R.
- Bowtell D.D.L.
- Boyault S.
- Boyce R.
- Boyd J.
- Brazma A.
- Brennan P.
- Brewer D.S.
- Brinkman A.B.
- Bristow R.G.
- Broaddus R.R.
- Brock J.E.
- Brock M.
- Broeks A.
- Brooks A.N.
- Brooks D.
- Brors B.
- Brunak S.
- Bruxner T.J.C.
- Bruzos A.L.
- Buchanan A.
- Buchhalter I.
- Buchholz C.
- Bullman S.
- Burke H.
- Burkhardt B.
- Burns K.H.
- Busanovich J.
- Bustamante C.D.
- Butler A.P.
- Butte A.J.
- Byrne N.J.
- Børresen-Dale A.L.
- Caesar-Johnson S.J.
- Cafferkey A.
- Cahill D.
- Calabrese C.
- Caldas C.
- Calvo F.
- Camacho N.
- Campbell P.J.
- Campo E.
- Cantù C.
- Cao S.
- Carey T.E.
- Carlevaro-Fita J.
- Carlsen R.
- Cataldo I.
- Cazzola M.
- Cebon J.
- Cerfolio R.
- Chadwick D.E.
- Chakravarty D.
- Chalmers D.
- Chan C.W.Y.
- Chan K.
- Chan-Seng-Yue M.
- Chandan V.S.
- Chang D.K.
- Chanock S.J.
- Chantrill L.A.
- Chateigner A.
- Chatterjee N.
- Chayama K.
- Chen H.W.
- Chen J.
- Chen K.
- Chen Y.
- Chen Z.
- Cherniack A.D.
- Chien J.
- Chiew Y.E.
- Chin S.F.
- Cho J.
- Cho S.
- Choi J.K.
- Choi W.
- Chomienne C.
- Chong Z.
- Choo S.P.
- Chou A.
- Christ A.N.
- Christie E.L.
- Chuah E.
- Cibulskis C.
- Cibulskis K.
- Cingarlini S.
- Clapham P.
- Claviez A.
- Cleary S.
- Cloonan N.
- Cmero M.
- Collins C.C.
- Connor A.A.
- Cooke S.L.
- Cooper C.S.
- Cope L.
- Corbo V.
- Cordes M.G.
- Cordner S.M.
- Cortés-Ciriano I.
- Covington K.
- Cowin P.A.
- Craft B.
- Craft D.
- Creighton C.J.
- Cun Y.
- Curley E.
- Cutcutache I.
- Czajka K.
- Czerniak B.
- Dagg R.A.
- Danilova L.
- Davi M.V.
- Davidson N.R.
- Davies H.
- Davis I.J.
- Davis-Dusenbery B.N.
- Dawson K.J.
- De Bono J.S.
- De La Vega F.M.
- De Paoli-Iseppi R.
- deFazio A.
- Defreitas T.
- Dei Tos A.P.
- Delaneau O.
- Demchok J.A.
- Demeulemeester J.
- Demidov G.M.
- Demircioğlu D.
- Dennis N.M.
- Denroche R.E.
- Dentro S.
- Dentro S.C.
- Desai N.
- Deshpande V.
- Deshwar A.G.
- Desmedt C.
- Deu-Pons J.
- Dhalla N.
- Dhani N.C.
- Dhingra P.
- Dhir R.
- Diamanti K.
- DiBiase A.
- Ding L.
- Ding S.
- Dinh H.Q.
- Dirix L.
- Doddapaneni H.V.
- Donmez N.
- Dow M.T.
- Drapkin R.
- Drechsel O.
- Drews R.M.
- Dronov S.
- Dudderidge T.
- Dueso-Barroso A.
- Dunford A.J.
- Dunn M.
- Dursi L.J.
- Dursi L.J.
- Duthie F.R.
- Dutton-Regester K.
- Eagles J.
- Easton D.F.
- Edmonds S.
- Edwards P.A.
- Edwards S.E.
- Eeles R.A.
- Ehinger A.
- Eils J.
- Eils R.
- El-Naggar A.
- Eldridge M.
- Ellrott K.
- Erkek S.
- Escaramis G.
- Espiritu S.M.G.
- Estivill X.
- Etemadmoghadam D.
- Eyfjord J.E.
- Faltas B.M.
- Fan D.
