Analyzing the influence of oblique incidence on quantitative backscattering tissue polarimetry: a pilot ex vivo study

Significance Among the available polarimetric techniques, backscattering Mueller matrix (MM) polarimetry provides a promising non-contact and quantitative tool for in vivo tissue detection and clinical diagnosis. To eliminate the surface reflection from the sample cost-effectively, the non-collinear backscattering MM imaging setup always has an oblique incidence. Meanwhile, for practical organ cavities imaged using polarimetric gastrointestinal endoscopy, the uneven tissue surfaces can induce various relative oblique incidences inevitably, which can affect the polarimetry in a complicated manner and needs to be considered for detailed study. Aim The purpose of this study is to systematically analyze the influence of oblique incidence on backscattering tissue polarimetry. Approach We measured the MMs of experimental phantom and ex vivo tissues with different incident angles and adopted a Monte Carlo simulation program based on cylindrical scattering model for further verification and analysis. Meanwhile, the results were quantitatively evaluated using the Fourier transform, basic statistics, and frequency distribution histograms. Results Oblique incidence can induce different changes on non-periodic, two-periodic, and four-periodic MM elements, leading to false-positive and false-negative polarization information for tissue polarimetry. Moreover, a prominent oblique incidence can bring more dramatic signal variations, such as phase retardance and element transposition. Conclusions The findings presented in this study give some crucial criterions of appropriate incident angle selections for in vivo polarimetric endoscopy and other applications and can also be valuable references for studying how to minimize the influence further

SEPT: Towards Scalable and Efficient Visual Pre-Training

Recently, the self-supervised pre-training paradigm has shown great potential in leveraging large-scale unlabeled data to improve downstream task performance. However, increasing the scale of unlabeled pre-training data in real-world scenarios requires prohibitive computational costs and faces the challenge of uncurated samples. To address these issues, we build a task-specific self-supervised pre-training framework from a data selection perspective based on a simple hypothesis that pre-training on the unlabeled samples with similar distribution to the target task can bring substantial performance gains. Buttressed by the hypothesis, we propose the first yet novel framework for Scalable and Efficient visual Pre-Training (SEPT) by introducing a retrieval pipeline for data selection. SEPT first leverage a self-supervised pre-trained model to extract the features of the entire unlabeled dataset for retrieval pipeline initialization. Then, for a specific target task, SEPT retrievals the most similar samples from the unlabeled dataset based on feature similarity for each target instance for pre-training. Finally, SEPT pre-trains the target model with the selected unlabeled samples in a self-supervised manner for target data finetuning. By decoupling the scale of pre-training and available upstream data for a target task, SEPT achieves high scalability of the upstream dataset and high efficiency of pre-training, resulting in high model architecture flexibility. Results on various downstream tasks demonstrate that SEPT can achieve competitive or even better performance compared with ImageNet pre-training while reducing the size of training samples by one magnitude without resorting to any extra annotations.Comment: Accepted by AAAI 202

Parrot Captions Teach CLIP to Spot Text

Despite CLIP being the foundation model in numerous vision-language applications, the CLIP suffers from a severe text spotting bias. Such bias causes CLIP models to `Parrot' the visual text embedded within images while disregarding the authentic visual semantics. We uncover that in the most popular image-text dataset LAION-2B, the captions also densely parrot (spell) the text embedded in images. Our analysis shows that around 50% of images are embedded with visual text content, and around 30% of captions words are in these embedded visual content. Based on such observation, we thoroughly inspect the different released versions of CLIP models and verify that the visual text is the dominant factor in measuring the LAION-style image-text similarity for these models. To examine whether these parrot captions shape the text spotting bias, we train a series of CLIP models with LAION subsets curated by different parrot-caption-oriented criteria. We show that training with parrot captions easily shapes such bias but harms the expected visual-language representation learning in CLIP models. This suggests that it is urgent to revisit either the design of CLIP-like models or the existing image-text dataset curation pipeline built on CLIP score filtering.Comment: project page: https://linyq17.github.io/CLIP-Parrot-Bias/. Add more analysis and ablation studies. Update Figure 3 with a more precise metri

MiChao-HuaFen 1.0: A Specialized Pre-trained Corpus Dataset for Domain-specific Large Models

