Muon bibliography /

Brookhaven National Laboratory [operated by] Associated Universities, Inc. under contract with the U.S. Atomic Energy Commission. --c.p.Includes index prepared by L.M. Lederman."Physics -- TID-4500, 20th Ed."Includes bibliographical references (p. 1-17).Mode of access: Internet

Assessing the Environment for Support of Youth Physical Activity in Rural Communities.

OBJECTIVE: Assess environmental support of physical activity (PA) in rural areas and determine whether there is a correlation between the measured environment for PA and participant perceptions of the environment for PA. DESIGN: The PA environment was assessed using the Active Neighborhood Checklist (ANC) and the Physical Activity Resource Assessment (PARA). Youth behavior and perceptions related to PA and the local environment were assessed using 5 questions from previously validated tools. SETTING: Four rural low-income communities in South Dakota and Kansas. PARTICIPANTS: Sixth- through eighth-grade youth. VARIABLES MEASURED: Physical Activity Resource Assessment, ANC, behavior, and perception. ANALYSIS: The authors used ANOVA to determine whether there were differences in ANC, PARA, and Perception of the Environment scores among communities. Pearson correlations were used to assess associations between ANC and student perception of the environment and PARA and student perception of the environment. RESULTS: There were no differences in total ANC or total PARA among communities. Perception was weakly correlated with total ANC (multivariate coefficient, 0.016; P = .026; n = 308) but not total PARA. CONCLUSIONS AND IMPLICATIONS: Perception of PA in rural communities may not match objective measures. Future research should work toward refining and improving existing environmental audit tools and developing new, comprehensive, location-specific tools

Nasal bone evaluation in fetuses with Down syndrome during the second and third trimesters of pregnancy

Objective: this study examined the use of three-dimensional ultrasonography for evaluating the fetal nasal bone, as a sonographic marker of Down syndrome, during the second and early third trimesters of pregnancy. Methods: forty fetuses, including 20 with trisomy 21, were scanned once by three-dimensional ultrasonography. A midline sagittal view of the facial profile was used to analyze the volume data. Independent examiners reviewed blinded and randomly allocated volume data sets for the nasal bone. Interobserver reliability was evaluated for the sonographic presence or absence of the nasal bone. Logistic regression determined the contribution of this parameter to the presence of Down syndrome. Results: both examiners showed substantial agreement in scoring whether the nasal bone was visualized by three-dimensional ultrasonography (P < .001). They identified 40% to 45% of fetuses with abnormalities using the absence of the nasal bone as a sonographic marker. However, a substantial number of fetuses with abnormalities were also found to have a nasal bone present. The nasal bone was visualized in 80% to 90% of fetuses without abnormalities. Conclusions: three-dimensional ultrasonography can be used to evaluate the fetal nasal bone with substantial interobserver agreement during the second and early third trimesters of pregnancy. A nonvisualized nasal bone identified 40% to 45% of fetuses with Down syndrome in this stud