- Fan Yu
- Faquin W.C.
- Farcas C.
- Fassan M.
- Fatima A.
- Favero F.
- Fayzullaev N.
- Felau I.
- Fereday S.
- Ferguson M.L.
- Ferretti V.
- Feuerbach L.
- Field M.A.
- Fink J.L.
- Finocchiaro G.
- Fisher C.
- Fittall M.W.
- Fittall M.W.
- Fitzgerald A.
- Fitzgerald R.C.
- Flanagan A.M.
- Fleshner N.E.
- Flicek P.
- Foekens J.A.
- Fong K.M.
- Fonseca N.A.
- Foster C.S.
- Fox N.S.
- Fraser M.
- Frazer S.
- Frenkel-Morgenstern M.
- Friedman W.
- Frigola J.
- Fronick C.C.
- Fujimoto A.
- Fujita M.
- Fukayama M.
- Fulton L.A.
- Fulton R.S.
- Furuta M.
- Futreal P.A.
- Futreal P.A.
- Füllgrabe A.
- Gabriel S.B.
- Gallinger S.
- Gambacorti-Passerini C.
- Gao J.
- Gao S.
- Garraway L.
- Garred Ø.
- Garrison E.
- Garsed D.W.
- Gehlenborg N.
- Gelpi J.L.
- George J.
- Gerhard D.S.
- Gerhauser C.
- Gershenwald J.E.
- Gerstein M.
- Gerstung M.
- Getz G.
- Ghori M.
- Ghossein R.
- Giama N.H.
- Gibbs R.A.
- Gill A.J.
- Gill P.
- Giri D.D.
- Glodzik D.
- Gnanapragasam V.J.
- Goebler M.E.
- Goldman M.
- Goldman M.J.
- Gomez C.
- Gonzalez S.
- Gonzalez-Perez A.
- Gonzalez-Perez A.
- Gordenin D.A.
- Gossage J.
- Gotoh K.
- Govindan R.
- Grabau D.
- Graham J.S.
- Grant R.C.
- Green A.R.
- Green E.
- Greger L.
- Grehan N.
- Grimaldi S.
- Grimmond S.M.
- Grossman R.L.
- Grundhoff A.
- Gundem G.
- Guo Q.
- Gupta M.
- Gupta S.
- Gut I.G.
- Gut M.
- Göke J.
- Ha G.
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- Haan D.
- Haas S.
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- Haber J.E.
- Habermann N.
- Hach F.
- Haider S.
- Hama N.
- Hamdy F.C.
- Hamilton A.
- Hamilton M.P.
- Han L.
- Hanna G.B.
- Hansmann M.
- Haradhvala N.J.
- Harismendy O.
- Harliwong I.
- Harmanci A.O.
- Harrington E.
- Hasegawa T.
- Haussler D.
- Hawkins S.
- Hayami S.
- Hayashi S.
- Hayes D.N.
- Hayes S.J.
- Hayward N.K.
- Hazell S.
- He Y.
- Heath A.P.
- Heath S.C.
- Hedley D.
- Hegde A.M.
- Heiman D.I.
- Heinold M.
- Heinold M.C.
- Heins Z.
- Heisler L.E.
- Hellstrom-Lindberg E.
- Helmy M.
- Heo S.G.
- Hepperla A.J.
- Heredia-Genestar José María
- Herrmann C.
- Hersey P.
- Hess J.M.
- Hilmarsdottir H.
- Hinton J.
- Hirano S.
- Hiraoka N.
- Hoadley K.A.
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- Howat W.
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- Hua X.
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- Hung J.A.
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- Jamieson N.B.
- Jan Komorowski None
- Jang G.H.
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- Kerssemakers J.N.A.
- Khoo D.
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- Kim J.K.
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- Kleinheinz K.
- Klimczak L.J.
- Knappskog S.
- Kneba M.
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- Knoppers B.M.
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- Korchina V.
- Korshunov A.
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- Kübler K.
- Küppers R.
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- Lehrach H.
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- Leongamornlert D.A.
- Leshchiner I.
- Letourneau L.
- Letunic I.
- Levine D.A.
- Lewis L.
- Ley T.
- Li C.
- Li C.H.
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Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale. Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter; identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation; analyses timings and patterns of tumour evolution; describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity; and evaluates a range of more-specialized features of cancer genomes