1,044 research outputs found
Transport properties of dense deuterium-tritium plasmas
Consistent descriptions of the equation of states, and information about
transport coefficients of deuterium-tritium mixture are demonstrated through
quantum molecular dynamic (QMD) simulations (up to a density of 600 g/cm
and a temperature of eV). Diffusion coefficients and viscosity are
compared with one component plasma model in different regimes from the strong
coupled to the kinetic one. Electronic and radiative transport coefficients,
which are compared with models currently used in hydrodynamic simulations of
inertial confinement fusion, are evaluated up to 800 eV. The Lorentz number is
also discussed from the highly degenerate to the intermediate region.Comment: 4 pages, 3 figure
(E)-2-(4-Diethylamino-2-hydroxybenzylideneamino)benzonitrile
The molecule of the title compound, C18H19N3O, displays a trans configuration with respect to the C=N double bond. The dihedral angle between the planes of the two benzene rings is 2.62 (11)°. A strong intramolecular O—H⋯N hydrogen bond stabilizes the molecular conformation
3β-Acetoxy-8β,10β-dihydroxy-6β-methoxyeremophil-7(11)-en-8,12-olide
The title compound, C18H26O7, is an eremophilenolide which has been isolated from the plant Ligularia duciformis for the first time. The present study confirms the atomic connectivity assigned on the basis of 1H and 13C NMR spectroscopy. The molecule contains three fused rings, two six-membered rings in chair confomations and a five-membered ring in a flattened envelope conformation. Two hydroxy groups are involved in formation of intra- and intermolecular O—H⋯O hydrogen bonds. The latter ones link molecules into chains propagating in [010]
Construction of Novel Nanocomposites (Cu-MOF/GOD@HA) for Chemodynamic Therapy
The emerging chemodynamic therapy (CDT) has received an extensive attention in recent years. However, the efficiency of CDT is influenced due to the limitation of H2O2 in tumor. In this study, we designed and synthesized a novel core-shell nanostructure, Cu-metal organic framework (Cu-MOF)/glucose oxidase (GOD)@hyaluronic acid (HA) (Cu-MOF/GOD@HA) for the purpose of improving CDT efficacy by increasing H2O2 concentration and cancer cell targeting. In this design, Cu-MOF act as a CDT agent and GOD carrier. Cu(II) in Cu-MOF are reduced to Cu(I) by GSH to obtain Cu(I)-MOF while GSH is depleted. The depletion of GSH reinforces the concentration of H2O2 in tumor to improve the efficiency of CDT. The resultant Cu(I)-MOF catalyze H2O2 to generate hydroxyl radicals (·OH) for CDT. GOD can catalyze glucose (Glu) to supply H2O2 for CDT enhancement. HA act as a targeting molecule to improve the targeting ability of Cu-MOF/GOD@HA to the tumor cells. In addition, after loading with GOD and coating with HA, the proportion of Cu(I) in Cu-MOF/GOD@HA is increased compared with the proportion of Cu(I) in Cu-MOF. This phenomenon may shorten the reactive time from Cu-MOF to Cu(I)-MOF. The CDT enhancement as a result of GOD and HA effects in Cu-MOF/GOD@HA was evidenced by in vitro cell and in vivo animal studies
3a,11b-Dihydroxy-3a,11b-dihydro-1H-imidazo[4,5-f][1,10]phenanthroline-2(3H)-thione
The title compound, C13H10N4O2S, was prepared through a cyclization reaction of 1,10-phenanthroline-5,6-dione and thiourea. The dihedral angle between the pyridine rings is 8.22 (2)°. In the crystal, molecules are connected by N—H⋯O, O—H⋯N, N—H⋯S and O—H⋯S hydrogen bonds, forming a three-dimensional network
- …