With the advancement of deep learning technologies, general-purpose large models such as GPT-4 have demonstrated exceptional capabilities across various domains. Nevertheless, there remains a demand for high-quality, domain-specific outputs in areas like healthcare, law, and finance. This paper first evaluates the existing large models for specialized domains and discusses their limitations. To cater to the specific needs of certain domains, we introduce the ``MiChao-HuaFen 1.0'' pre-trained corpus dataset, tailored for the news and governmental sectors. The dataset, sourced from publicly available internet data from 2022, underwent multiple rounds of cleansing and processing to ensure high quality and reliable origins, with provisions for consistent and stable updates. This dataset not only supports the pre-training of large models for Chinese vertical domains but also aids in propelling deep learning research and applications in related fields.Comment: 4 pages,2 figure

ShareGPT4V: Improving Large Multi-Modal Models with Better Captions

In the realm of large multi-modal models (LMMs), efficient modality alignment is crucial yet often constrained by the scarcity of high-quality image-text data. To address this bottleneck, we introduce the ShareGPT4V dataset, a pioneering large-scale resource featuring 1.2 million highly descriptive captions, which surpasses existing datasets in diversity and information content, covering world knowledge, object properties, spatial relationships, and aesthetic evaluations. Specifically, ShareGPT4V originates from a curated 100K high-quality captions collected from advanced GPT4-Vision and has been expanded to 1.2M with a superb caption model trained on this subset. ShareGPT4V first demonstrates its effectiveness for the Supervised Fine-Tuning (SFT) phase, by substituting an equivalent quantity of detailed captions in existing SFT datasets with a subset of our high-quality captions, significantly enhancing the LMMs like LLaVA-7B, LLaVA-1.5-13B, and Qwen-VL-Chat-7B on the MME and MMBench benchmarks, with respective gains of 222.8/22.0/22.3 and 2.7/1.3/1.5. We further incorporate ShareGPT4V data into both the pre-training and SFT phases, obtaining ShareGPT4V-7B, a superior LMM based on a simple architecture that has remarkable performance across a majority of the multi-modal benchmarks. This project is available at https://ShareGPT4V.github.io to serve as a pivotal resource for advancing the LMMs community.Comment: Project: https://ShareGPT4V.github.i

MLLM-DataEngine: An Iterative Refinement Approach for MLLM

Despite the great advance of Multimodal Large Language Models (MLLMs) in both instruction dataset building and benchmarking, the independence of training and evaluation makes current MLLMs hard to further improve their capability under the guidance of evaluation results with a relatively low human cost. In this paper, we propose MLLM-DataEngine, a novel closed-loop system that bridges data generation, model training, and evaluation. Within each loop iteration, the MLLM-DataEngine first analyze the weakness of the model based on the evaluation results, then generate a proper incremental dataset for the next training iteration and enhance the model capability iteratively. Compared with previous data collection methods which are separate from the benchmarking, the data generated by MLLM-DataEngine shows better targeting, quality, and correctness. For targeting, we propose an Adaptive Bad-case Sampling module, which adjusts the ratio of different types of data within each incremental dataset based on the benchmarking results. For quality, we resort to GPT-4 to generate high-quality data with each given data type. For correctness, prompt design is critical for the data generation results. Rather than previous hand-crafted prompt, we propose an Interactive Prompt Optimization strategy, which optimizes the prompt with the multi-round interaction between human and GPT, and improve the correctness of generated data greatly. Through extensive experiments, we find our MLLM-DataEngine could boost the MLLM capability in a targeted and automatic manner, with only a few human participation. We hope it could be a general solution for the following MLLMs building. The MLLM-DataEngine has been open-sourced and is now available at https://github.com/opendatalab/MLLM-DataEngine.Comment: Code and models are available at https://github.com/opendatalab/MLLM-DataEngin

ProtLLM: An Interleaved Protein-Language LLM with Protein-as-Word Pre-Training

We propose ProtLLM, a versatile cross-modal large language model (LLM) for both protein-centric and protein-language tasks. ProtLLM features a unique dynamic protein mounting mechanism, enabling it to handle complex inputs where the natural language text is interspersed with an arbitrary number of proteins. Besides, we propose the protein-as-word language modeling approach to train ProtLLM. By developing a specialized protein vocabulary, we equip the model with the capability to predict not just natural language but also proteins from a vast pool of candidates. Additionally, we construct a large-scale interleaved protein-text dataset, named InterPT, for pre-training. This dataset comprehensively encompasses both (1) structured data sources like protein annotations and (2) unstructured data sources like biological research papers, thereby endowing ProtLLM with crucial knowledge for understanding proteins. We evaluate ProtLLM on classic supervised protein-centric tasks and explore its novel protein-language applications. Experimental results demonstrate that ProtLLM not only achieves superior performance against protein-specialized baselines on protein-centric tasks but also induces zero-shot and in-context learning capabilities on protein-language tasks.Comment: https://protllm.github.io/project