Implementación de nuevas tendencias de social media en las estrategias de marketing digital para emprendedores de la Dirección de Desarrollo Social y Económico del GAD Municipalidad de Ambato.

Technology and the use of the Internet revolutionized communication, because they presented new ways of explaining the world and cultural processes. In this context, the economy and trade have been altered, thanks to the strengthening of computer-mediated communities. Activities such as the use of social networks build the reputation of brands and promote emerging businesses, called ventures. In this sense, the present investigation focuses on the impact of social media trends on people considered within the so-called millennials, generation X and small business owners settled in the capital of the province of Tungurahua, the economy with the greatest contribution to GDP in the Center of Ecuador.La tecnología y el uso de internet revolucionaron la comunicación, porque presentaron nuevas formas de explicar el mundo y los procesos culturales. En ese contexto, la economía y el comercio se han alterado, gracias al fortalecimiento de las comunidades mediadas por computador. Actividades como el uso de las redes sociales construyen la reputación de las marcas y potencian negocios emergentes, llamados emprendimientos. En este sentido, la presente investigación se enfoca en el impacto de las tendencias social media en personas consideradas dentro de los denominados millennials, la generación X y los propietarios de pequeños negocios asentados en la capital de la provincia de Tungurahua, la economía con mayor aportación al PIB en el Centro del Ecuador

4D Biofabrication of fibrous artificial nerve graft for neuron regeneration

In this paper, we describe the application of the 4D biofabrication approach for the fabrication of artificial nerve graft. Bilayer scaffolds consisting of uniaxially aligned polycaprolactone-poly(glycerol sebacate) (PCL-PGS) and randomly aligned methacrylated hyaluronic acid (HA-MA) fibers were fabricated using electrospinning and further used for the culture of PC-12 neuron cells. Tubular structures form instantly after immersion of fibrous bilayer in an aqueous buffer and the diameter of obtained tubes can be controlled by changing bilayer parameters such as the thickness of each layer, overall bilayer thickness, and medium counterion concentration. Designed scaffolds showed a self-folded scroll-like structure with high stability after four weeks of real-time degradation. The significance of this research is in the fabrication of tuneable tubular nerve guide conduits that can simplify the current existing clinical treatment of neural injuries. © 2020 The Author(s). Published by IOP Publishing Ltd

Reversibly Photoswitchable High‐Aspect Ratio Surfaces

Herein, the fabrication of light‐sensitive high‐aspect ratio surfaces with switchable topography using melt‐electrowriting of shape‐memory polymers and deposition of light‐to‐heat converting black ink on it by dip coating is reported on. The lamellae exposed to low temperatures are hard and cannot be deformed by water droplets. The temperature reached upon illumination of surfaces is close to the melting point of the soft segment of the polyurethane that leads to softening of the polymer. Due to this, it is possible to locally deform and recover the light‐softened surface structures by water droplets deposited on lamellae. The deformed state can be fixed by cooling down resulting in the crystallization of the polymer. Thus, the reversibility of local deformation can be achieved. Finally, the application of the developed approach and materials for the fabrication of smart light‐controlled valves is demonstrated, which can be used for the controlled mixing of fluids in microfluidic devices