Dental Education Resources - historical

Walker, Paul O; Vukovich A.; Berendt, [], Scenes depicting attitudes of a clinical faculty member and a dental hygiene student and how they affect each other. Used for in-service program for dental hygiene faculty. (2:21) Orig. air date: MAY 26 72Walker, Paul O; Vukovich A.; Berendt, [], Scene depicting a dental hygiene student in a clinical experience; poor use of appointment time. Used for in-service program for Dental Hygiene faculty. (2:06) Orig. air date: MAY 26 72Walker, Paul O; Vukovich A.; Berendt, [], Enactment ofinteraction between adental hygiene clinical student and a new instructor; typical problems in this situation are demonstrated. (1:23) Orig. air date: MAY 26 72Robinson, Barbara, "Skills in Understanding the Other Person": This tape demonstrates two communication skills, paraphrasing and perceptions check to help the dental professional understand other people better. (8:01) Orig. air date: JUN 3 74O'Connor, Patricia; Silvian, Joseph, "Trigger Tapes - Workshop": Seven student-faculty lab or clinic situations are presented. The tapes are designed to trigger discussion of faculty members' behavior in the given situations. (15:02) Orig. air date: OCT 23 73Fisch, A. Linc, "Project 119 - Trigger Tapes on Learning/Teaching, Part I": Designed to generate discussion about clinic ethics. Several role playing situations are presented. (26:00) Orig. air date: FEB 9 72Fisch, A. Linc, "Project 119 - Trigger Tapes on Learning/Teaching, Part II": Presents staged situations that trigger""a dialogue on"" different aspects and problems in the teaching of Dental Students. (27:48) Orig. air date: FEB 9 72Walker, Paul O; Vukovich A.; Berendt, [], "Inconsistency": Deals with the problems students have when two different instructors review their work. (2:25) Orig. air date: MAR 1 72Comstock, Frank, "Dental Cubicle, Pt. 1- The Dental Unit": Introduces the University of Michigan School of Dentistry cubicle to the student. Shows the operation of the equipment. (28:07) Orig. air date: SEP 18 72Bagramian, Robert; Strawn, [], "Patient Education for Dental Health": Demonstrates a four step patient education sequence in use in private practices. (27:15) Orig. air date: OCT 8 75Bagramian, Robert, "Patient Education: Asset or Liability": Three successful practitioners discuss the role of patient education in Dentistry. The benefits, as well as the drawbacks, to the practitioner and the patient are covered. (19:32) Orig. air date: JAN 31 76Pape, Bud; Souers, [], "Your Role In Oral Hygiene": A patient education tape showing oral self exam, effects of dental plaque and way of dealing with plaque, use of disclosing solution, tooth brushing, and flossing. (19:21) Orig. air date: NOV 16 76Miller, Doris, "Trigger Tape - Patient Education": Five simulations depict interactions between a patient and Hygienist. They stimulate discussion concerning the inter- pertive and cognitive skill required of health professional (10:18) Orig. air date: JAN 17 75Comstock, Frank; Chasteen, Joseph, "Clean Techniques": A series of five clean technique demonstrations: (16:12) Orig. air date: SEP 10 75White, Stewart L., "Computers In The Pilot Program in Dentistry": Discusses the current and future uses of the computer, cost effectveness, and the potential for sharing. (25:45) Orig. air date: MAR 9 77Eddlemon, Charles; German, Marjorie, "Introduction to the Pilot Program in Dentistry": Discussion of progression of Pilot Program in Dentistry from its inception to present. (4:05) Orig. air date: MAY 11 76Eddlemon, Chuck; Mevis, Howard, "Achievements in the Pilot Program in Dentistry": A program describing methods in instructional design and development.Two courses that were developed at the University of Michigan School of Dentistry are presented . (19:25) Orig. air date: FEB 13 75Miller, Doris, "Trigger Tapes - Legal & Ethical Questions": Presents several vignettes that can be used to trigger"""" discussions in Dental health care professionals concerning legal and ethical questions in the Dental practice. (7:06) Orig. air date: MAR 6 75http://deepblue.lib.umich.edu/bitstream/2027.42/64983/2/102-3.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/3/102-5.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/4/102-6.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/5/134-3-4UnderstandSkills.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/6/136-3TriggerTapes.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/7/138-1TriggerTapes.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/8/177TriggerTapes.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/9/182-3Inconsistency.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/10/225-1DentalUnit.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/11/225-2PatientEducation.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/12/226-2PatienEducation.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/13/261-2OralHygiene.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/14/319-3PatientEducation.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/15/338-1CleanTechniques.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/16/339-2Computers.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/17/376-3Intro2PPD.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/18/411-2PPD.movhttp://deepblue.lib.umich.edu/bitstream/2027.42/64983/19/415-2TriggerTapes.mo

Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors

Novel Gram-positive (Gram+) antibacterial compounds consisting of a DNA polymerase IIIC (pol IIIC) inhibitor covalently connected to a topoisomerase/gyrase inhibitor are described. Specifically, 3-substituted 6-(3-ethyl-4-methylanilino)uracils (EMAUs) in which the 3-substituent is a fluoroquinolone moiety (FQ) connected by various linkers were synthesized. The resulting AU-FQ hybrid compounds were significantly more potent than the parent EMAU compounds as inhibitors of pol IIIC and were up to 64-fold more potent as antibacterials in vitro against Gram+ bacteria. The hybrids inhibited the FQ targets, topoisomerase IV and gyrase, with potencies similar to norfloxacin but 10-fold lower than newer agents, for example, ciprofloxacin and sparfloxacin. Representative hybrids protected mice from lethal Staphylococcus aureus infection after intravenous dosing, and one compound showed protective effect against several antibiotic-sensitive and -resistant Gram+ infections in mice. The AU-FQ hybrids are a promising new family of antibacterials for treatment of antibiotic-resistant Gram+ infections